Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Showing 2741-2760 of 17,225 articles

Exploring hypoxia driven subtypes of pulmonary arterial hypertension through transcriptomics single cell sequencing and machine learning.

Pulmonary arterial hypertension (PAH) is a progressive cardiovascular disease characterized by elevated pulmonary arterial pressure, leading to right heart failure and death. Despite advancements in diagnosis and treatment, it remains incurable, and its mechanisms are poorly understood. This study aimed to integrate multi-omics data analysis and machine learning techniques to uncover the molecular...

Apr 24 2025 40275058

GDM-BC: Non-invasive body composition dataset for intelligent prediction of Gestational Diabetes Mellitus.

Gestational Diabetes Mellitus (GDM) refers to any degree of impaired glucose tolerance with onset or first recognition during pregnancy. As a high-prevalence disease, GDM damages the health of both pregnant women and fetuses in the short and long term. Accurate and cost-effective recognition of GDM is quite crucial to reduce the risk and economic pressure of this disease. However, existing dataset...

Apr 23 2025 40273822
Vascular-related biological stress, DNA methylation, allostatic load and domain-specific cognition: an integrated machine learning and causal inference approach.

BACKGROUND: Vascular disease in aging populations spans a wide range of disorders including strokes, circulation disorders and hypertension. As indivi...

Apr 23 2025 40269737
Testing the utility of GPT for title and abstract screening in environmental systematic evidence synthesis.

In this paper we show that OpenAI's Large Language Model (LLM) GPT perform remarkably well when used for title and abstract eligibility screening of s...

Apr 23 2025 40270055
Nuciferine activates intestinal TAS2R46 to attenuate metabolic disorders and hyperlipidemia via hepatic VLDL regulation.

BACKGROUND: Dysregulated blood lipid metabolism, a primary driver of hyperlipidemia, is closely associated with excessive very low-density lipoprotein...

Apr 22 2025 40311594
Recent advances in therapeutic probiotics: insights from human trials.

SUMMARYRecent advances in therapeutic probiotics have shown promising results across various health conditions, reflecting a growing understanding of ...

Apr 22 2025 40261032
A novel deep learning approach to classify 3D foot types of diabetic patients.

Diabetes mellitus is a worldwide epidemic that leads to significant changes in foot shape, deformities, and ulcers. Precise classification of diabetic...

Apr 22 2025 40258927
Advancing osteoarthritis research: the role of AI in clinical, imaging and omics fields.

Osteoarthritis (OA) is a degenerative joint disease with significant clinical and societal impact. Traditional diagnostic methods, including subjectiv...

Apr 22 2025 40263261
The clinical significance of an AI-based assumption model for neurocognitive diseases using a novel dual-task system.

Dual-task composed of gait or stepping tasks combined with cognitive tasks has been well-established as valuable tools for detecting neurocognitive di...

Apr 22 2025 40263361
Advancing personalized, predictive, and preventive medicine in bladder cancer: a multi-omics and machine learning approach for novel prognostic modeling, immune profiling, and therapeutic target discovery.

OBJECTIVE: This study aimed to identify and analyze immunogenic cell death (ICD)-related multi-omics features in bladder cancer (BLCA) using single-ce...

Apr 22 2025 40330458
Comparison of artificial intelligence-generated and physician-generated patient education materials on early diabetic kidney disease.

BACKGROUND: Diabetic kidney disease (DKD) is a common and serious complication of diabetes mellitus and has become the most important cause of end-sta...

Apr 22 2025 40331140
Detection and prevalence of avian influenza epidemic in the southwest of Poyang Lake and analysis of the influence of meteorological factors.

Recently, the epidemiological profile of avian influenza has changed dramatically worldwide. Avian influenza sampling and surveillance of wholesale an...

Apr 21 2025 40331080
Predicting Weight Loss Success After Gastric Sleeve Surgery: A Machine Learning-Based Approach.

BACKGROUND/OBJECTIVES: Obesity is a global health issue, and in this context, bariatric surgery is considered the most effective treatment for severe ...

Apr 21 2025 40284254
Bioinformatics Approach to Identifying Molecular Targets of Isoliquiritigenin Affecting Chronic Obstructive Pulmonary Disease: A Machine Learning Pharmacology Study.

To identify the molecular targets and possible mechanisms of isoliquiritigenin (ISO) in affecting chronic obstructive pulmonary disease (COPD) by regu...

Apr 21 2025 40332792
Bioanalysis of antihypertensive drugs by LC-MS: a fleeting look at the regulatory guidelines and artificial intelligence.

Hypertension is a multifaceted cardiovascular disease, a significant risk factor for stroke, heart attack, heart failure, and renal damage. An essenti...

Apr 21 2025 40256889
Enhancing medical AI with retrieval-augmented generation: A mini narrative review.

Retrieval-augmented generation (RAG) is a powerful technique in artificial intelligence (AI) and machine learning that enhances the capabilities of la...

Apr 21 2025 40343063
Computational modelling for risk assessment of neurological disorder in diabetes using Hodgkin-Huxley model.

BACKGROUND: Diabetes mellitus, characterized by chronic glucose dysregulation, significantly increases the risk of neurological disorders such as cogn...

Apr 20 2025 40287992
Coptidis rhizoma and berberine as anti-cancer drugs: A 10-year updates and future perspectives.

Cancer continues to be among the most substantial health challenges globally. Among various natural compounds, berberine, an isoquinoline alkaloid obt...

Apr 19 2025 40258505
A random forest-based predictive model for classifying BRCA1 missense variants: a novel approach for evaluating the missense mutations effect.

The right classification of variants is the key to pre-symptomatic detection of disease and conducting preventive actions. Since BRCA1 has a high inci...

Apr 18 2025 40251429
Diagnostic MicroRNA Signatures to Support Classification of Pulmonary Hypertension.

BACKGROUND: Patients with pulmonary hypertension (PH) are classified based on disease pathogenesis and hemodynamic drivers. Classification informs tre...

Apr 18 2025 40248872
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