Public Health

From molecular mechanisms to digital surveillance: the 2010-2025 evolution of benzodiazepine and Z-drug misuse research.

The misuse of benzodiazepines (BZDs) and Z-drugs poses significant global public health challenges. This study maps the scientific evolution and paradigm shifts in this field from 2010 to 2025. A bibliometric analysis of 6,311 publications from the Web of Science Core Collection was performed using VOSviewer and CiteSpace to identify collaboration networks, research hotspots, and emerging frontier...

Digital Conversation Companions.

Advances in voice recognition and artificial intelligence (AI) could soon yield digital conversation companions-software that combines conversational AI with health monitoring and promotion. We describe how this technology, once developed and deployed, could transform the way older adults age and receive care. By obviating the need to read or type, the software could be used by individuals with re...

A computational method to design broad-spectrum T cell-inducing vaccines applied to Betacoronaviruses.

Antigenically diverse pathogens such as coronaviruses pose substantial global health threats, highlighting the need for broad-spectrum vaccines. Here,...

Pathogenic Significance of Trypanosomatids: Progress in Drug Resistance, Control Strategies, and Artificial Intelligence.

Trypanosomatids, including the genera Trypanosoma and Leishmania, are protozoan parasites of significant medical and veterinary relevance. These organ...

CIST: A clade-informed sequence transformer framework for predicting influenza virus antigenicity.

Rapid antigenic evolution of influenza viruses complicates timely vaccine strain selection and renders prospective interpretation of serological assay...

Tephritid26: A standardized, multi-angle image dataset of quarantine-significant true fruit flies for deep learning-based identification.

Accurate and rapid identification of quarantine-significant tephritids is critical to global agricultural biosecurity, but the application of deep lea...

Spatiotemporal genomic analysis and risk assessment of the plasmids carrying blaOXA-48-like genes based on a large-scale international dataset.

BACKGROUND: The spread of OXA-48-like carbapenemases represents a major public health challenge. Although previous studies have investigated OXA-48-li...

Augmenting Pediatric Care With Artificial Intelligence: Opportunities and Responsibilities for Nurse Practitioners.

BACKGROUND: Artificial intelligence (AI) is emerging as a critical tool for nurse practitioners delivering pediatric and adolescent and young adult (A...

Automated Identification of Surgical Site Infections From Electronic Medical Records: Retrospective Observational Predictive Modeling Study.

BACKGROUND: Surgical site infections (SSIs) affect 160,000 to 300,000 patients annually, increasing postoperative mortality, causing significant compl...

Neural networks and behavioral frameworks to analyse the impact of media and individual awareness for controlling epidemics.

Enhancing individual awareness and immunization are generally recognized as fundamental strategies for controlling infectious diseases. Awareness is i...

Rational design of an optimized ferritin nanoparticle vaccine targeting both SARS-CoV-2 and MERS-CoV.

BACKGROUND: Coronaviruses including SARS-CoV-2 and MERS-CoV remain threats to global health. Ferritin nanoparticle-based vaccines are promising platfo...

Artificial intelligence-based prediction of diseases among homeless populations in Bogotá: Implications for targeted interventions.

BACKGROUND: The homeless population in Bogotá exhibits complex social and health vulnerabilities, with a high prevalence of chronic and communicable d...

Review Article: Advances in the Diagnosis of Dysplasia in Barrett's Oesophagus.

BACKGROUND: Barrett's oesophagus (BE), the precursor to oesophageal adenocarcinoma, progresses through a stepwise dysplastic sequence. Accurate dyspla...

The evolving landscape of acute kidney injury: research directions and changes in clinical practice.

Acute kidney injury (AKI) is a common and serious disease, needing a comprehensive and management-based approach. While traditional practice focused o...

Translational applications of artificial intelligence and machine learning for mosquito-borne disease control in low- and middle-income countries.

OBJECTIVES: To synthesize evidence on the application of artificial intelligence (AI) and machine learning (ML) for mosquito-borne disease (MBD) contr...

Protocols for genomic epidemiology and source attribution of enteric bacteria causing diarrhoeal disease across Africa.

INTRODUCTION: Enteric bacterial pathogens are a major cause of diarrhoeal disease in low-income and middle-income countries, with complex transmission...

A fractional ABC model for hepatitisB virus transmission with forecasting of epidemic trends using neural networks.

This paper develops a fractional-order HBV epidemic model using the Atangana-Baleanu-Caputo (ABC) fractional derivative with a nonsingular Mittag-Leff...

A bibliometric analysis of research trends and future directions in early detection of pancreatic cancer.

BACKGROUND: Research on the early detection of pancreatic cancer has grown rapidly in recent years; however, existing bibliometric studies in this fie...

Cardiac substructure dosimetry in thoracic radiotherapy: moving beyond mean heart dose and toward precision cardiac risk mitigation.

BACKGROUND: Radiation-induced heart disease (RIHD) remains a clinically significant consequence of thoracic radiotherapy (RT). Historically, the mean ...

Predictive Modeling of Enterovirus Hospital Burden Using Machine Learning and Age-Specific Surveillance Data: Operational Forecasting in Taiwan During the Postpandemic Era.

BACKGROUND: Enterovirus infections cause substantial pediatric morbidity worldwide, with severe cases requiring hospitalization. Accurate forecasting ...