Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Prospective pragmatic trial of automated retinal photography and AI glaucoma screening in Australian primary care.

There are no prospective clinical studies evaluating artificial intelligence implementation for glaucoma detection in real-world settings. We developed an automated retinal photography and AI-based screening system and prospectively assessed its accuracy, feasibility, and acceptability in Australian general practice (GP) clinics. Adults aged 50 years or older were recruited during routine GP visit...

Jul 1 2025 40595445

Improved convolutional neural network for precise exercise posture recognition and intelligent health indicator prediction.

This paper presents a novel framework for accurate exercise posture recognition and health indicator prediction based on improved convolutional neural networks. We propose a multi-scale feature fusion architecture incorporating spatiotemporal attention mechanisms to enhance key point detection precision while maintaining computational efficiency. The system achieves superior posture recognition pe...

Jul 1 2025 40595746
Machine learning and transformer models for prediction of postoperative pneumonia risk in patients with lower limb fractures.

Postoperative pneumonia, a prevalent complication arising from lower limb fracture surgery, can significantly prolong hospitalization periods and elev...

Jul 1 2025 40595785
Activated cancer-associated fibroblasts correlate with poor survival and decreased lymphocyte infiltration in infiltrative type distal cholangiocarcinoma.

Cancer-associated fibroblasts promote tumor progression through growth facilitation, invasion, and immune evasion. This study investigated the impact ...

Jul 1 2025 40596163
Deep learning-based dipeptidyl peptidase IV inhibitor screening, experimental validation, and GaMD/LiGaMD analysis.

BACKGROUND: Dipeptidyl peptidase-4 (DPP4) is considered a crucial enzyme in type 2 diabetes (T2D) treatment, targeted by inhibitors due to its role in...

Jul 1 2025 40597132
An explainable machine learning model for early warning of hypertensive and hypotensive anomalies in maintenance hemodialysis patients.

BACKGROUND: Intradialytic hypotension (IDH) and intradialytic hypertension (IDHTN) are major complications of maintenance hemodialysis (MHD) that sign...

Jul 1 2025 40597743
MCAUnet: a deep learning framework for automated quantification of body composition in liver cirrhosis patients.

Traditional methods for measuring body composition in CT scans rely on labor-intensive manual delineation, which is time-consuming and imprecise. This...

Jul 1 2025 40597795
Machine learning for detection of diffusion abnormalities-related respiratory changes among normal, overweight, and obese individuals based on BMI and pulmonary ventilation parameters: an observational study.

BACKGROUND: The integration of machine learning (ML) algorithms enables the detection of diffusion abnormalities-related respiratory changes in indivi...

Jul 1 2025 40598421
Transforming heart transplantation care with multi-omics insights.

Heart transplantation (HTx) remains the definitive treatment for patients with end-stage heart disease. Despite the number of HTx performed annually i...

Jul 1 2025 40598485
An MOF-Enhanced Anti-Fouling Immunoprobe Platform for Efficient Direct Screening of Pancreatic Cancer.

Monitoring biomarkers offers insights for early disease (e.g., cancer, chronic diseases) screening, treatment guidance and response evaluation. To tac...

Jul 1 2025 40598854
[Artificial intelligence in preventive medicine for children and adolescents-applications and acceptance].

The use of artificial intelligence (AI) in pediatric and adolescent medicine offers numerous possibilities, particularly in the prevention of chronic ...

Jun 30 2025 40586805
Metabolic Phenotypes, Genotypes, and Gut Microbiome Signatures in Obesity: Implications for Precision Nutrition Strategies in Type 2 Diabetes Prevention.

The worldwide prevalence of overweight and obesity has increased rapidly in the last decades. This rise has led to a surge in comorbidities such as ty...

Jun 30 2025 40587382
An intelligent screener for mild cognitive impairment via integrated eye-tracking and the digital clock drawing test.

BackgroundMild cognitive impairment (MCI) is a risk factor for dementia, and early screening is crucial for patient prognosis.ObjectiveTo construct an...

Jun 30 2025 40583783
Racial disparities in continuous glucose monitoring-based 60-min glucose predictions among people with type 1 diabetes.

Non-Hispanic white (White) populations are overrepresented in medical studies. Potential healthcare disparities can happen when machine learning model...

Jun 30 2025 40587474
Climate Change Impact on Human-Rodent Interfaces: Modeling Junin Virus Reservoir Shifts.

The drylands vesper mouse (Calomys musculinus) is the primary host for Junin mammarenavirus (JUNV), the etiological agent of Argentine hemorrhagic fev...

Jun 27 2025 40576885
A Responsible Framework for Assessing, Selecting, and Explaining Machine Learning Models in Cardiovascular Disease Outcomes Among People With Type 2 Diabetes: Methodology and Validation Study.

BACKGROUND: Building machine learning models that are interpretable, explainable, and fair is critical for their trustworthiness in clinical practice....

Jun 27 2025 40577645
Machine Learning Models Based on Enlarged Chemical Spaces for Screening Carcinogenic Chemicals.

Machine learning (ML) models for screening carcinogenic chemicals are critical for the sound management of chemicals. Previous models were built on sm...

Jun 27 2025 40579351
Identification of individuals who benefit from omega-3 fatty acid supplementation to prevent coronary heart disease: a machine-learning analysis of the VITAL.

Randomized controlled trials (RCTs) have demonstrated benefits of marine omega-3 polyunsaturated fatty acids (omega-3 FA) supplementation for the prev...

Jun 26 2025 40569483
In silico prediction of drug-induced cardiotoxicity with ensemble machine learning and structural pattern recognition.

Drug-induced cardiotoxicity poses a significant risk to human health, and reliable predictive models are needed for safety assessment. In this study, ...

Jun 26 2025 40569519
Predicting Retinal Nerve Fiber Layer Thickness From Ocular Hypertension Treatment Study Optic Disc Photographs.

IMPORTANCE: Deep learning predictions of retinal nerve fiber layer (RNFL) thickness derived from optic disc photographs may help to determine risk for...

Jun 26 2025 40569586
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