Latest AI and machine learning research in rheumatology for healthcare professionals.
Whole-genome sequencing comprehensively captures coding, non-coding and structural variation in families with suspected inherited disorders, yet its clinical utility remains constrained by an interpretation bottleneck: selecting a handful of relevant variants from millions of candidates. Current rule-based pipelines, anchored in ACMG/AMP criteria, excel at identifying highly penetrant Mendelian al...
Document image binarization aims to separate foreground text from degraded backgrounds while preserving thin, broken, and low-contrast strokes. Although deep learning methods have improved binarization performance, most existing approaches rely on convolutional, transformer-based, or generative architectures, while Mamba-based state space models remain largely unexplored for this task. In this wor...
Liver sinusoidal endothelial cells (LSECs) are increasingly recognized as a critical yet underexplored cell type in anti-fibrotic drug development. Th...
In view of the outstanding progress of machine learning (ML) and growing cost of health systems, it is a current challenge to incorporate artificial i...
Background and Objectives Patients with peripheral neuropathies (PN) commonly exhibit balance impairment. In clinical practice, balance is typically a...
1. Classifying animal movement strategies from GPS tracking data is essential for understanding space use, population dynamics and conservation planni...
Drug repurposing offers a cost-effective strategy to accelerate therapeutic discovery, but most computational approaches fail to model noncoding genet...
Translating transcriptomic data into therapeutic hypotheses remains fragmented and labor-intensive. Here we present ConvergeCELL, a platform combining...
Rheumatoid arthritis (RA) assessment from hand radiographs requires multi-level analysis and modeling of anatomical structures and fine-grained local ...
We present EDDY (Exact-marginal Diversification via Divergence-free dYnamics), a guidance mechanism for diffusion and flow matching models that promot...
Kawasaki disease (KD) is a systemic vasculitis in young children, and early diagnosis remains challenging when clinical features are incomplete or ove...
Objectives This study aimed to develop and validate machine learning models to predict in-hospital mortality among systemic lupus erythematosus (SLE) ...
The rapid growth of molecular foundation models and general-purpose large language models has encouraged a scale-centric view of artificial intelligen...
Disease progression varies with age and is influenced by underlying genetic, biochemical, and hormonal etiologies, suggesting the need for tailored mo...
Metabolic dysfunction is increasingly recognized as a risk factor for poor outcomes in breast cancer, but whether incretin-based therapies confer surv...
Multimodal learning has the potential to improve clinical prediction by integrating complementary data sources, but the incremental value of imaging b...
Anti-doping programs rely on biological testing to detect performance-enhancing drugs, but such testing costs over $800 per sample and is limited by s...
The rapid progress of subject-driven text-to-image synthesis, and in particular DreamBooth, has enabled a consent-free deepfake pipeline: an adversary...
The capacity to generate high-dimensional biological datasets has outpaced the ability to interpret them. Technologies such as phage immunoprecipitati...
Adaptive medical AI models often face performance drops in dynamic clinical environments due to data drift. We propose an autonomous continuous monito...