Pulmonology

Molecular mechanisms of suberoylanilide hydroxamic acid in the inhibition of TGF-β1-mediated canine corneal fibrosis.

OBJECTIVE: To investigate molecular mechanisms mediating anti-fibrotic effect of SAHA in the canine cornea using an in vitro model. We hypothesized that SAHA attenuates corneal fibrosis by modulating Smad-dependent and, to a lesser extent, Smad-independent signaling pathways activated by TGF-β1, as well as matrix metalloproteinase (MMP) activity.

Comparison of emergence after deep extubation using desflurane or desflurane with remifentanil in patients undergoing general anesthesia: a randomized trial.

STUDY OBJECTIVE: To compare recovery times and respiratory complications during emergence after deep extubation using either desflurane alone or a lower concentration of desflurane with remifentanil.

Diagnosing childhood pulmonary tuberculosis using a single sputum specimen on Xpert MTB/RIF at point of care.

BACKGROUND: The GeneXpertMTB/RIF (Cepheid, USA) (Xpert) has proved successful for pulmonary tuberculosis (TB) diagnosis on decontaminated/concentrated...

Neutrophil Elastase Inhibitor Following Liver Resection: A Matched Cohort Study.

BACKGROUND: Sivelestat is a neutrophil elastase inhibitor (NEI) with positive impact on the respiratory complications in thoracic surgery. Based on th...

Incidence of nonresponse and individual patterns of response following sprint interval training.

The current study sought to explore the incidence of nonresponders for maximal or submaximal performance following a variety of sprint interval traini...

Toward Standardized Acoustic Radiation Force (ARF)-Based Ultrasound Elasticity Measurements With Robotic Force Control.

OBJECTIVE: Acoustic radiation force (ARF)-based approaches to measure tissue elasticity require transmission of a focused high-energy acoustic pulse f...

Modulatory role of garlicin in migration and invasion of intrahepatic cholangiocarcinoma via PI3K/AKT pathway.

Increasing evidences have indicated the role of garlicin in inhibiting the progression of various tumors including glioma, pulmonary carcinoma and pan...

Circulating Aldosterone Levels and Disease Severity in Pulmonary Arterial Hypertension.

OBJECTIVES: It is not known whether aldosterone levels are associated with increased mortality in patients with pulmonary arterial hypertension (PAH)....

Neural hypernetwork approach for pulmonary embolism diagnosis.

BACKGROUND: Hypernetworks are based on topological simplicial complexes and generalize the concept of two-body relation to many-body relation. Further...

Characteristics of pellets with immobilized activated sludge and its performance in increasing nitrification in sequencing batch reactors at low temperatures.

Immobilized pellets obtained by means of entrapping activated sludge in waterborne polyurethane were successfully adapted in ammonium (NH4(+)-N) synth...

Relationship between obstructive sleep apnea cardiac complications and sleepiness in children with Down syndrome.

OBJECTIVE/BACKGROUND: Children with Down syndrome (DS) have a high rate of pulmonary hypertension and sleepiness. They also have a high prevalence of ...

Ginsenoside Rg1 Improves In vitro-produced Embryo Quality by Increasing Glucose Uptake in Porcine Blastocysts.

Ginsenoside Rg1 is a natural compound with various efficacies and functions. It has beneficial effects on aging, diabetes, and immunity, as well as an...

Pain Intensity Recognition Rates via Biopotential Feature Patterns with Support Vector Machines.

BACKGROUND: The clinically used methods of pain diagnosis do not allow for objective and robust measurement, and physicians must rely on the patient's...

Perioperative pulmonary complications in obese patients undergoing robotic procedures for gynecological cancers.

Measuring oxygen levels in Caco-2 cultures.

PURPOSE: Measuring oxygen levels in three different systems of Caco-2 cell culture.

Real alerts and artifact classification in archived multi-signal vital sign monitoring data: implications for mining big data.

Huge hospital information system databases can be mined for knowledge discovery and decision support, but artifact in stored non-invasive vital sign (...

Detecting Lung Diseases from Exhaled Aerosols: Non-Invasive Lung Diagnosis Using Fractal Analysis and SVM Classification.

BACKGROUND: Each lung structure exhales a unique pattern of aerosols, which can be used to detect and monitor lung diseases non-invasively. The challe...

Capnodynamic assessment of effective lung volume during cardiac output manipulations in a porcine model.

A capnodynamic calculation of effective pulmonary blood flow includes a lung volume factor (ELV) that has to be estimated to solve the mathematical eq...

Synbiotic enhances immune responses against infectious bronchitis, infectious bursal disease, Newcastle disease and avian influenza in broiler chickens.

Increased susceptibility of birds to avian pathogens in intensive husbandry system has emphasized on necessity of improvement of innate and specific i...

Influence of recovery intensity on oxygen demand and repeated sprint performance.

BACKGROUND: This study aimed to determine effects of recovery intensity (passive, 20%, 30% and 40% V̇O2peak) on oxygen uptake kinetics, performance an...