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Showing 1891-1911 of 5,037 articles

Assessment of Functional Phosphatidylinositol 3-Kinase Pathway Activity in Cancer Tissue Using Forkhead Box-O Target Gene Expression in a Knowledge-Based Computational Model.

The phosphatidylinositol 3-kinase (PI3K) pathway is commonly activated in cancer. Tumors are potenti...

Jul 2018 PMID: 30030980

The effects of error-augmentation versus error-reduction paradigms in robotic therapy to enhance upper extremity performance and recovery post-stroke: a systematic review.

Despite upper extremity function playing a crucial role in maintaining one's independence in activit...

Jul 2018 PMID: 29973250

Inhalable Fucoidan Microparticles Combining Two Antitubercular Drugs with Potential Application in Pulmonary Tuberculosis Therapy.

The pulmonary delivery of antitubercular drugs is a promising approach to treat lung tuberculosis. T...

Jun 2018 PMID: 30966670

MR-Only Brain Radiation Therapy: Dosimetric Evaluation of Synthetic CTs Generated by a Dilated Convolutional Neural Network.

PURPOSE: This work aims to facilitate a fast magnetic resonance (MR)-only workflow for radiation the...

Jun 2018 PMID: 30108005

Machine metaphors and ethics in synthetic biology.

The extent to which machine metaphors are used in synthetic biology is striking. These metaphors con...

Jun 2018 PMID: 29862436

Assessing Effectiveness and Costs in Robot-Mediated Lower Limbs Rehabilitation: A Meta-Analysis and State of the Art.

Robots were introduced in rehabilitation in the 90s to meet different needs, that is, reducing the p...

Jun 2018 PMID: 29973978

Distinguishing True Progression From Radionecrosis After Stereotactic Radiation Therapy for Brain Metastases With Machine Learning and Radiomics.

PURPOSE: Treatment effect or radiation necrosis after stereotactic radiosurgery (SRS) for brain meta...

May 2018 PMID: 30353872

Mapping Cellular Polarity Networks Using Mass Spectrometry-based Strategies.

Cell polarity is a vital biological process involved in the building, maintenance and normal functio...

May 2018 PMID: 29782831

Physical Properties of the Extracellular Matrix of Decellularized Porcine Liver.

The decellularization of organs has attracted attention as a new functional methodology for regenera...

May 2018 PMID: 30674815

Evolution of upper limb kinematics four years after subacute robot-assisted rehabilitation in stroke patients.

To assess functional status and robot-based kinematic measures four years after subacute robot-assi...

Apr 2018 PMID: 29619890

ProvCaRe Semantic Provenance Knowledgebase: Evaluating Scientific Reproducibility of Research Studies.

Scientific reproducibility is critical for biomedical research as it enables us to advance science b...

Apr 2018 PMID: 29854241

Machine Learning Methods Improve Prognostication, Identify Clinically Distinct Phenotypes, and Detect Heterogeneity in Response to Therapy in a Large Cohort of Heart Failure Patients.

BACKGROUND: Whereas heart failure (HF) is a complex clinical syndrome, conventional approaches to it...

Apr 2018 PMID: 29650709

Predicting individual responses to the electroconvulsive therapy with hippocampal subfield volumes in major depression disorder.

Electroconvulsive therapy (ECT) is one of the most effective treatments for major depression disorde...

Apr 2018 PMID: 29615675

Pharmacological therapy selection of type 2 diabetes based on the SWARA and modified MULTIMOORA methods under a fuzzy environment.

Medication selection for Type 2 Diabetes (T2D) is a challenging medical decision-making problem invo...

Mar 2018 PMID: 29606521

A machine learning approach to the accurate prediction of monitor units for a compact proton machine.

PURPOSE: Clinical treatment planning systems for proton therapy currently do not calculate monitor u...

Mar 2018 PMID: 29500818

ANTENNA, a Multi-Rank, Multi-Layered Recommender System for Inferring Reliable Drug-Gene-Disease Associations: Repurposing Diazoxide as a Targeted Anti-Cancer Therapy.

Existing drug discovery processes follow a reductionist model of "one-drug-one-gene-one-disease," wh...

Mar 2018 PMID: 29993812

Social Robotics in Therapy of Apraxia of Speech.

Apraxia of speech is a motor speech disorder in which messages from the brain to the mouth are disru...

Mar 2018 PMID: 29713440

A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells.

AMPK is a serine threonine kinase composed of a heterotrimer of a catalytic, kinase-containing α and...

Feb 2018 PMID: 29491475

Public Health & Policy

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Assessment of Functional Phosphatidylinositol 3-Kinase Pathway Activity in Cancer Tissue Using Forkhead Box-O Target Gene Expression in a Knowledge-Based Computational Model.

The effects of error-augmentation versus error-reduction paradigms in robotic therapy to enhance upper extremity performance and recovery post-stroke: a systematic review.

Inhalable Fucoidan Microparticles Combining Two Antitubercular Drugs with Potential Application in Pulmonary Tuberculosis Therapy.

MR-Only Brain Radiation Therapy: Dosimetric Evaluation of Synthetic CTs Generated by a Dilated Convolutional Neural Network.

Machine metaphors and ethics in synthetic biology.

Assessing Effectiveness and Costs in Robot-Mediated Lower Limbs Rehabilitation: A Meta-Analysis and State of the Art.

Distinguishing True Progression From Radionecrosis After Stereotactic Radiation Therapy for Brain Metastases With Machine Learning and Radiomics.

Mapping Cellular Polarity Networks Using Mass Spectrometry-based Strategies.

Physical Properties of the Extracellular Matrix of Decellularized Porcine Liver.

Evolution of upper limb kinematics four years after subacute robot-assisted rehabilitation in stroke patients.

ProvCaRe Semantic Provenance Knowledgebase: Evaluating Scientific Reproducibility of Research Studies.

Machine Learning Methods Improve Prognostication, Identify Clinically Distinct Phenotypes, and Detect Heterogeneity in Response to Therapy in a Large Cohort of Heart Failure Patients.

Predicting individual responses to the electroconvulsive therapy with hippocampal subfield volumes in major depression disorder.

Pharmacological therapy selection of type 2 diabetes based on the SWARA and modified MULTIMOORA methods under a fuzzy environment.

A machine learning approach to the accurate prediction of monitor units for a compact proton machine.

ANTENNA, a Multi-Rank, Multi-Layered Recommender System for Inferring Reliable Drug-Gene-Disease Associations: Repurposing Diazoxide as a Targeted Anti-Cancer Therapy.

Social Robotics in Therapy of Apraxia of Speech.

A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells.

A computer vision-based system for monitoring Vojta therapy.

Predictors of activities of daily living outcomes after upper limb robot-assisted therapy in subacute stroke patients.

Critiquing the Reasons for Making Artificial Moral Agents.

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