Rheumatology

Cocaine-induced vasculitis with cutaneous manifestation: A recurrent episode after 2 years.

Cocaine is a popular recreational drug in the United States, and up to 70% of the seized cocaine contains levamisole which is an antihelminthic that can cause cutaneous vasculitis with necrosis and positive antineutrophil cytoplasmic antibodies (ANCAs). Here, we report a unique case of recurrent cocaine-induced vasculitis in a patient who smokes cocaine for more than 20 years. A 38-year-old woman ...

Alantolactone exhibited anti-herpes simplex virus 1 (HSV-1) action in vitro.

The aim of this study was to determine the inhibitory action of alantolactone, a gradient of traditional Chinese medicine Inulae Radix (Tu-Mu-Xiang), on herpes simplex virus 1 (HSV-1). African green monkey kidney cells (Vero cells) were infected with HSV-1 and the protective effects of alantolactone on Vero cells were examined. At concentrations of 10(-6), 10(-7), and 10(-8) g/mL, alantolactone di...

Factor V Leiden and Cardiopulmonary Bypass.

We present a case of a patient with factor V Leiden with an antithrombin III activity of 67% who received a successful aortic valve replacement suppor...

Antioxidant Activity and Anti-wrinkle Effects of Aceriphyllum rossii Leaf Ethanol Extract.

We evaluated the antioxidant activity and anti-wrinkle effects of Aceriphyllum rossii leaf ethanol extract (ARLEE) in vitro using human dermal fibrobl...

Honey Bee Venom (Apis mellifera) Contains Anticoagulation Factors and Increases the Blood-clotting Time.

OBJECTIVES: Bee venom (BV) is a complex mixture of proteins and contains proteins such as phospholipase and melittin, which have an effect on blood cl...

[Anti-aging Effect of Urtica Polysaccharides in D-galactose Induced Aging Mice].

OBJECTIVE: To investigate the anti-aging effect of polysaccharides from Urtica lobatifolia (Urtica polysaccharides) on subacute aging mice induced by ...

[A Case of Bullous Pemphigoid Relieved after Sigmoid Colon Cancer Resection].

A 76-year-old man presented with many bullous lesions and erythema over his whole body in August 2014. Blood examination showed an elevation of the an...

[Experimental study on effect of model on hepatic fibrosis with Aralia chinesis].

Hepatic fibrosis models were induced by CCl4 in rats. To explore vascular endothelial growth factor (VEGF), transforming growth factor-beta1 (TGFβ1) m...

[Observation of curative effect of hemorrhoids lotion on pain, edema and bleeding after anorectal surgery].

The purpose of this study was to evaluate the value of Chinese herbal fumigation in the postoperative anal disease. The authors randomly divided 348 p...

Robotic printing and drug testing of 384-well tumor spheroids.

A major impediment to anti-cancer drug development is the lack of a reliable and inexpensive tumor model to test the efficacy of candidate compounds. ...

Support vector machines using EEG features of cross-frequency coupling can predict treatment outcome in Mecp2-deficient mice.

Anti-convulsive drug treatments of epilepsy typically produce varied outcomes from one patient to the next, often necessitating patients to go through...

Measuring physician adherence with gout quality indicators: a role for natural language processing.

OBJECTIVE: To evaluate physician adherence with gout quality indicators (QIs) for medication use and monitoring, and behavioral modification (BM).

Role of moving average analysis for development of multi-target (Q)SAR models.

In modern drug discovery era, multi target- quantitative structure activity relationship [mt- (Q)SAR] approaches have emerged as novel and powerful al...

Applying machine learning to gait analysis data for disease identification.

A machine-learning framework to identify the specific disease afflicting certain patients diagnosed with Neurological and Neuromuscular Diseases (NND)...

A Study of Applications of Machine Learning Based Classification Methods for Virtual Screening of Lead Molecules.

The ligand-based virtual screening of combinatorial libraries employs a number of statistical modeling and machine learning methods. A comprehensive a...

Comparison between the therapeutic effects of robotic-assisted locomotor training and an anti-spastic medication on spasticity.

We studied the effects of robotic-assisted locomotor (LOKOMAT) training or an anti-spastic medication (tizanidine) on neuromuscular abnormality associ...

[A case report of hepatitis B virus reactivation in a hepatitis B core antibody-positive, hepatitis B surface antigen-negative hemodialysis patient].

Reactivation of the hepatitis B virus (HBV) has been reported in patients receiving immunosuppressive therapy or chemotherapy. We report a case of HBV...