Neurology

Seizures

Latest AI and machine learning research in seizures for healthcare professionals.

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Predicting Antiseizure Medication Outcomes in Early Diagnosed Epilepsy: A Multimodal Framework Using EEG, MRI, and Clinical Data

Accurate prediction of antiseizure medication (ASM) outcomes is crucial for optimising epilepsy treatment. We propose a multi-modal deep learning framework that integrates electroencephalography (EEG), magnetic resonance imaging (MRI), clinical factors, and molecular drug features to enhance ASM outcome prediction. Our approach includes EEG Q-Net, a pre-trained quantisation model capturing finegra...

Automated Detection of Faciobrachial Dystonic Seizures Related Events in LGI1 Autoimmune Encephalitis Patients with Wearables

To evaluate the potential of wrist-worn wearable devices to detect and quantify Faciobrachial Dystonic Seizures (FBDS) and related events associated with leucine-rich glioma Inactivated-1 (LGI1)-IgG autoimmune encephalitis (LGI1 AIE). Seven patients and four control subjects were monitored with Empatica E4 wristbands in both hospital and ambulatory environments. The analysis focused on the pre- an...

FFT Power Relationships Applied to EEG Signal Analysis: A Meeting between Visual Analysis of EEG and Its Quantification

This study presents a novel computational approach for analyzing electroencephalogram (EEG) signals, focusing on the distribution and variability of e...

Pose AI prediction of neurological status in the Neuroscience Intensive Care Unit

The neurological exam is pivotal in assessing patients with neurological conditions but has severe limitations: it can vary between examiners, it may ...

OpenSpindleNet: An Open-Source Deep Learning Network for Reliable Sleep Spindle Detection

Sleep spindles, an oscillatory brain activity occurring during light non-rapid eye movement (NREM) sleep, are important for memory consolidation and c...

Continuous Reaching and Grasping with a BCI Controlled Robotic Arm in Healthy and Stroke-Affected Individuals

Recent advancements in signal processing techniques have enabled non-invasive Brain-Computer Interfaces (BCIs) to control assistive devices, like robo...

Independent Evaluation of Deep Learning Models for Detecting Focal Cortical Dysplasia

The objective of this study is to perform an independent assessment of the diagnostic utility of three state-of-the-art tools for the detection of foc...

The impact of EEG preprocessing parameters on ultra-low-power seizure detection

Closed-loop neurostimulation is a promising treatment for drug-resistant focal epilepsy. A major challenge is fast and reliable seizure detection via ...

PyHFO 2.0: An Open-Source Platform for Deep Learning–Based Clinical High-Frequency Oscillations Analysis

Accurate detection and classification of high-frequency oscillations (HFOs) in electroencephalography (EEG) recordings have become increasingly import...

Machine Learning-Enabled EEG Biomarkers Predict Divergent Antidepressant and Placebo Response in a Clinical Trial of Major Depression

Major depressive disorder (MDD) is a heterogeneous neuropsychiatric disorder with highly variable antidepressant outcomes. In randomized controlled tr...

Automated detection of bottom-of-sulcus dysplasia on MRI-PET in patients with drug-resistant focal epilepsy

Bottom-of-sulcus dysplasia (BOSD) is a diagnostically challenging subtype of focal cortical dysplasia, 60% being missed on patients’ first MRI. Automa...

A Single-Channel EEG Approach for Sleep Stage-Independent Automatic Detection of REM Sleep Behavior Disorder

Rapid Eye Movement (REM) Sleep Behavior Disorder (RBD) is a parasomnia characterized by the loss of physiological muscle atonia during REM sleep, ofte...

Artificial Intelligence enhanced R1 maps can improve lesion detection in focal epilepsy in children

MRI is critical for the detection of subtle cortical pathology in epilepsy surgery assessment. This can be aided by improved MRI quality and resolutio...

Interictal Epileptiform Discharge Detection Using Probabilistic Diffusion Models and AUPRC Maximization

Recently, automated Interictal Epileptiform Discharge (IED) detection has attracted significant attention as a challenging predictive data analysis ta...

ROC Analysis of Biomarker Combinations in Fragile X Syndrome-Specific Clinical Trials: Evaluating Treatment Efficacy via Exploratory Biomarkers

Fragile X Syndrome (FXS) is a rare neurodevelopmental disorder caused by a trinucleotide repeat expansion on the 5’ untranslated region of the FMR1 ge...

Electroencephalographic features of chronic subjective tinnitus: A scoping review

The goal of this scoping review is to review the scope of features from previous resting-state electroencephalography (EEG) research that have the pot...

Clinically reported covert cerebrovascular disease and risk of neurological disease: a whole-population cohort of 395,273 people using natural language processing

Understanding the relevance of covert cerebrovascular disease (CCD) for later health will allow clinicians to more effectively monitor and target inte...

Development of Machine Learning Algorithms Using EEG Data to Detect the Presence of Chronic Pain

Chronic pain impacts more than one in five adults in the United States (US) and the costs associated with the condition amount to hundreds of billions...

AI-Driven Personalization of Dual Antiplatelet Therapy Duration Post-PCI: A Novel Approach Balancing Ischemic and Bleeding Risks

Precision-guided dual antiplatelet therapy (DAPT) duration post-percutaneous coronary intervention (PCI) remains a clinical challenge. Current risk st...

Event-based seizure detection in human iEEG with neuromorphic hardware

Epilepsy is a neurological disorder that affects approximately 1% of the global population. The current method for seizure monitoring, seizure diaries...

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