Latest AI and machine learning research in stem cell research for healthcare professionals.
BACKGROUND: All patients with rifampicin-resistant tuberculosis should receive a short course of effective treatment. We aimed to evaluate the effectiveness of whole genome sequencing (WGS)-guided treatment in shortening duration of treatment for rifampicin-resistant tuberculosis. METHODS: We did a pragmatic, randomised, single-blind phase 4 trial in 13 hospitals and 35 clinics in South Africa. Ad...
In vivo chimeric antigen receptor (CAR) cell therapy is undergoing a transformative shift from conventional ex vivo manufacturing toward in situ cellular editing, aiming to generate functional CAR-engineered immune cells directly within patients through targeted vector delivery, thereby significantly enhancing therapeutic accessibility and applicability. While rapid advances have been made in both...
Immunotherapy has revolutionized hepatocellular carcinoma (HCC) management, necessitating personalized strategies in current guidelines. Despite curat...
Precision-guided therapy is imperative in the battle against pancreatic ductal adenocarcinoma (PDAC), one of the most lethal solid malignancies with l...
BACKGROUND: Accurate prediction of pathological complete response (pCR) after preoperative chemoradiation therapy, followed by surgery (trimodality th...
The integration of measurable residual disease (MRD) into the management of chronic lymphocytic leukemia (CLL) has emerged as a major advance in risk ...
Mesoporous graphene frameworks (MGFs) were synthesized as p-type semiconductors with a nonzero band gap of ~1 eV and used as 3D photo-sensitive scaffo...
Cranio-maxillofacial bone defects resulting from trauma, tumors, infection, or congenital malformations not only severely impair patients' physiologic...
Bone organoids have emerged as transformative models for studying bone development and disease by recapitulating complex cellular ecosystems in vitro....
The rapid escalation of antimicrobial resistance (AMR) represents a major global health challenge, undermining the clinical efficacy of conventional a...
Malachite green (MG), a synthetic dye, has turned into a major risk to human health, because of its toxicity of teratogenic, genotoxic, carcinogenic, ...
BACKGROUND: Ambient artificial intelligence (AI) scribes can reduce the burden of administrative documentation. Prior evaluations have been vendor spe...
INTRODUCTION: Industry funding for research is important in the era of decreasing federal research support. The goal of this study was to assess the t...
BACKGROUND: Continuous Positive Airway Pressure (CPAP) therapy is the standard treatment for obstructive sleep apnea-hypopnea syndrome, yet its use as...
INTRODUCTION: Liver tumours are a leading cause of global morbidity and mortality. Current diagnostic tools, including computed tomography (CT), magne...
Osteosarcoma is the most common malignant bone tumor in children and adolescents, usually affecting the long bones of the limbs. Despite progress in s...
Repetitive transcranial magnetic stimulation (rTMS) to the primary motor cortex (M1) provides significant pain relief in ∼45% of chronic pain patients...
Humanity is entering a new phase of social evolution with rapid digitalisation and increasing use of artificial intelligence in our lives. Psychiatric...
Cell therapies have demonstrated great potential for treating a broad range of diseases where conventional treatments have failed. However, long devel...
The rapid integration of artificial intelligence (AI) into research presents emerging ethical and governance challenges for institutions overseeing hu...