Latest AI and machine learning research in primary care for healthcare professionals.
Detecting water leakage represents a significant and pervasive challenge in water supply systems due to the complexity of network behavior, and the diversity of leakage manifestations, which may remain undetected. The magnitude of leakage varies considerably, from 3% to over 50%, depending on the level of maintenance undertaken. The global volume of water loss per year is estimated to be 126 billi...
Circulating cell-free DNA (cfDNA) has emerged as a valuable non-invasive biomarker that provides unique insights into the spatial and temporal heterogeneity of tumors, serving a key role in cancer precision medicine. Applications of cfDNA include detecting disease progression before clinical and radiological confirmation, identifying actionable genomic alterations, monitoring treatment response, r...
BACKGROUND: In individuals with normal body weight, altered fat distribution contributes to metabolic dysfunction and hepatic steatosis. We hypothesiz...
BACKGROUND: Despite low-molecular-weight heparin (LMWH) prophylaxis, the incidence of deep vein thrombosis (DVT) remains high in intensive care unit (...
INTRODUCTION: Artificial intelligence (AI), particularly large-language models like Chat Generative Pre-Trained Transformer (ChatGPT), has demonstrate...
BACKGROUND: Rare diseases affect more than 300 million people globally, and only about 5% have approved therapies. Lysosomal storage disorders (LSDs) ...
Cardiovascular disease (CVD) remains a leading global health threat, responsible for one in five deaths worldwide. Early detection is critical to miti...
Type 2 diabetes mellitus (T2DM) requires multi-target therapeutic approaches addressing both insulin resistance and insulin secretion deficits. Althou...
OBJECTIVE: The aim of this scoping review was to systematically identify and map the literature on statistical and mathematical approaches used to est...
Modern cardiology is entering a phase where improving the prevention, diagnosis, and treatment of cardiovascular diseases (CVD) necessitates a deeper ...
Skin aging reflects both intrinsic biological decline and extrinsic influences collectively known as the skin exposome, including ultraviolet (UV) rad...
IMPORTANCE: Retinopathy of prematurity (ROP) screening requires frequent examinations to avoid missed treatment-requiring disease, but this approach i...
OBJECTIVES: To investigate the association between quantitative retinal vascular parameters and coronary artery disease (CAD) and to evaluate the effi...
Linagliptin, a DPP-4 inhibitor commonly used in the management of diabetes mellitus, has shown potential activity in polycystic ovary syndrome (PCOS)....
Diabetes mellitus is a long-term metabolic condition that develops when the body cannot produce insulin effectively or use it properly. Individuals us...
Pulmonary hypertension (PH) is a severe and oftentimes fatal disease with a high degree of clinical variability. Its complexity necessitates a multifa...
BACKGROUND AND AIMS: The identification of prefrailty, a reversible state of vulnerability in older adults, remains a clinical challenge. Arterial sti...
OBJECTIVE: A significant residual risk of myocardial infarction (MI) persists in hypertensive patients treated with angiotensin receptor blockers (ARB...
Early identification of cardiometabolic and autonomic dysfunction using electrocardiogram (ECG) signals is essential for preventive cardiovascular scr...
INTRODUCTION: The CRISPR/Cas system has emerged as a highly versatile platform for diagnosing infectious diseases, particularly viral pathogens. Human...