Neurology

Seizures

Latest AI and machine learning research in seizures for healthcare professionals.

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Deep learning based treatment remission prediction to transcranial direct current stimulation in bipolar depression using EEG power spectral density

Bipolar disorder is characterized by marked changes in mood and activity levels and is a leading cause of disability worldwide. We sought to investigate the application of deep learning methods to electroencephalogram (EEG) signals to predict clinical remission after 6 weeks of home-based transcranial direct current stimulation (tDCS) treatment. Pre-treatment resting-state EEG acquired from 21 bip...

Effects of Parietal Cathodal tDCS during Game Cue Exposure on Internet Gaming Disorder: A Randomized Double-Blind Sham-Controlled Trial

Internet Gaming Disorder (IGD) is officially listed as a behavioral addiction, exhibits high prevalence and has inadequate treatment efficacy. Targeting craving triggered by gaming cues represents a critical therapeutic objective. This study aimed to establish optimizing neuro-electrophysiologic biomarkers for IGD and develop a targeted neuromodulation protocol. In an exploratory study, we identif...

Transformer Models Enable Accurate Age Prediction From Sleep Physiology

Biological age estimation, derived from physiological signatures such as brain activity, is emerging as a valuable biomarker for health and well-being...

Development and Validation of a Deep Survival Model to Predict Time-to-Seizure from Routine EEG

To develop and validate a deep survival model (EEGSurvNet) that analyzes routine EEG to predict individual seizure risk over time, comparing its perfo...

Adapting Biomedical Foundation Models for Predicting Outcomes of Anti Seizure Medications

Epilepsy affects over 50 million people worldwide, with anti-seizure medications (ASMs) as the primary treatment for seizure control. However, ASM sel...

Personalized, closed-loop deep brain stimulation for chronic pain

Chronic pain is a major healthcare problem associated with maladaptive brain circuit changes - many patients are unresponsive to all available therapi...

Bridging Computational and Clinical Strategies to Improve Presurgical Identification of Epileptogenic Networks

About one third of epilepsy patients are drug-resistant. Resective surgery remains a key treatment option but depends critically on accurate identific...

Machine Learning-Based Reconstruction of 2D MRI for Quantitative Morphometry in Epilepsy

Structural neuroimaging analyses require ‘research quality’ images, acquired with costly MRI acquisitions. Isotropic (3D-T1) images are desirable for ...

Evaluating the Generalizability of EEG-Based AI Models in Alzheimer’s and Dementia Diagnosis

We thoroughly investigated the generalizability of deep learning models trained on electroencephalography (EEG) data to detect Alzheimer’s disease and...

Interpretable Transformer Models for rs-fMRI Epilepsy Classification and Biomarker Discovery

Automated interpretation of resting-state fMRI (rs-fMRI) for epilepsy diagnosis remains a challenge. We developed a regularized transformer that model...

Neuromorphic Neuromodulation: A Low-Power Edge-Training Framework for the Future of Personalized and Closed-Loop Neurostimulation

Epilepsy affects approximately 1% of the global population, with 30-40% of cases resistant to conventional pharmacological treatments. Current neurost...

Objective Assessment of Microperimetry Exam Using EEG Signals

To test the hypothesis that deep learning can decode single-trial cortical responses from electroencephalography (EEG) to individual, long-duration mi...

Plasma proteomics of seizure-associated changes in epilepsy

Fluid biomarkers are emerging as crucial markers for diagnosis and disease monitoring in neurology. Epilepsy remains an exception despite seizures bei...

Dementia Risk and Machine Learning-Derived Brain Age Index from Sleep Electroencephalography: A Pooled Cohort Analysis of Over 7,000 Individuals Across Five Community Cohorts

Sleep electroencephalographic (EEG) microstructures are closely related to cognition and undergo age-dependent changes. However, their multidimensiona...

Classifying Obsessive-Compulsive Disorder from Resting-State EEG using Convolutional Neural Networks: A Pilot Study

Objective: Identifying obsessive-compulsive disorder (OCD) using brain data remains challenging. Resting-state electroencephalography (EEG) offers an ...

Synthesising Interictal Epileptiform Discharges With Generative Adversarial Network

Interictal epileptiform discharges (IEDs) are reliable biomarkers in electroencephalograms for epilepsy. To automate IED detection, deep learning (DL)...

A Deep Lightweight Convolutional Neural Network for Detecting Artifacts in Continuous EEG Signals

This study aimed to develop and validate a system of specialized deep lightweight convolutional neural networks (CNN) to accurately detect specific ar...

Real-Time EEG-Based Epileptic Seizure Prediction Using Artificial Intelligence: A Systematic Review

Epilepsy affects approximately 50 million people worldwide, and seizures remain difficult to predict in onset, severity, and duration. Real-time seizu...

Epileptic Seizure Detection based on Different Events with XAI and Early Aid System for Patient Aid

The goal of this study is seizure detection in four class datasets for different seizure stages in epileptic patients. An early notification system is...

Automated Seizure Classification Using Multimodal Large Language Models

Accurately distinguishing between epileptic seizures (ES) and nonepileptic seizures (NES) is a significant clinical challenge that typically requires ...

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