Transplantation

Latest AI and machine learning research in transplantation for healthcare professionals.

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Surface Mounted Metal-Organic Frameworks for Advanced Sensing: Construction Strategies, Recent Applications, and Emerging Opportunities With Artificial Intelligence.

Sensors play a vital role in modern production and daily life, where high sensitivity, selectivity, and device integration are increasingly required. Metal-organic frameworks (MOFs) have emerged as highly promising materials for sensing applications owing to their high porosity, structural diversity, tunable pore architectures, and tailorable host-guest interactions. However, the practical deploym...

Jul 6 2026 42409754

Explainable AI for employee turnover prediction: a SHAP-based intelligent analytics approach.

Employee turnover prediction is a critical challenge in human resource management. Existing studies emphasise predictive accuracy but generally treat interpretability as an afterthought, and applications of SHapley Additive exPlanations (SHAP) in this domain typically stop at single-level feature importance without reporting threshold calibration, subgroup fairness, or external validation. This st...

Jul 6 2026 42409883
A population-based retrospective machine learning study of COVID-19 severity using integrated clinical and viral genomic data in Jiangsu Province, China.

BACKGROUND: As coronavirus disease 2019 (COVID-19) has transitioned into an endemic phase characterized by sustained transmission and widespread hybri...

Jul 6 2026 42410338
AI-driven neoantigen identification: a comprehensive review from somatic variant calling to T cell recognition.

BACKGROUND: Neoantigens-tumor-specific peptides generated by somatic mutations-are central targets of effective anticancer T cell immunity and underpi...

Jul 6 2026 42410432
A Novel Dosing Strategy for Tacrolimus in Lung Transplant Recipients: Integrating Machine Learning with Population Pharmacokinetic Analysis.

BACKGROUND: Integrating machine learning (ML) with population pharmacokinetic (PPK) modeling may improve therapeutic drug monitoring predictions. METH...

Jul 6 2026 42397045
Recent Advances in Organic Donor-Acceptor Two-Photon Absorption Materials: Mechanisms, Molecular Design, and Applications.

Organic materials have been widely recognized as highly promising candidates for two-photon absorption (TPA) applications owing to their strong optica...

Jul 5 2026 42402814
Vascular reprogramming in cancer: engineering the tumor microenvironment.

Tumor vasculature has traditionally been viewed as structurally and functionally abnormal and, therefore, is primarily targeted for inhibition. Howeve...

Jul 5 2026 42402079
Organoid-AI platforms need integrated governance in drug discovery.

Organoid-AI platforms are becoming decision systems in drug discovery, not just combined tools. They shape compound prioritisation, toxicity assessmen...

Jul 4 2026 42401253
Deep Learning-Based Standard Section Recognition and Multi-Organ Segmentation in Upper Abdominal Ultrasound.

OBJECTIVE: To develop and evaluate deep learning models for upper abdominal ultrasound standard section recognition and downstream multi-organ segment...

Jul 4 2026 42399171
Tissue identity is the dominant determinant of cross-species transferability of a porcine developmental programme.

BACKGROUND: Reproducibility and cross-species translation using the domestic pig (Sus scrofa) are limited by the lack of a standardised molecular fram...

Jul 4 2026 42399791
TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review).

The poor prognosis of high‑grade gliomas, such as glioblastoma, is largely driven by a notably immunosuppressive tumor microenvironment (TME), wherein...

Jul 3 2026 42396649
tmGNN-XAI: An Explainable Graph Neural Network Tool for Predicting Electronic Properties of Transition Metal Complexes from SMILES.

Predicting the electronic properties of transition metal complexes (TMCs) from 2D molecular graphs remains challenging; organic-trained property model...

Jul 3 2026 42398017
A dynamic machine learning model for predicting organ transplant success to optimize donor organ utilization and reduce costs.

BACKGROUND: Organ recovery for transplantation costs approximately $40,000 per donor, yet nearly 20% of recovered kidneys ultimately go unused. Static...

Jul 3 2026 42394433
QSAR in the Browser: An Interactive Cheminformatics Web Application.

Cheminformatic analysis has been an active field for almost half a century, with considerable innovation accelerating drug discovery. However, the req...

Jul 3 2026 42397292
Exploring Informal Caregivers' Perception of the Olera Digital Caregiving Assistance Platform for Dementia Care: Mixed Methods Evaluation Study.

BACKGROUND: Informal caregivers of people living with dementia often experience high rates of caregiver burnout while providing care. Although there a...

Jul 3 2026 42398038
Multi-omics and metabolic flux modeling reveal that macrophage CYP27A1-derived 26-hydroxycholesterol drives immunosuppression and cancer malignancy.

Emerging evidence indicates that aberrant cholesterol metabolism in macrophages plays a role in tumorigenesis, however, how specific metabolites relea...

Jul 3 2026 42399552
Beyond native sequence recovery: Improved modeling of the sequence-energy landscape of protein structures.

Computational protein design using machine learning models has advanced rapidly since the introduction of AlphaFold2. There is now a suite of tools th...

Jul 2 2026 42391398
Leveraging multimodal cancer immunotherapy to amplify the efficacy of oncolytic viruses.

Oncolytic viruses (OVs) represent a versatile platform for cancer immunotherapy, capable of selectively infecting and lysing tumor cells while trigger...

Jul 2 2026 42393779
An EEG-based hybrid machine learning approach for CT scan triage in mild traumatic brain injury.

Mild traumatic brain injury (mTBI) frequently prompts computed tomography (CT) imaging in emergency departments, despite a high proportion of negative...

Jul 2 2026 42393204
Dual-mode analysis of ischemic stroke based on urine SERS spectra and carotid B-ultrasound.

Achieving noninvasive high-frequency monitoring of ischemic stroke (IS) remains a major clinical challenge for timely intervention and precise seconda...

Jul 1 2026 42384817
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