Preventive Care

Generating evidence to support the role of AI in diabetic eye screening: considerations from the UK National Screening Committee.

Screening for diabetic retinopathy has been shown to reduce the risk of sight loss in people with diabetes, because of early detection and treatment of sight-threatening disease. There is long-standing interest in the possibility of automating parts of this process through artificial intelligence, commonly known as automated retinal imaging analysis software (ARIAS). A number of such products are ...

GCN-BBB: Deep Learning Blood-Brain Barrier (BBB) Permeability PharmacoAnalytics with Graph Convolutional Neural (GCN) Network.

The Blood-Brain Barrier (BBB) is a selective barrier between the Central Nervous System (CNS) and the peripheral system, regulating the distribution of molecules. BBB permeability has been crucial in CNS-targeting drug development, such as glioblastoma-related drug discovery. In addition, more CNS diseases still present significant challenges, for instance, neurological disorders like Alzheimer's ...

Integrative Multi-Omics and Routine Blood Analysis Using Deep Learning: Cost-Effective Early Prediction of Chronic Disease Risks.

Chronic noncommunicable diseases (NCDS) are often characterized by gradual onset and slow progression, but the difficulty in early prediction remains ...

Global disparities in artificial intelligence-based mammogram interpretation for breast cancer: A scientometric analysis of representation, trends, and equity.

BACKGROUND: Breast cancer (BC) is the most frequently diagnosed cancer and the leading cause of cancer death among women worldwide. Artificial intelli...

A Novel Natural Language Processing Tool Improves Colonoscopy Auditing of Adenoma and Serrated Polyp Detection Rates.

BACKGROUND AND STUDY AIMS: Determining adenoma detection rate (ADR) and serrated polyp detection rate (SDR) can be challenging as they usually involve...

An Early Thyroid Screening Model Based on Transformer and Secondary Transfer Learning for Chest and Thyroid CT Images.

IntroductionThyroid cancer is a common malignant tumor, and early diagnosis and timely treatment are crucial to improve patient prognosis. With the in...

Development and Multi-center validation of a machine learning Model for advanced colorectal neoplasms screening.

BACKGROUND: In colorectal cancer (CRC) screening programs, accurately identifying individuals at high risk for advanced colorectal neoplasia (ACN) is ...

In silico discovery of novel compounds for FAK activation using virtual screening, AI-based prediction, and molecular dynamics.

Focal Adhesion Kinase (FAK) is a non-receptor tyrosine kinase that plays a crucial role in cell proliferation, migration, and signal transduction. FAK...

Systems biology of Haemonchus contortus - Advancing biotechnology for parasitic nematode control.

Parasitic nematodes represent a substantial global burden, impacting animal health, agriculture and economies worldwide. Of these worms, Haemonchus co...

Optimizing deep learning models for glaucoma screening with vision transformers for resource efficiency and the pie augmentation method.

Glaucoma is the leading cause of irreversible vision impairment, emphasizing the critical need for early detection. Typically, AI-based glaucoma scree...

Enhancing Relation Extraction for COVID-19 Vaccine Shot-Adverse Event Associations with Large Language Models.

OBJECTIVE: The rapid evolution of the COVID-19 virus has led to the development of different vaccine shots, each designed to combat specific variants ...

Three-dimensional markerless surface topography approach with convolutional neural networks for adolescent idiopathic scoliosis screening.

Adolescent idiopathic scoliosis (AIS) is a three-dimensional lateral and torsional deformity of the spine, affecting up to 5% of the population. Tradi...

A novel flexible near-infrared endoscopic device that enables real-time artificial intelligence fluorescence tissue characterization.

Real-time endoscopic rectal lesion characterization employing artificial intelligence (AI) and near-infrared (NIR) imaging of the fluorescence perfusi...

Applying machine learning to predict bowel preparation adequacy in elderly patients for colonoscopy: development and validation of a web-based prediction tool.

BACKGROUND: Adequate bowel preparation is crucial for effective colonoscopy, especially in elderly patients who face a high risk of inadequate prepara...

Unraveling the power of NAP-CNB's machine learning-enhanced tumor neoantigen prediction.

In this study, we present a proof-of-concept classical vaccination experiment that validates the in silico identification of tumor neoantigens (TNAs) ...

Nano biosensor unlocks tumor derived immune signals for the early detection of ovarian cancer.

Ovarian cancer is a critical health issue for women nowadays. Its impact is significant because of its high mortality rate (324,603 worldwide), late-s...

Identification of Novel Fourth-Generation Allosteric Inhibitors Targeting Inactive State of EGFR T790M/L858R/C797S and T790M/L858R Mutations: A Combined Machine Learning and Molecular Dynamics Approach.

Targeted therapy with an allosteric inhibitor (AIs) is an important area of research in patients with epidermal growth factor receptor (EGFR) mutation...

Economics of AI and human task sharing for decision making in screening mammography.

The rising global incidence of breast cancer and the persistent shortage of specialized radiologists have heightened the demand for innovative solutio...

AI integrations with lung cancer screening: Considerations in developing AI in a public health setting.

Lung cancer screening implementation has led to expanded imaging of the chest in older, tobacco-exposed populations. Growing numbers of screening case...

Artificial intelligence for breast cancer screening in mammography (AI-STREAM): preliminary analysis of a prospective multicenter cohort study.

Artificial intelligence (AI) improves the accuracy of mammography screening, but prospective evidence, particularly in a single-read setting, remains ...