Surgery

Latest AI and machine learning research in surgery for healthcare professionals.

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GEN-Guard: Correcting Generalization Failures for Deployable Federated Surgical AI

Federated Learning (FL) in surgical video AI enables collaborative model training without sharing sensitive data. However, standard evaluation practices - selecting the "best" global model based only on validation data from participating hospitals - can lead to suboptimal deployment choices. We identify this critical failure mode as performance leakage, where the selected model overfits internal f...

Jun 18 2026 2606.20303v1

Balanced Twins: Causal Inference on Time Series with Hidden Confounding

Accurately estimating treatment effects in time series is essential for evaluating interventions in real-world applications, especially when treatment assignment is biased by unobserved factors. In many practical settings, interventions are adopted at different times across individuals, leading to staggered treatment exposure and heterogeneous pre-treatment histories. In such cases, aggregating ou...

Jun 17 2026 2606.18969v1
Training LLMs with Reinforcement Learning over Digital Twin Representations for Reasoning-Intensive Surgical VideoQA

Surgical video question answering requires multi-step reasoning across semantic, spatial, and temporal dimensions. Existing methods architecturally co...

Jun 15 2026 2606.17279v1
Structure-aware Knowledge-guided Heterogeneous Mamba for Zygomaticomaxillary Suture Assessment

The Zygomaticomaxillary Suture is a key circummaxillary structure that connects the zygomatic bone and the maxilla, which serves as a primary site of ...

Jun 15 2026 2606.16749v1
Beyond the Blood Draw: Explainable Machine Learning for Non-Invasive Dysglycemia Risk Screening

Dysglycemia, encompassing both prediabetes and diabetes, affects huge numbers of adults worldwide, yet many of them remain undiagnosed. We developed a...

Jun 14 2026 2606.16056v1
A Lightweight Fiducial-Based Pipeline for 3D Hyperspectral Mapping of ex-vivo Lumpectomy Specimens

Hyperspectral Imaging (HSI) is a promising modality for intraoperative assessment of resection margins in Breast-Conserving Surgery (BCS), but its cli...

Jun 12 2026 2606.14534v1
Computer Vision for Real-Time Anatomical Navigation in Neurosurgery: First-in-Human Clinical Evaluation and Iterative Development (IDEAL Stage 1)

Introduction: Precise anatomical navigation is fundamental to safe endoscopic pituitary surgery, a high-stakes procedure characterised by a challengin...

Single-camera, calibration-free gaze estimation using corneal reflections

Background. Mice make substantial eye movements during head-fixed visual stimulation, and uncorrected gaze shifts corrupt receptive field measurements...

A Three-Tier Operational Benchmark for Evaluating Large Language Models on Hospital Medication Safety

Objective. To introduce PsiBench, a clinically validated medication-safety benchmark for evaluating large language models (LLMs) against the standards...

An Explainable Multimodal AI Framework with Reinforcement Learning for Post-Surgical Clinical Decision Support

Post-surgical adverse outcomes, including mortality, intensive care readmission, and complications, remain major challenges for clinical decision-maki...

A hierarchical clinical fusion transformer model for personalized opioid treatment: Development and validation in diabetic surgical patients

Background Machine learning (ML) models are increasingly used to predict adverse outcomes after surgery. However, most rely on static patient characte...

Beyond Convolution: Advancing Hypergraph Neural Networks with Hypergraph U-Nets

Convolutions have successfully transitioned from image processing to the complex realm of non-Euclidean higher-order domains, particularly in hypergra...

Jun 8 2026 2606.09051v1
iMaC: Translating Actions into Motion and Contact Images for Embodied World Models

Embodied world models have emerged as a pivotal paradigm for visual robotic decision-making and interactive environment simulation. However, conventio...

Jun 8 2026 2606.09813v1
Routine laboratory trajectories encode the onset of organ-level complications in cancer

Routine laboratory panels drawn during cancer treatment constitute longitudinal physiological recordings of organ function, yet their temporal structu...

Jun 7 2026 2606.08538v1
Immediate to longer-term neurophysiological impact of acute neural network disruption

Despite substantial interest in how neural systems recover over time after acute neurological events, there is a dearth of longitudinal assessment fro...

EXHEART: A Fairness-Aware Explainable Stacked Ensemble for Cardiovascular Disease Classification with Cross-Instrument Disparity Attribution

Background: Machine learning models trained on population health surveys offer scalable tools for cardiovascular screening, but recurring methodologic...

Real-time Computer Vision Assisted Navigation for Endoscopic Pituitary Surgery: Iterative Development and Comparative Preclinical Evaluation

Background Endoscopic pituitary surgery involves navigating high-stakes anatomy where complications, such as carotid artery injury, cause devastating ...

Exploring the Interpretability of AI Decision Support Systems for Surgical Anatomy Recognition

Artificial intelligence (AI) decision support systems for surgery hold promise but face barriers to adoption, particularly around the interpretability...

Sensitive Glioma Detection and Recurrence Monitoring Using a Machine Learning Model Based on Circulating Monocytes

Background: Non-invasive diagnosis, reliable recurrence surveillance remain critical unmet needs in gliomas. Glioma induces profound systemic immune a...

Deconvolution improves cryo-EM maps

With technological advancements in recent years, single particle cryogenic electron microscopy (cryo-EM) has become a major methodology for structural...

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