Pulmonology

Aging at the Crossroads of Organ Interactions: Implications for the Heart.

Aging processes underlie common chronic cardiometabolic diseases such as heart failure and diabetes. Cross-organ/tissue interactions can accelerate aging through cellular senescence, tissue wasting, accelerated atherosclerosis, increased vascular stiffness, and reduction in blood flow, leading to organ remodeling and premature failure. This interorgan/tissue crosstalk can accelerate aging-related ...

Influence of content-based image retrieval on the accuracy and inter-reader agreement of usual interstitial pneumonia CT pattern classification.

OBJECTIVES: To investigate whether a content-based image retrieval (CBIR) of similar chest CT images can help usual interstitial pneumonia (UIP) CT pattern classifications among readers with varying levels of experience.

Apnea detection using wrist actigraphy in patients with heterogeneous sleep disorders.

Obstructive sleep apnea (OSA) and related hypoxia are well-established cardiovascular and neurocognitive risk factors. Current multi-sensor diagnostic...

Deep Learning-Based Multimodal Feature Interaction-Guided Fusion: Enhancing the Evaluation of EGFR in Advanced Lung Adenocarcinoma.

RATIONALE AND OBJECTIVES: The aim of this study is to develop a deep learning-based multimodal feature interaction-guided fusion (DL-MFIF) framework t...

Meta-analysis of shotgun sequencing of gut microbiota in obese children with MASLD or MASH.

Alterations in the gut microbiome affect the development and severity of metabolic dysfunction-associated steatotic liver disease (MASLD) or metabolic...

AI-enhanced computational discovery of promising ALK5 inhibitors in a ultra-large chemical space library for cardiovascular Disease therapy.

Cardiac fibrosis, characterized by excessive extracellular matrix deposition, is a critical contributor to cardiovascular diseases, including heart fa...

Lung MRI: Indications, Capabilities, and Techniques- Expert Panel Narrative Review.

Lung MRI provides both structural and functional information across a spectrum of parenchymal and airway pathologies. MRI, using current widely availa...

ÆMMamba: An Efficient Medical Segmentation Model With Edge Enhancement.

Medical image segmentation is critical for disease diagnosis, treatment planning, and prognosis assessment, yet the complexity and diversity of medica...

Imbalanced feature generation based on bootstrap power spectral curve for estimating respiratory rate.

Rapid respiratory rate (RR) changes in older adults may indicate serious illness. Therefore, accurately estimating RR for cardiorespiratory fitness is...

Arginine methylation patterns in LUAD: defining prognostic subtypes and relevance to immunotherapy.

BACKGROUND: Lung cancer remains the leading cause of cancer-related death worldwide, with lung adenocarcinoma (LUAD) being the most common subtype. Ar...

Metabolic signature of COVID-19 progression: potential prognostic markers for severity and outcome.

INTRODUCTION: There are significant challenges remain in accurately categorizing the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV...

Clinical relevance of computationally derived tubular features and their spatial relationships with the interstitial microenvironment in minimal change disease/focal segmental glomerulosclerosis.

BACKGROUND: Visual scoring of tubular damage has limitations in capturing the full spectrum of structural changes and prognostic potential. Here, we i...

A Comprehensive Dataset for Activity of Daily Living (ADL) Research Compiled by Unifying and Processing Multiple Data Sources.

: Activities of Daily Living (ADLs) are essential tasks performed at home and used in healthcare to monitor sedentary behavior, track rehabilitation t...

Prognostic effect of CD74 and development of a radiomic model for predicting CD74 expression in non-small cell lung cancer.

BACKGROUND: The classical prognostic indicators of lung cancer are no longer sufficient for prognostic stratification and individualized treatment of ...

Cross-species AI: shifting a convolutional neural network from pigs to lambs to detect pneumonia at slaughter.

Abattoir-based data are widely regarded as suitable tools to estimate farm animals' health and welfare during the entire lifecycles. However, the syst...

Imaging patterns and recommendations for diagnosis, staging, and management of lung cancer.

Lung cancer is the second most commonly diagnosed cancer worldwide. In the present era of targeted therapy for various lung cancer mutations, it is es...

Constructing Built-In Electric Field in Hierarchical-Flower Heterostructure for High-Performance Serum Metabolic Assay.

Laser desorption ionization mass spectrometry (LDI-MS) is a critical platform for high-throughput nontargeted metabolomics analysis in clinical diagno...

Label-Free and Intelligent Cell Death Recognition Toward Lung Cancer Chemotherapy.

The lack of high-throughput, label-free, and intelligent recognition models for assessing cell death hinders the broad application of cell death analy...

Fusing radiomics and deep learning features for automated classification of multi-type pulmonary nodule.

BACKGROUND: The accurate classification of lung nodules is critical to achieving personalized lung cancer treatment and prognosis prediction. The trea...

Early Prediction of Mortality Risk in Acute Respiratory Distress Syndrome: Systematic Review and Meta-Analysis.

BACKGROUND: Acute respiratory distress syndrome (ARDS) is a life-threatening condition associated with high mortality rates. Despite advancements in c...