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Prescriptions

Latest AI and machine learning research in prescriptions for healthcare professionals.

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Showing 1741-1760 of 9,065 articles

A real-world pharmacovigilance study on cardiovascular adverse events of tisagenlecleucel using machine learning approach.

Chimeric antigen receptor T-cell (CAR-T) therapies are a paradigm-shifting therapeutic in patients with hematological malignancies. However, some concerns remain that they may cause serious cardiovascular adverse events (AEs), for which data are scarce. In this study, gradient boosting machine algorithm-based model was fitted to identify safety signals of serious cardiovascular AEs reported for ti...

Jun 13 2024 38871843

IU-Net: A dual-path U-Net with rich information interaction for medical image segmentation.

Although the U-shape networks have achieved remarkable performances in many medical image segmentation tasks, they rarely model the sequential relationship of hierarchical layers. This weakness makes it difficult for the current layer to effectively utilize the historical information of the previous layer, leading to unsatisfactory segmentation results for lesions with blurred boundaries and irreg...

Jun 12 2024 38897032
DP-site: A dual deep learning-based method for protein-peptide interaction site prediction.

BACKGROUND: Protein-peptide interaction prediction is an important topic for several applications including various biological processes, understandin...

Jun 12 2024 38871095
Prediction of adverse drug reactions due to genetic predisposition using deep neural networks.

Drug development is a long and costly process, often limited by the toxicity and adverse drug reactions (ADRs) caused by drug candidates. Even on the ...

Jun 8 2024 38850150
Advances in artificial intelligence for drug delivery and development: A comprehensive review.

Artificial intelligence (AI) has emerged as a powerful tool to revolutionize the healthcare sector, including drug delivery and development. This revi...

Jun 7 2024 38878397
Two-Dimensional Deep Learning Frameworks for Drug-Induced Cardiotoxicity Detection.

The identification of drug-induced cardiotoxicity remains a pressing challenge with far-reaching clinical and economic ramifications, often leading to...

Jun 6 2024 38842187
Trust but Verify: Lessons Learned for the Application of AI to Case-Based Clinical Decision-Making From Postmarketing Drug Safety Assessment at the US Food and Drug Administration.

Adverse drug reactions are a common cause of morbidity in health care. The US Food and Drug Administration (FDA) evaluates individual case safety repo...

Jun 6 2024 38842929
ChatGPT: A Conceptual Review of Applications and Utility in the Field of Medicine.

Artificial Intelligence, specifically advanced language models such as ChatGPT, have the potential to revolutionize various aspects of healthcare, med...

Jun 5 2024 38836893
PPRTGI: A Personalized PageRank Graph Neural Network for TF-Target Gene Interaction Detection.

Transcription factors (TFs) regulation is required for the vast majority of biological processes in living organisms. Some diseases may be caused by i...

Jun 5 2024 38451769
Combined interaction of fungicides binary mixtures: experimental study and machine learning-driven QSAR modeling.

Fungicide mixtures are an effective strategy in delaying the development of fungicide resistance. In this research, a fixed ratio ray design method wa...

Jun 3 2024 38830957
An Explainable and Generalizable Recurrent Neural Network Approach for Differentiating Human Brain States on EEG Dataset.

Electroencephalogram (EEG) is one of the most widely used brain computer interface (BCI) approaches. Despite the success of existing EEG approaches in...

Jun 3 2024 36331650
Hybrid CNN-Transformer Network With Circular Feature Interaction for Acute Ischemic Stroke Lesion Segmentation on Non-Contrast CT Scans.

Lesion segmentation is a fundamental step for the diagnosis of acute ischemic stroke (AIS). Non-contrast CT (NCCT) is still a mainstream imaging modal...

Jun 3 2024 38319756
Artificial Intelligence in Drug Identification and Validation: A Scoping Review.

The end-to-end process in the discovery of drugs involves therapeutic candidate identification, validation of identified targets, identification of hi...

Jun 3 2024 38830370
Establishment of a risk prediction model for olfactory disorders in patients with transnasal pituitary tumors by machine learning.

To construct a prediction model of olfactory dysfunction after transnasal sellar pituitary tumor resection based on machine learning algorithms. A cro...

May 31 2024 38822064
Identification of drug responsive enhancers by predicting chromatin accessibility change from perturbed gene expression profiles.

Individual may response to drug treatment differently due to their genetic variants located in enhancers. These variants can alter transcription facto...

May 30 2024 38816426
Fillable Magnetic Microrobots for Drug Delivery to Cardiac Tissues In Vitro.

Many cardiac diseases, such as arrhythmia or cardiogenic shock, cause irregular beating patterns that must be regulated to prevent disease progression...

May 29 2024 38748937
Mechanism-based organization of neural networks to emulate systems biology and pharmacology models.

Deep learning neural networks are often described as black boxes, as it is difficult to trace model outputs back to model inputs due to a lack of clar...

May 27 2024 38802422
PfgPDI: Pocket feature-enabled graph neural network for protein-drug interaction prediction.

Biomolecular interaction recognition between ligands and proteins is an essential task, which largely enhances the safety and efficacy in drug discove...

May 27 2024 38812467
Deep learning predicts postoperative opioids refills in a multi-institutional cohort of surgical patients.

BACKGROUND: To combat the opioid epidemic, several strategies were implemented to limit the unnecessary prescription of opioids in the postoperative p...

May 25 2024 38796387
Evaluation of ChatGPT as a Tool for Answering Clinical Questions in Pharmacy Practice.

In the healthcare field, there has been a growing interest in using artificial intelligence (AI)-powered tools to assist healthcare professionals, in...

May 22 2024 38775367
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