Rheumatology

Latest AI and machine learning research in rheumatology for healthcare professionals.

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Harnessing of real-world data and real-world evidence using digital tools: utility and potential models in rheumatology practice.

The diversity of diseases in rheumatology and variability in disease prevalence necessitates greater data parity in disease presentation, treatment responses including adverse events to drugs and various comorbidities. Randomized controlled trials are the gold standard for drug development and performance evaluation. However, when the drug is applied outside the controlled environment, the outcome...

Feb 2 2022 34528081

circRNA-binding protein site prediction based on multi-view deep learning, subspace learning and multi-view classifier.

Circular RNAs (circRNAs) generally bind to RNA-binding proteins (RBPs) to play an important role in the regulation of autoimmune diseases. Thus, it is crucial to study the binding sites of RBPs on circRNAs. Although many methods, including traditional machine learning and deep learning, have been developed to predict the interactions between RNAs and RBPs, and most of them are focused on linear RN...

Jan 17 2022 34571539
Computational anti-COVID-19 drug design: progress and challenges.

Vaccines have made gratifying progress in preventing the 2019 coronavirus disease (COVID-19) pandemic. However, the emergence of variants, especially ...

Jan 17 2022 34850817
Heavy chain sequence-based classifier for the specificity of human antibodies.

Antibodies specifically bind to antigens and are an essential part of the immune system. Hence, antibodies are powerful tools in research and diagnost...

Jan 17 2022 34953464
Towards gender equity in artificial intelligence and machine learning applications in dermatology.

There has been increased excitement around the use of machine learning (ML) and artificial intelligence (AI) in dermatology for the diagnosis of skin ...

Jan 12 2022 34151976
Artificial intelligence and machine learning methods in predicting anti-cancer drug combination effects.

Drug combinations have exhibited promising therapeutic effects in treating cancer patients with less toxicity and adverse side effects. However, it is...

Nov 5 2021 34347041
Large-scale comparative review and assessment of computational methods for anti-cancer peptide identification.

Anti-cancer peptides (ACPs) are known as potential therapeutics for cancer. Due to their unique ability to target cancer cells without affecting healt...

Jul 20 2021 33316035
Unveiling the immune infiltrate modulation in cancer and response to immunotherapy by MIXTURE-an enhanced deconvolution method.

The accurate quantification of tumor-infiltrating immune cells turns crucial to uncover their role in tumor immune escape, to determine patient progno...

Jul 20 2021 33320931
A convolutional neural network algorithm for breast tumor detection with magnetic detection electrical impedance tomography.

Breast cancer is a malignant tumor disease for which early detection, diagnosis, and treatment are of paramount significance in prolonging the life of...

Jun 1 2021 34243519
Dr AFC: drug repositioning through anti-fibrosis characteristic.

Fibrosis is a key component in the pathogenic mechanism of a variety of diseases. These diseases involving fibrosis may share common mechanisms and th...

May 20 2021 32572450
Predictive modeling based on small data in clinical medicine: RBF-based additive input-doubling method.

The paper considers the problem of handling short sets of medical data. Effectively solving this problem will provide the ability to solve numerous cl...

Mar 17 2021 33892562
Classifying Pseudogout Using Machine Learning Approaches With Electronic Health Record Data.

OBJECTIVE: Identifying pseudogout in large data sets is difficult due to its episodic nature and a lack of billing codes specific to this acute subtyp...

Mar 1 2021 31910317
Machine Learning in Rheumatic Diseases.

With advances in information technology, the demand for using data science to enhance healthcare and disease management is rapidly increasing. Among t...

Feb 1 2021 32681407
The Dark Kinase Knowledgebase: an online compendium of knowledge and experimental results of understudied kinases.

Kinases form the backbone of numerous cell signaling pathways, with their dysfunction similarly implicated in multiple pathologies. Further facilitate...

Jan 8 2021 33079988
Unexpected Inequality: Disparate-Impact From Artificial Intelligence in Healthcare Decisions.

Systemic discrimination in healthcare plagues marginalized groups. Physicians incorrectly view people of color as having high pain tolerance, leading ...

Jan 1 2021 34185974
Chronic kidney disease in Hepatitis C and its association with liver cirrhosis and viral load: Revealing the importance of hematuria.

Hepatitis C virus (HCV) contributed as a risk factor for chronic kidney disease (CKD). Many studies only showed it associated with estimated glomerula...

Jan 1 2021 35532700
SERUM ZONULIN LEVELS IN HYPOTHYROID AND EUTHYROID PATIENTS WITH HASHIMOTO'S THYROIDITIS - A PILOT STUDY.

CONTEXT: Human zonulin is a protein that regulates the intercellular tight junctions in various tissues and organs of the human body. Hashimoto's thyr...

Jan 1 2021 35747862
[High-efficiency separation and analysis of monosaccharides in Pueraria polysaccharides by pressurized capillary electrochromatography].

Pueraria polysaccharides have been proven to possess biological activities such as bacteriostasis, anti-oxidative, anti-tumor, and immunity boosting a...

Nov 8 2020 34213104
Optical coherence tomography-based diabetic macula edema screening with artificial intelligence.

BACKGROUND: Optical coherence tomography (OCT) is considered as a sensitive and noninvasive tool to evaluate the macular lesions. In patients with dia...

Nov 1 2020 32452907
Towards development of a novel universal medical diagnostic method: Raman spectroscopy and machine learning.

Many problems exist within the myriad of currently employed screening and diagnostic methods. Further, an incredibly wide variety of procedures are us...

Oct 19 2020 32996518
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