Preventive Care

Prediction of lipid nanoparticles for mRNA vaccines by the machine learning algorithm.

Lipid nanoparticle (LNP) is commonly used to deliver mRNA vaccines. Currently, LNP optimization primarily relies on screening ionizable lipids by traditional experiments which consumes intensive cost and time. Current study attempts to apply computational methods to accelerate the LNP development for mRNA vaccines. Firstly, 325 data samples of mRNA vaccine LNP formulations with IgG titer were coll...

Deep Learning-Based Sentiment Analysis of COVID-19 Vaccination Responses from Twitter Data.

The COVID-19 pandemic has had a devastating effect on many people, creating severe anxiety, fear, and complicated feelings or emotions. After the initiation of vaccinations against coronavirus, people's feelings have become more diverse and complex. Our aim is to understand and unravel their sentiments in this research using deep learning techniques. Social media is currently the best way to expre...

Comparative Study on the Efficacy of MF 59, ISA70 VG, and Nano-Aluminum Hydroxide Adjuvants, Alone and with Nano-Selenium on Humoral Immunity Induced by a Bivalent Newcastle+Avian Influenza Vaccine in Chickens.

Newcastle disease (ND) and Avian influenza (AI) are the major problems and the most economically important viral diseases in the poultry industry; the...

Deep neural network for video colonoscopy of ulcerative colitis: a cross-sectional study.

BACKGROUND: A combination of endoscopic and histological evaluation is important in the management of patients with ulcerative colitis. We aimed to ad...

Mild Adverse Events of Sputnik V Vaccine in Russia: Social Media Content Analysis of Telegram via Deep Learning.

BACKGROUND: There is a limited amount of data on the safety profile of the COVID-19 vector vaccine Gam-COVID-Vac (Sputnik V). Previous infodemiology s...

Development of a Machine learning image segmentation-based algorithm for the determination of the adequacy of Gram-stained sputum smear images.

BACKGROUND: Machine learning (ML) prepares and trains a model through supervised or unsupervised learning methods. Sputum, a respiratory tract secreti...

Machine Learning-based Voice Assessment for the Detection of Positive and Recovered COVID-19 Patients.

Many virological tests have been implemented during the Coronavirus Disease 2019 (COVID-19) pandemic for diagnostic purposes, but they appear unsuitab...

Factors That Influence Risk Perceptions and Successful COVID-19 Vaccination Communication Campaigns With American Indians.

COVID-19 vaccinations are the primary tool to end the pandemic. However, vaccine hesitancy continues to be a barrier to herd-immunity in the United St...

Breast Cancer Diagnosis by Convolutional Neural Network and Advanced Thermal Exchange Optimization Algorithm.

A common gynecological disease in the world is breast cancer that early diagnosis of this disease can be very effective in its treatment. The use of i...

COVID-19 Screening in Chest X-Ray Images Using Lung Region Priors.

Early screening of COVID-19 is essential for pandemic control, and thus to relieve stress on the health care system. Lung segmentation from chest X-ra...

Detection of colorectal lesions during colonoscopy.

Owing to its high mortality rate, the prevention of colorectal cancer is of particular importance. The resection of colorectal polyps is reported to d...

Evaluation of an Artificial Intelligence-Augmented Digital System for Histologic Classification of Colorectal Polyps.

IMPORTANCE: Colorectal polyps are common, and their histopathologic classification is used in the planning of follow-up surveillance. Substantial vari...

Virtual screening of dipeptidyl peptidase-4 inhibitors using quantitative structure-activity relationship-based artificial intelligence and molecular docking of hit compounds.

Dipeptidyl peptidase-4 (DPP-4) inhibitors are becoming an essential drug in the treatment of type 2 diabetes mellitus; however, some classes of these ...

Machine Learning-Based Single Cell and Integrative Analysis Reveals That Baseline mDC Predisposition Correlates With Hepatitis B Vaccine Antibody Response.

Vaccination to prevent infectious disease is one of the most successful public health interventions ever developed. And yet, variability in individual...

Machine Learning Assisted Approach for Finding Novel High Activity Agonists of Human Ectopic Olfactory Receptors.

Olfactory receptors (ORs) constitute the largest superfamily of G protein-coupled receptors (GPCRs). ORs are involved in sensing odorants as well as i...

A collaborative robotic solution to partly automate SARS-CoV-2 serological tests in small facilities.

The outbreak of COVID-19 has introduced a significant stress on the healthcare systems of many countries. The availability of quick and reliable scree...

Machine Learning for Workflow Applications in Screening Mammography: Systematic Review and Meta-Analysis.

Background Advances in computer processing and improvements in data availability have led to the development of machine learning (ML) techniques for m...

Can artificial intelligence replace ultrasound as a complementary tool to mammogram for the diagnosis of the breast cancer?

OBJECTIVE: To study the impact of artificial intelligence (AI) on the performance of mammogram with regard to the classification of the detected breas...

A Deep Learning Approach for Predicting Antigenic Variation of Influenza A H3N2.

Modeling antigenic variation in influenza (flu) virus A H3N2 using amino acid sequences is a promising approach for improving the prediction accuracy ...

Development and evaluation of a double-check support system using artificial intelligence in endoscopic screening for gastric cancer.

BACKGROUND: This study aimed to prevent missing gastric cancer and point out low-quality images by developing a double-check support system (DCSS) for...