Infectious Disease

Public Health

Latest AI and machine learning research in public health for healthcare professionals.

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Utilizing Machine Learning to Improve Neutralization Potency of an HIV-1 Antibody Targeting the gp41 N-Heptad Repeat.

The N-heptad repeat (NHR) of the HIV-1 gp41 prehairpin intermediate (PHI) is an attractive potential vaccine target with high sequence conservation across diverse strains. However, despite the potency of NHR-targeting peptides and clinical efficacy of the NHR-targeting entry inhibitor enfuvirtide, no potently neutralizing NHR-directed monoclonal antibodies (mAbs) nor antisera have been identified ...

Jun 20 2025 40540236

Cancer vaccines and the future of immunotherapy.

Vaccines have had a major impact on the control of infectious disease, most recently by helping to combat the COVID-19 pandemic. Prophylactic cancer vaccines have prevented several malignancies by protecting against cancer-causing pathogens. By contrast, therapeutic vaccines training the immune system to eliminate established tumours are now showing real promise in clinical settings. In the adjuva...

Jun 18 2025 40541217
Changes in Epidemiological Characteristics of Varicella and Breakthrough Cases in Ningbo, China, From 2010 to 2023: Surveillance Study.

BACKGROUND: Varicella is a prevalent respiratory infectious disease. Continuous monitoring is essential to understand evolving epidemiological pattern...

Jun 18 2025 40533066
Does the registration system reform reduce the finance sector's risk spillover effect in China's stock market-Causal inference based on dual machine learning.

With growing uncertainty in global trade, improving access to domestic capital markets has become an important way to manage financial risk spillovers...

Jun 18 2025 40531819
Identifying Risk Factors of Substance Use in Finland: A Machine Learning Approach.

: This study explores the dynamics of substance use in Finland, employing Artificial Intelligence (AI) and Machine Learning techniques to identify key...

Jun 16 2025 40522359
Advancing AMR Surveillance: Confluence of One Health and Big Data Integration : Converging One Health and Big Data for AMR.

Antibiotic resistance poses a critical global health threat, demanding robust surveillance systems to monitor its prevalence, patterns, and trends. Th...

Jun 16 2025 40522529
Measurement, Characterization, and Mapping of COVID-19 Misinformation in Spain: Cross-Sectional Study.

BACKGROUND: The COVID-19 pandemic has been accompanied by an unprecedented infodemic characterized by the widespread dissemination of misinformation. ...

Jun 16 2025 40523274
Analysis of disease severity and mortality prediction using machine learning during COVID-19.

This paper focuses on how machine learning (ML) algorithms and applications have been used to analyze disease severity and mortality prediction in COV...

Jun 14 2025 40517610
Rapid prediction of antibiotic resistance in complex using whole-genome and metagenomic sequencing.

Clinical management and surveillance of the complex (ECC) face significant challenges due to inaccurate species identification and prolonged turnarou...

Jun 12 2025 40503893
Clinical decision tree for optimising endoscopic assessment of signet ring cell carcinoma in hereditary diffuse gastric cancer surveillance.

Background and study aims Prophylactic total gastrectomy (PTG) is the definitive treatment for hereditary diffuse gastric cancer syndrome (HDGC). Endo...

Jun 12 2025 40506018
Predictive Stability in Biopharmaceuticals and Vaccines: Perspectives and Recommendations Towards Accelerating Patient Access.

The perspective review discusses predictive stability computational modeling and scientific risk-based approaches to prospectively assess long-term st...

Jun 12 2025 40516695
Automated identification of serotype using MALDI-TOF mass spectrometry and machine learning techniques.

UNLABELLED: serotyping is essential for epidemiological studies and clinical treatment guidance. However, traditional serological agglutination metho...

Jun 11 2025 40497731
Challenges and Opportunities for Global Cervical Cancer Elimination: How Can We Build a Model for Other Cancers?

Cervical cancer remains a leading cause of cancer-related death among women globally, despite the availability of effective prevention through human p...

Jun 11 2025 40499075
Bayesian optimization and machine learning for vaccine formulation development.

Developing vaccines with a better stability is an area of improvement to meet the global health needs of preventing infectious diseases. With the adva...

Jun 11 2025 40498693
Use of deep learning-based NLP models for full-text data elements extraction for systematic literature review tasks.

Systematic literature review (SLR) is an important tool for Health Economics and Outcomes Research (HEOR) evidence synthesis. SLRs involve the identif...

Jun 3 2025 40461545
Evaluating sentiment analysis models: A comparative analysis of vaccination tweets during the COVID-19 phase leveraging DistilBERT for enhanced insights.

This study investigates public sentiment toward COVID-19 vaccinations by analyzing Twitter data using advanced machine learning (ML) and natural langu...

May 30 2025 40529516
Hotspots and Trends in Research on Early Warning of Infectious Diseases: A Bibliometric Analysis Using CiteSpace.

Emerging and re-emerging infectious diseases (EIDs and Re-EIDs) cause significant economic crises and public health problems worldwide. Epidemics app...

May 29 2025 40508906
Future Perspectives of Liver Research in the Asia-Pacific Region: Focus on Hepatitis B and C.

The Asia-Pacific region faces serious liver health challenges, primarily because of the comparatively high prevalence of hepatitis B virus (HBV) and h...

May 27 2025 40423265
Can ChatGPT Counter Vaccine Hesitancy? An Evaluation of ChatGPT's Responses to Simulated Queries from the General Public.

Vaccines have eradicated deadly diseases, yet vaccine hesitancy persists, leading to reduced uptake. Some individuals, mistrustful of healthcare prov...

May 27 2025 40508882
Deep learning architectures for influenza dynamics and treatment optimization: a comprehensive review.

As a major worldwide health concern, influenza still requires precise modeling of flu dynamics and efficient treatment approaches. Deep learning archi...

May 27 2025 40495931
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