Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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The association between clinically suspect arthralgia and adipokines in obese patients.

OBJECTIVE: Obesity is a moderate low-grade chronic inflammatory condition. The cause of low-grade inflammation in obese patients who have clinically suspect arthralgia (CSA) may be the subject of debate in clinical practice. Our aim is to determine whether inflammation is associated with obesity or rheumatic disease, and the association between leptin, chemerin, visfatin and inflammatory markers i...

Jan 1 2018 30641537

Overview of the Biological Activities of a Methanol Extract from Wild Red Belt Conk, Fomitopsis pinicola (Agaricomycetes), Fruiting Bodies from Central Italy.

Fomitopsis pinicola (Sw.) P. Karst. (Fomitopsidaceae) is a medicinal mushroom with a variety of healthy properties. In this study we tested the radical scavenging activity and antimicrobial and anticancer potential of methanol extracts of F. pinicola from central Italy. Molecular identification confirmed that the samples were F. pinicola; a Basic Local Alignment Search Tool search showed a close m...

Jan 1 2018 30806229
Circulating Monocyte Chemoattractant Protein-1 Levels and Lumbar Bone Mineral Density in Korean Women.

BACKGROUND: Monocyte chemoattractant protein-1 (MCP-1) is expressed in adipose tissue, macrophages, endothelial cells, and osteoblasts by parathyroid ...

Dec 30 2017 31089532
[Perioperative stroke effectively treated by an acute stroke team including anesthesia department: a case report].

Perioperative stroke is cerebral infarction occurring in the perioperative period. The incidence of perioperative stroke in non-cardiac, and non-neuro...

Dec 18 2017 29263488
Chronic Kidney Disease: Detection and Evaluation.

Chronic kidney disease affects 47 million people in the United States and is associated with significant health care costs, morbidity, and mortality. ...

Dec 15 2017 29431364
Prevalence and correlates of chronic kidney disease in a group of patients with hypertension in the Savanah zone of Cameroon: a cross-sectional study in Sub-Saharan Africa.

BACKGROUND: The prevalence of chronic kidney disease (CKD) is increasing worldwide due to an increase in the risk factors such as hypertension. The gr...

Dec 1 2017 29302463
Chemerin Blood Levels are Associated with MRI Measured Volumes of Abdominal Adipose Tissue Compartments and Lifestyle Choices.

Obesity is a low-grade chronic inflammatory state, in which a cytokine chemerin with its immunometabolic modulation has an important role. We aimed to...

Dec 1 2017 29590721
Metabolic acidosis of chronic kidney disease and subclinical cardiovascular disease markers: Friend or foe?

The effect of chronic metabolic acidosis (MA) on cardiovascular disease (CVD) in the setting of chronic kidney disease (CKD) is largely unknown. There...

Nov 1 2017 29381982
Enhancing Risk Assessment in Patients Receiving Chronic Opioid Analgesic Therapy Using Natural Language Processing.

OBJECTIVES: Clinical guidelines for the use of opioids in chronic noncancer pain recommend assessing risk for aberrant drug-related behaviors prior to...

Oct 1 2017 28034982
Adiponectin levels may help assess the clinical repercussions of obesity irrespective of body mass index.

OBJECTIVE: Adiponectin is the major product of adipose tissue. The aim of this study was to associate adiponectin levels with adipose tissue and metab...

Jul 1 2017 29278513
The World Health Organization Adult Attention-Deficit/Hyperactivity Disorder Self-Report Screening Scale for DSM-5.

IMPORTANCE: Recognition that adult attention-deficit/hyperactivity disorder (ADHD) is common, seriously impairing, and usually undiagnosed has led to ...

May 1 2017 28384801
Robotic pancreas transplantation in a type 1 diabetic patient with morbid obesity: A case report.

RATIONALE: Obesity is considered a relative contraindication to pancreas transplantation due to increased risks of wound-related complications. Roboti...

Feb 1 2017 28178127
Comparison of machine-learning algorithms to build a predictive model for detecting undiagnosed diabetes - ELSA-Brasil: accuracy study.

CONTEXT AND OBJECTIVE:: Type 2 diabetes is a chronic disease associated with a wide range of serious health complications that have a major impact on ...

Jan 1 2017 28746659
Machine Learning and Molecular Dynamics Based Insights into Mode of Actions of Insulin Degrading Enzyme Modulators.

BACKGROUND: Alzheimer's disease (AD) is one of the most common lethal neurodegenerative disorders having impact on the lives of millions of people wor...

Jan 1 2017 28137222
A Decision Support System for Cardiac Disease Diagnosis Based on Machine Learning Methods.

This paper proposes a decision support system for screening pediatric cardiac disease in primary healthcare centres relying on the heart sound time se...

Jan 1 2017 28423752
CD-KES: An Ontology Based Knowledge Education System for Patients with Chronic Diseases and Its Constructing Approach.

Patients' participation plays a crucial role in the management of chronic diseases. Educating patients about their diseases allows patients to self-re...

Jan 1 2017 29295289
Lactate levels and risk of lactic acidosis with metformin in diabetic kidney disease patients.

Metformin as an oral antidiabetic drug (OAD) is not recommended in renal failure due to the presumed risk of lactic acidosis though it has advantages ...

Jan 1 2017 29265047
Current state of continuous ambulatory peritoneal dialysis in Egypt.

Patients with end-stage renal disease (ESRD) continue to increase in number worldwide, especially in developing countries. Although continuous ambulat...

Jan 1 2017 29265049
Pattern and predictors of urine protein excretion among patients with type 2 diabetes attending a single tertiary hospital in Lagos, Nigeria.

Testing for proteinuria is used to screen for diabetic nephropathy. However, significant proportion of diabetics has normal urine protein excretion de...

Jan 1 2017 29265051
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