Stem Cell Research

From lab to life: technological innovations in transforming cancer metastasis detection and therapy.

Prediction of Early Recurrence After Bronchial Arterial Chemoembolization in Non-small Cell Lung Cancer Patients Using Dual-energy CT: An Interpretable Model Based on SHAP Methodology.

RATIONALE AND OBJECTIVES: Bronchial artery chemoembolization (BACE) is a new treatment method for lu...

Pharmacovigilance in Cell and Gene Therapy: Evolving Challenges in Risk Management and Long-Term Follow-Up.

Cell and gene therapies, including CAR T-cells, CRISPR-based genome editing, and next-generation vir...

Ligand supplementation restores the cancer therapy efficacy of the antirheumatic drug auranofin from serum inactivation.

Auranofin, an FDA-approved antirheumatic gold drug, has gained ongoing interest in clinical studies ...

Nursing leadership and artificial intelligence ethics: Safeguarding relationships and values.

The integration of artificial intelligence (AI) into healthcare marks a paradigmatic shift, raising ...

Application of causal forest double machine learning (DML) approach to assess tuberculosis preventive therapy's impact on ART adherence.

Adherence to antiretroviral therapy (ART) is critical for HIV treatment success, yet the impact of t...

Real-time prediction of intensive care unit patient acuity and therapy requirements using state-space modelling.

Intensive care unit (ICU) patients often experience rapid changes in clinical status, requiring time...

Ethical Challenges to the Adoption of AI in Healthcare: A Review.

There are few comprehensive summaries of the ethical challenges associated with the adoption of arti...

The role of electrical stimulation in bone regeneration: mechanistic insights and therapeutic advances.

Bone regeneration is a complex biological process that involves the coordinated action of osteoblast...

The Practical, Robust Implementation and Sustainability (PRISM)-capabilities model for use of Artificial Intelligence in community-engaged implementation science research.

BACKGROUND: Community-engaged research (CER) leverages knowledge, insights, and expertise of researc...

Strengthening Africa's brain health and economic resilience.

Africa stands at a decisive moment in which urgent action is essential to safeguard its brain health...

Machine learning on multiple epigenetic features reveals H3K27Ac as a driver of gene expression prediction across patients with glioblastoma.

Epigenetic mechanisms play a crucial role in driving transcript expression and shaping the phenotypi...

Next-generation smart wound dressings: AI integration, biosensors, and electrospun nanofibers for chronic wound therapy.

Polymeric biomaterials, particularly electrospun nanofibers, are increasingly central to the develop...

Analysis of Factors Influencing Immunological Failure in Elderly People Living with HIV Undergoing Antiretroviral Therapy: A LASSO-Logistic Regression Approach.

This study aimed to identify key predictors of immunological failure in elderly patients with HIV re...

Dynamic neural network modulation associated with rumination in major depressive disorder: a prospective observational comparative analysis of cognitive behavioral therapy and pharmacotherapy.

Cognitive behavioral therapy (CBT) and pharmacotherapy are primary treatments for major depressive d...

Short and long-term impact of intravitreal anti-VEGF therapy interruption in retinal vein occlusion during the COVID-19 pandemic: functional outcomes and AI-based fluid analysis of macular edema.

BACKGROUND: The aim of the study is to investigate the short- and long-term effects of delayed intra...

Developing a code of ethics in health information management.

An effective strategy for promoting ethics within organisations is to establish clear guidelines th...

Chat-IRB? How application-specific language models can enhance research ethics review.

Institutional review boards (IRBs) play a crucial role in ensuring the ethical conduct of human subj...

Artificial intelligence in hematopoietic stem cell transplantation care and complication management.

The practice of allogeneic hematopoietic stem cell transplantation (alloHCT) has evolved from an exp...

A Sensor Array Composed of Organelle-Targeting Fluorescent Probes and Polydopamine Particles for Deep Learning-Assisted Identification and Ablation of Drug-Resistant Lung Tumors.

Lung cancer, a leading cause of global cancer-related mortality, predominantly features nonsmall cel...

Harnessing the Potential of Carotenoids for Cancer Therapy: An Integrated Machine Learning and MST Based Approach.

Receptor tyrosine kinases (RTKs) are high-affinity membrane-anchored receptors involved in cellular ...