Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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AI-powered evaluation of dementia severity based on clinical data and visual scoring systems (MTA, ERICA, GCA) from MRI.

Dementia, particularly Alzheimer's disease (AD), is a growing concern in aging populations, with mild cognitive impairment (MCI) frequently progressing to AD. While existing studies often rely on comprehensive neuropsychological evaluations and assessments by neurologists and neuroradiologists, these approaches are not always feasible in routine or rural clinical practice. Current diagnostic metho...

May 11 2026 42115238

An exploratory study of multi-channel CNN for early detection of lung cancer from longitudinal healthcare records.

Lung cancer remains the leading cause of cancer-related mortality worldwide, with poor survival rates due to late-stage detection. Current low-dose computed tomography screening faces barriers including high costs and false-positive rates reaching 24%, while artificial intelligence offers opportunities to enhance early detection through longitudinal clinical data analysis. This study developed a M...

May 11 2026 42115281
Machine learning prediction for menopause women with low bone mass: a multicenter and retrospective study.

Early diagnosis of postmenopausal osteoporosis provides an opportunity to detect and prevent fractures. This study uses machine learning (ML) techniqu...

May 11 2026 42115688
[Artificial intelligence in pediatric ophthalmology: applications and perspectives].

Pediatric visual health is not only inextricably linked to an individual's lifelong cognitive development and quality of life, but also constitutes a ...

May 11 2026 42103673
Transforming hypoglycemia prediction in adult type 1 diabetes: a systematic review and meta-analysis for precision care.

Type 1 diabetes mellitus (T1DM) patients require lifelong insulin therapy; however, iatrogenic hypoglycemia remains a major clinical challenge, with h...

May 11 2026 42117040
Design and methodology of the AI-empowered Clinical Evidence for Integrated Chinese-Western Medicine (ACE-iMed) platform.

BACKGROUND: Integrated Chinese-Western medicine (ICWM) is a distinctive medical system that plays an important role in healthcare and has received inc...

May 10 2026 42293429
Machine learning and regional homogeneity reveal early and subtle brain changes in type 1 diabetes.

BACKGROUND AND PURPOSE: Type 1 diabetes mellitus (T1DM) usually begins early in life, and its development impacts brain functioning and cognitive proc...

May 10 2026 42119663
An artificial intelligence classifier as a screening tool to rule out otitis media in children.

OBJECTIVE: Acute otitis media is the most common bacterial infection among children and a significant global health burden. Despite its high incidence...

May 9 2026 42114455
Artificial intelligence-driven rational design and optimization of a potent terpenoid-derived PCSK9 inhibitor.

Hypercholesterolemia is a pivotal risk factor for cardiovascular diseases, and its effective management is critical to reducing cardiovascular event i...

May 9 2026 42105138
Clinician engagement shapes the impact of AI-based ECG screening for chronic liver disease in primary care.

Artificial intelligence (AI)-based screening tools show promise for early identification of chronic liver disease (CLD), yet their effectiveness in re...

May 9 2026 42106573
When to stop reviewing: validation of stop criteria in ASReview.

BACKGROUND: Systematic reviews are essential for evidence-based research, but they often require a great deal of time and effort. Although title and a...

May 9 2026 42106619
Digital phenotyping for predicting relapse in psychiatric disorders: a systematic review of passive sensing approaches.

BACKGROUND: Digital phenotyping - the moment-by-moment quantification of individual-level human behavior using data from personal digital devices - of...

May 9 2026 42106724
Molecular basis of precision nutrition: Food components, microbiome-derived metabolites, and multi-omics modeling.

Metabolic disorders, including obesity, type 2 diabetes, metabolic syndrome, and fatty liver disease, reflect multifactorial interactions among diet, ...

May 8 2026 42181960
Beyond the Mean: A Machine Learning-Based Trend Analysis of CGM Metrics for Improved HbA1C Estimation in Type 2 Diabetes.

BACKGROUND: Hemoglobin A1C (HbA1C) is the gold standard for assessing long-term glycemic control in people with diabetes. Increasing use of continuous...

May 8 2026 42100954
From Lumen to Myocardium With Artificial Intelligence: A Clinician's Guide to Comprehensive Cardiac CT.

Coronary artery disease assessment has long focused on stenosis severity, yet luminal narrowing alone fails to capture ischemic burden, plaque vulnera...

May 8 2026 42101950
Communication-Based Teaching on Childhood Obesity and the Planetary Health Diet in Medical Education: Proof-of-Concept Study Comparing 4 Information Sources.

BACKGROUND: Childhood obesity constitutes a complex medical and psychosocial challenge that requires both nutritional knowledge and sensitive, relatio...

May 8 2026 42102283
Machine Learning-Based Multidimensional Oximetry for Obstructive Sleep Apnea Screening: Development and External Validation.

BACKGROUND: Obstructive sleep apnea (OSA) affects nearly one billion people globally and poses a substantial public health threat. Effective and acces...

May 8 2026 42102385
Bridging survival analysis and machine learning to improve healthy life expectancy estimation using PHR records.

Healthy Life Expectancy (HLE) considers the years an individual has lived free of disease. Minimising time a population spends in ill-health will dire...

May 8 2026 42103899
Deep learning prediction of nocturnal hypertension for patients intolerant to ambulatory blood pressure monitoring.

BACKGROUND: Ambulatory blood pressure monitoring (ABPM) plays an irreplaceable role in the diagnosis and management of hypertension. However, more tha...

May 8 2026 42103941
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