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Preliminary findings on a deep learning model using electroencephalogram for multi-level neuropathic pain detection in post-stroke patients.

AIM: Neuropathic pain occurs commonly after stroke and represents a major source of disability for affected patients. This study aims to develop an accurate and computationally efficient framework for multi-level neuropathic pain detection using electroencephalography signals. METHODS: A Quantum-Inspired Pyramid Depthwise Separable Residual Network is proposed, which integrates three innovations: ...

Nov 24 2025 41199478

Deep learning-based image reconstruction significantly improves image quality of MRI examinations of the orbit at 3 Tesla.

PURPOSE: The purpose of this study was to assess the benefit of a deep learning-based image reconstruction (DLBIR) for improving image quality in orbital magnetic resonance imaging (MRI) at 3 Tesla (T). MATERIALS AND METHODS: Seventy-one patients (48 women and 23 men) with a mean age of 52 ± 19.5 (standard deviation [SD]) years (age range: 7-90 years) who underwent MRI examination of the orbit at ...

Nov 23 2025 41276422
Reveal a risk and potential mechanism for keratoconus progression with isotretinoin: Toxicogenomic, transcriptomics and real-world evidence insights.

PURPOSE: Limited clinical data and unstable animal models hinder understanding isotretinoin-induced keratoconus. We addressed this by integrating phar...

Nov 22 2025 41285218
AI in healthcare: mapping Romania's transition from research to intellectual property & industry solutions.

OBJECTIVES: Romania is aligning its healthcare AI ecosystem with the European Union's AI Act (2024/1689), through its own National AI Strategy. Despit...

Nov 20 2025 41258945
Proactive and privacy-Preserving defense for DNS over HTTPS via federated AI attestation (PAFA-DoH).

DNS over HTTPS(DoH) improves privacy but still admits tunneling, resolver manipulation, and side-channel leakage. We present PAFA-DoH, a practical def...

Nov 19 2025 41297208
Utility and limitations of the FDA adverse events reporting system public dashboard for safety analyses: a case study with vesicular monoamine transporter 2 inhibitors.

INTRODUCTION: The United States Food and Drug Administration (FDA) requires post-marketing surveillance of approved drugs, and pharmaceutical manufact...

Nov 17 2025 41212745
AI landmark versus conventional ultrasound-guided injections for adhesive capsulitis: a prospective, propensity score-matched, superiority study.

AIM: To investigate the artificial Intelligence (AI) landmark for guiding rotator cuff interval injections for adhesive capsulitis (AC). MATERIAL AND ...

Nov 11 2025 41217760
The Development and Validation of Multivariable Electronic Health Record-Based Models to Predict Diabetic Ketoacidosis-Related Hospitalizations for Adults with Type 1 Diabetes.

AIM: To develop and validate models that use electronic health record (EHR) data to predict diabetic ketoacidosis (DKA)-related hospitalizations over ...

Nov 7 2025 41556335
Deep learning-based combined noise reduction and contrast enhancement for post-neoadjuvant pancreatic cancer CT: does improved image quality translate to better resectability assessment?

PURPOSE: To evaluate whether deep learning-based combined noise reduction and contrast enhancement reconstruction (DLR) improves image quality and res...

Nov 4 2025 41186714
Transcription Accuracy of Automatic Speech Recognition for Orthodontic Clinical Records.

Accurate clinical records are fundamental to dental practice. Automatic speech recognition (ASR) has the capacity to convert spoken clinical language ...

Nov 3 2025 41178647
Achieving faithful explainability in feedforward neural networks through accurately computed feature attribution.

The rapid advancements in machine learning have led to the deployment of complex models in critical domains such as healthcare, finance, and autonomou...

Nov 3 2025 41240598
Impact of hypotension prediction index-guided management on intraoperative hypotension and postoperative outcomes in abdominal surgery: A meta-analysis of randomized controlled trials.

BACKGROUND: The Hypotension Prediction Index (HPI) is a machine-learning algorithm designed to predict hypotension. by maintaining mean arterial press...

Oct 30 2025 41175934
Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer's disease: evidence from multi-cohort analysis.

BACKGROUND: The rapid increase in the incidence of Alzheimer's disease (AD) has raised concerns, given its profound effects on both society and the ec...

Oct 30 2025 41168076
An Interpretable Machine Learning Model for Early Multitemporal Prediction of Onset of Acute Kidney Injury in Intensive Care Unit Patients with Severe Trauma.

Background: Acute Kidney Injury (AKI), a leading organ failure cause in critical patients, demands early high-risk identification to enhance outcomes....

Oct 29 2025 41160504
Multidimensional quantification of pain responses using novel rat pain scale reveals the absence of opioid induced hyperalgesia following chronic contingent and non-contingent morphine exposure in rats.

Opioids are often prescribed to treat chronic and post-operative pain, but there is data to suggest that opioid exposure can lead to hyperalgesia or a...

Oct 27 2025 41161353
Strengthening Signal Detection in Pharmacovigilance by Using International Nonproprietary Name (INN) Stems.

'Stems', which mark pharmacological relationships between substances, form the backbone of the International Nonproprietary Name (INN) system, develop...

Oct 25 2025 41138033
Comparing the Effectiveness of a Robotic and Dynamic Navigation System in Fiber Post removal: An In Vitro Study.

INTRODUCTION: This in vitro study evaluated the effectiveness of a robotic system (RS) and dynamic navigation system (DNS) compared with the freehand ...

Oct 24 2025 41236008
GPT-4o in Nutrition for Inpatients Undergoing Post-Stroke Rehabilitation: Identifying Dietary Errors, Exploring Expert-AI Rationale Differences, and Structuring AI-Expert Collaboration.

OBJECTIVE: Inpatients undergoing stroke rehabilitation experience high malnutrition rates, requiring strict dietary management. However, manual and ti...

Oct 15 2025 41091021
A data-driven modeling approach to prediction of persistent foot drop after gastroc-soleus lengthening surgery in children with cerebral palsy.

BACKGROUND: Gastrocsoleus lengthening (GSL) is an established surgical intervention for equinus deformity in children with cerebral palsy (CP). While ...

Oct 14 2025 41223483
Artificial Intelligence-Based Algorithms Improve Care of Patients with AAA.

BACKGROUND: Timely detection and monitoring of abdominal aortic aneurysms (AAAs) are necessary to prevent ruptures and decrease mortality. Artificial ...

Oct 6 2025 41061923
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