Endocrinology

Steroids

Latest AI and machine learning research in steroids for healthcare professionals.

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Association of Vitamin D Deficiency and Thyroid Function in Postmenopausal Women.

Although there are reports of vitamin D (VitD) insufficiency in immune-mediated hypothyroidism, an association between VitD and thyroid-stimulating hormone (TSH) levels has yet to be shown. We aim to examine VitD and TSH levels among postmenopausal women, as both conditions are more prevalent in elderly women. The clinic records of postmenopausal women during their routine maintenance visits wer...

Dec 22 2016 28101471

Methotrexate-associated primary hepatic malignant lymphoma following hepatectomy: A case report.

INTRODUCTION: Recently, immunosuppressant-associated malignant lymphoma (ML) cases have been increasing along with the development of several effective immunosuppressant drugs for rheumatoid arthritis (RA). Among methotrexate (MTX)-associated lymphoproliferative disorders, primary hepatic lymphoma (PHL) in patients with RA following surgical resection has not been reported previously.

Dec 21 2016 28076752
Cytokine Changes following Acute Ethanol Intoxication in Healthy Men: A Crossover Study.

Alcohol is a known modulator of the innate immune system. Owing to the absence of human studies, alcohol's effect on circulating cytokine profile rema...

Dec 20 2016 28090151
ANA-Negative Presentation of SLE in Man with Severe Autoimmune Neutropenia.

. Systemic lupus erythematosus (SLE) is a chronic, inflammatory, connective tissue disease that commonly affects the joints and a variety of organs du...

Dec 19 2016 28077945
Caloric restriction and IGF-I administration promote rabbit fecundity: Possible interrelationships and mechanisms of action.

The aim of these in vivo and in vitro studies was to examine the influence of caloric restriction (CR), and the administration of insulin-like growth ...

Dec 18 2016 28166977
A case of rapid amelioration of hepatitis C virus-associated cryoglobulinemic membranoproliferative glomerulonephritis treated by interferon-free directly acting antivirals for HCV in the absence of immunosuppressant.

Mixed cryoglobulinemic syndrome, which is a systemic vasculitis characterized by the immune complex deposition in small- and medium-sized arteries and...

Nov 21 2016 28509128
Adequate tacrolimus concentration for myasthenia gravis treatment.

BACKGROUND AND PURPOSE: A single, oral dose of 3 mg/day tacrolimus, approved for myasthenia gravis (MG) treatment in Japan, was shown to reduce steroi...

Nov 7 2016 28102047
Histone deacetylase 2 is decreased in peripheral blood pro-inflammatory CD8+ T and NKT-like lymphocytes following lung transplant.

BACKGROUND AND OBJECTIVE: Immunosuppression therapy following lung transplantation fails to prevent chronic rejection in many patients, which is assoc...

Nov 6 2016 28102966
The Occurrence of Subclinical Hypercortisolism and Osteoporosis in Patients with Incidentally Discovered Unilateral and Bilateral Adrenal Tumors.

BACKGROUND: Adrenal incidentalomas (AI) are clinically silent adrenal masses that are detected incidentally during imaging procedures performed for un...

Nov 2 2016 28670192
Transforming Growth Factor β1 (TGF-β1) in the Sera of Postmenopausal Osteoporotic Females.

BACKGROUND: Postmenopausal osteoporosis is a major cause of morbidity in postmenopausal females. Transforming growth factor β1 (TGF-β1) and interleuki...

Oct 22 2016 28123435
Korean Red Ginseng extract induces angiogenesis through activation of glucocorticoid receptor.

BACKGROUND: Our previous studies have demonstrated that ginsenoside-Rg1 can promote angiogenesis and through activation of the glucocorticoid recept...

Sep 8 2016 29021694
Neuro-endocrine effects of aqueous extract of (Linn.) leaf in male Wistar rat model of cyclophosphamide-induced reproductive toxicity.

Cyclophosphamide (CP) is a widely used cytotoxic alkylating agent with antitumor and immunosuppressant properties that is associated with various form...

Aug 3 2016 28959584
Prediction of selective estrogen receptor beta agonist using open data and machine learning approach.

BACKGROUND: Estrogen receptors (ERs) are nuclear transcription factors that are involved in the regulation of many complex physiological processes in ...

Jul 18 2016 27486309
Development and characterization of methoxy poly(ethylene oxide)--poly(ε-caprolactone) (PEO--PCL) micelles as vehicles for the solubilization and delivery of tacrolimus.

Tacrolimus is a potent immunosuppressant; however, it suffers from several problems such as poor water solubility (4-12 μg/mL), low and variable oral ...

Jul 1 2016 28344477
Automatic detection of osteoporosis based on hybrid genetic swarm fuzzy classifier approaches.

OBJECTIVES: This study proposed a new automated screening system based on a hybrid genetic swarm fuzzy (GSF) classifier using digital dental panoramic...

Jun 8 2016 27186991
Force degradation behavior of glucocorticoid deflazacort by UPLC: isolation, identification and characterization of degradant by FTIR, NMR and mass analysis.

In this investigation, sensitive and reproducible methods are described for quantitative determination of deflazacort in the presence of its degradati...

Feb 20 2016 28276670
Outcome of Inhaler Withdrawal in Patients Receiving Triple Therapy for COPD.

BACKGROUND: The purpose of this study was to document outcomes following withdrawal of a single inhaler (step-down) in chronic obstructive pulmonary d...

Dec 31 2015 26770231
Construction and characterization of recombinant adenovirus carrying a mouse TIGIT-GFP gene.

Recombinant adenovirus vector systems have been used extensively in protein research and gene therapy. However, the construction and characterization ...

Dec 29 2015 26782515
Evaluation of leflunomide for the treatment of BK viremia and biopsy proven BK nephropathy; a single center experience.

BACKGROUND: BK virus reactivation is a significant complication following renal transplantation that can result in graft failure. Reduction of immunos...

Dec 23 2015 27047808
AHCC Activation and Selection of Human Lymphocytes via Genotypic and Phenotypic Changes to an Adherent Cell Type: A Possible Novel Mechanism of T Cell Activation.

Active Hexose Correlated Compound (AHCC) is a fermented mushroom extract and immune supplement that has been used to treat a wide range of health cond...

Dec 15 2015 26788109
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