Sepsis

Robot-assisted stereotactic multiple brain abscesses' puncture: technical case report.

We report a case of multiple brain abscesses' puncture, employing the ROSA™ Brain surgical robot (Zimmer Biomet) and the O-arm® O2 Imaging System (Medtronic). A 51-year-old man was diagnosed with multiple supratentorial ring enhancing cystic lesions consistent with brain abscesses. A neurological deterioration occurred despite broad spectrum antibiotic therapy, due to mass effect of the abscesses....

An approach to rapidly assess sepsis through multi-biomarker host response using machine learning algorithm.

Sepsis is a life-threatening condition and understanding the disease pathophysiology through the use of host immune response biomarkers is critical for patient stratification. Lack of accurate sepsis endotyping impedes clinicians from making timely decisions alongside insufficiencies in appropriate sepsis management. This work aims to demonstrate the potential feasibility of a data-driven validati...

Classification for avian malaria parasite Plasmodium gallinaceum blood stages by using deep convolutional neural networks.

The infection of an avian malaria parasite (Plasmodium gallinaceum) in domestic chickens presents a major threat to the poultry industry because it ca...

Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy.

For an emerging disease like COVID-19, systems immunology tools may quickly identify and quantitatively characterize cells associated with disease pro...

RCoNet: Deformable Mutual Information Maximization and High-Order Uncertainty-Aware Learning for Robust COVID-19 Detection.

The novel 2019 Coronavirus (COVID-19) infection has spread worldwide and is currently a major healthcare challenge around the world. Chest computed to...

Editorial: The National COVID Cohort Collaborative Consortium Combines Population Data with Machine Learning to Evaluate and Predict Risk Factors for the Severity of COVID-19.

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) commonly presents with pne...

Co-AMPpred for in silico-aided predictions of antimicrobial peptides by integrating composition-based features.

BACKGROUND: Antimicrobial peptides (AMPs) are oligopeptides that act as crucial components of innate immunity, naturally occur in all multicellular or...

Early detection of COVID-19 in the UK using self-reported symptoms: a large-scale, prospective, epidemiological surveillance study.

BACKGROUND: Self-reported symptoms during the COVID-19 pandemic have been used to train artificial intelligence models to identify possible infection ...

Country transition index based on hierarchical clustering to predict next COVID-19 waves.

COVID-19 has widely spread around the world, impacting the health systems of several countries in addition to the collateral damage that societies wil...

COVID-19 Automatic Diagnosis With Radiographic Imaging: Explainable Attention Transfer Deep Neural Networks.

Researchers seek help from deep learning methods to alleviate the enormous burden of reading radiological images by clinicians during the COVID-19 pan...

MSDS-UNet: A multi-scale deeply supervised 3D U-Net for automatic segmentation of lung tumor in CT.

Lung cancer is one of the most common and deadly malignant cancers. Accurate lung tumor segmentation from CT is therefore very important for correct d...

A model of modified -iodobenzylguanidine conjugated gold nanoparticles for neuroblastoma treatment.

Iodine-131 -iodobenzylguanidine (I-IBG) has been utilized as a standard treatment to minimize adverse side effects by targeting therapies to bind to t...

Combination Therapy of Chloramphenicol and Daptomycin for the Treatment of Infective Endocarditis Secondary to Multidrug Resistant .

A 38-years-old female with an aortic valve replacement presented to an outside hospital (OSH) with fevers and malaise. Blood cultures revealed VRE whi...

Machine learning application for the prediction of SARS-CoV-2 infection using blood tests and chest radiograph.

Triaging and prioritising patients for RT-PCR test had been essential in the management of COVID-19 in resource-scarce countries. In this study, we ap...

Dual-Organ Transcriptomic Analysis of Rainbow Trout Infected With Through Co-Expression and Machine Learning.

is a major pathogen that causes a high mortality rate in trout farms. However, systemic responses to the pathogen and its interactions with multiple ...

Evaluating the Efficacy of Povidone-Iodine Solution Infection Prophylaxis in Immediate Tissue Expander-Based Breast Reconstruction: A Controlled Retrospective Analysis.

There is currently no consensus among plastic surgeons regarding the optimal infection prophylaxis for immediate tissue expander placement following ...

Timesias: A machine learning pipeline for predicting outcomes from time-series clinical records.

The prediction of outcomes is a critical part of the clinical surveillance for hospitalized patients. Here, we present Timesias, a machine learning pi...

On the Role of Arkypallidal and Prototypical Neurons for Phase Transitions in the External Pallidum.

The external pallidum (globus pallidus pars externa [GPe]) plays a central role for basal ganglia functions and dynamics and, consequently, has been i...

Polydopamine coated hypodermic needles as a microextraction device for the determination of tricyclic antidepressants in oral fluid by direct infusion MS/MS.

In-needle microextraction consists of the confinement of the sorbent, by coating or packing, inside a metallic needle. The size of the needles reduces...

Face mask detection using deep learning: An approach to reduce risk of Coronavirus spread.

Effective strategies to restrain COVID-19 pandemic need high attention to mitigate negatively impacted communal health and global economy, with the br...