Latest AI and machine learning research in primary care for healthcare professionals.
OBJECTIVES: This study estimates the prevalence of wasting and examines associated factors among children aged 6-23 months in Ghana from a machine-learning perspective, with a particular focus on predicting new cases to inform preventive efforts. METHODS: This study is a secondary analysis of the 2022 Ghana Demographic and Health Survey, which includes 1506 children. Wasting status was assessed us...
Pseudomonas aeruginosa is a leading cause of nosocomial infections, particularly in individuals with a compromised immune system. Due to its strong adaptive ability, P. aeruginosa tends to develop antibiotic resistance and establish chronic infection, making its eradication through traditional antibiotics challenging. Thus, the development of novel therapeutic targets and corresponding inhibitors ...
BACKGROUND: Cancer remains a leading cause of morbidity worldwide. To reduce this burden, scalable, effective approaches are needed to address modifia...
INTRODUCTION: The rise in administrative burden on physicians is becoming increasingly recognised as a significant contributor to burnout and job diss...
Ageing heterogeneity hampers prevention and care. We used routine biochemical panels and unsupervised learning to identify latent phenotypes in commun...
Cyclosporine A (CsA) functions as a calcineurin inhibitor that perturbs T cell activation via calcineurin-nuclear factor of activated T cells (CaN-NFA...
BACKGROUND: Acute myeloid leukemia (AML) remains a therapeutic challenge due to chemoresistance and immunosuppression. This study aimed to discover no...
BACKGROUND: Head and neck cancer (HNC) is a common malignant tumor, and its treatment often leads to functional impairments in speech, swallowing, and...
BACKGROUND: Digital health technologies are fundamentally reshaping healthcare delivery, access, and governance worldwide. While these innovations off...
Two decades after its formalization, P4 medicine (predictive, preventive, personalized, participatory) remains more framework than practice. Most impl...
BACKGROUND: Diseases exist on spectra of risk factors, cellular perturbations, organ dysfunction, and clinical manifestations. It is unknown whether t...
INTRODUCTION: Healthcare professionals working in busy hospital environments are expected to make multiple back-to-back critical decisions related to ...
Anxiety disorders are common and impairing mental health conditions. Using data from 26,378 adults in the German National Cohort Study (NAKO), we inve...
The global prevalence of overweight and obesity is rising, and recent studies have established an independent contribution of adiposity to stroke risk...
BACKGROUND: Sleep disturbances and depressive symptoms frequently co-occur in older adults. Both conditions follow distinct, time-varying trajectories...
BACKGROUND: Early identification of childhood mental health disorders is a critical public health objective. Existing screening approaches, largely de...
PURPOSE: Wheelchair maintenance and repair services are critical for sustaining mobility, independence, and participation in daily activities. However...
OBJECTIVES: The pathophysiology of idiopathic intracranial hypertension (IIH) is poorly understood and disease-specific biomarkers are lacking. We aim...
UNLABELLED: Childhood obesity is rising globally. Yet, few studies have examined the microbiome and proteome in early childhood in relation to this ou...
PURPOSE: Neurocognitive and endocrine dysfunction are potential complications of cranial irradiation. However, risk factors are poorly understood, imp...