Rheumatology

Latest AI and machine learning research in rheumatology for healthcare professionals.

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Ultrasensitive Anti-Interference Voice Recognition by Bio-Inspired Skin-Attachable Self-Cleaning Acoustic Sensors.

Human voice recognition systems (VRSs) are a prerequisite for voice-controlled human-machine interfaces (HMIs). In order to avoid interference from unexpected background noises, skin-attachable VRSs are proposed to directly detect physiological mechanoacoustic signals based on the vibrations of vocal cords. However, the sensitivity and response time of existing VRSs are bottlenecks for efficient H...

Nov 11 2019 31687810

The feasibility of developing biomarkers from peripheral blood mononuclear cell RNAseq data in children with juvenile idiopathic arthritis using machine learning approaches.

BACKGROUND: The response to treatment for juvenile idiopathic arthritis (JIA) can be staged using clinical features. However, objective laboratory biomarkers of remission are still lacking. In this study, we used machine learning to predict JIA activity from transcriptomes from peripheral blood mononuclear cells (PBMCs). We included samples from children with Native American ancestry to determine ...

Nov 9 2019 31706344
White blood cells detection and classification based on regional convolutional neural networks.

White blood cells (WBC) are important parts of our immune system and they protect our body against infections by eliminating viruses, bacteria, parasi...

Nov 4 2019 31760248
[Chances of Artificial Intelligence and Big Data for the Diagnosis and Treatment of Age-related Macular Degeneration].

Age-related macular degeneration (AMD) is the leading cause of blindness in the western world. Intravitreal injection of anti-vascular endothelial gro...

Oct 31 2019 31671463
Antioxidant, Anti-Melanogenic and Anti-Wrinkle Effects of .

In this study, the antioxidant, anti-xanthine oxidase, anti-melanogenic and anti-wrinkle effects of methanol (ME) and hot water (HE) extracts from the...

Oct 15 2019 32010471
Sepsis in Latent Autoimmune Diabetes in Adults with Diabetic Ketoacidosis: A Case Report.

BACKGROUND: This case report intends to highlight the challenge in diagnosing type 1 diabetes on an adult patient. Latent Autoimmune Diabetes in Adult...

Oct 14 2019 32002083
The complement system in liver diseases: Evidence-based approach and therapeutic options.

Complement is usually seen to largely originate from the liver to accomplish its tasks systemically - its return to the production site has long been ...

Sep 18 2019 32743505
Uncovering convolutional neural network decisions for diagnosing multiple sclerosis on conventional MRI using layer-wise relevance propagation.

Machine learning-based imaging diagnostics has recently reached or even surpassed the level of clinical experts in several clinical domains. However, ...

Sep 6 2019 31634822
Novel small molecule retrograde transport blocker confers post-exposure protection against ricin intoxication.

Ricin is a highly toxic type 2 ribosome-inactivating protein (RIP) which is extracted from the seeds of castor beans. Ricin is considered a potential ...

Aug 22 2019 32140395
Strategies to Tackle the Global Burden of Diabetic Retinopathy: From Epidemiology to Artificial Intelligence.

Diabetes is a global public health disease projected to affect 642 million adults by 2040, with about 75% residing in low- and middle-income countries...

Aug 13 2019 31408872
Machine learning defined diagnostic criteria for differentiating pituitary metastasis from autoimmune hypophysitis in patients undergoing immune checkpoint blockade therapy.

PURPOSE: New-onset pituitary gland lesions are observed in up to 18% of cancer patients undergoing treatment with immune checkpoint blockers (ICB). We...

Aug 12 2019 31415986
Machine learning approaches to predict lupus disease activity from gene expression data.

The integration of gene expression data to predict systemic lupus erythematosus (SLE) disease activity is a significant challenge because of the high ...

Jul 3 2019 31270349
HyperFoods: Machine intelligent mapping of cancer-beating molecules in foods.

Recent data indicate that up-to 30-40% of cancers can be prevented by dietary and lifestyle measures alone. Herein, we introduce a unique network-base...

Jul 3 2019 31270435
GAIL: An interactive webserver for inference and dynamic visualization of gene-gene associations based on gene ontology guided mining of biomedical literature.

In systems biology, inference of functional associations among genes is compelling because the construction of functional association networks facilit...

Jul 1 2019 31260503
A case of robotic assisted percutaneous coronary intervention of the left main coronary artery in a patient with very late baffle stenosis after surgical correction of anomalous left coronary artery from the pulmonary artery.

A 34-year-old woman with history of surgical correction (Takeuchi procedure) of anomalous left coronary artery from the pulmonary artery (ALCAPA) pres...

Jun 27 2019 31250510
A new M23-based ELISA assay for anti-aquaporin 4 autoantibodies: diagnostic accuracy and clinical correlation.

PURPOSE: Although many assays have been developed to detect anti-aquaporin-4 (AQP4) antibodies, most of these assays require sophisticated techniques ...

Jun 19 2019 32257061
Modelling disease risk for amyloid A (AA) amyloidosis in non-human primates using machine learning.

Amyloid A (AA) amyloidosis is found in humans and non-human primates, but quantifying disease risk prior to clinical symptoms is challenging. We appl...

Jun 18 2019 31210531
Detecting mitotic cells in HEp-2 images as anomalies via one class classifier.

We propose a novel framework for classification of mitotic v/s non-mitotic cells in a Computer Aided Diagnosis (CAD) system for Anti-Nuclear Antibodie...

Jun 17 2019 31326866
Quantitative Structure-Activity Relationships for Structurally Diverse Chemotypes Having Anti- Activity.

Small-molecule compounds that have promising activity against macromolecular targets from occasionally fail when tested in whole-cell phenotypic assa...

Jun 8 2019 31181717
Pre-Treatment Biomarkers of Anti-Tumour Necrosis Factor Therapy Response in Crohn's Disease-A Systematic Review and Gene Ontology Analysis.

The most prominent treatment for the serious cases of Crohn's disease (CD) are biological tumour necrosis factor (TNF) inhibitors. Unfortunately, ther...

May 28 2019 31141991
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