Transplantation

Latest AI and machine learning research in transplantation for healthcare professionals.

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Human Retinal Organoids in Therapeutic Discovery: A Review of Applications.

Human embryonic stem cells (hESCs)- and induced pluripotent stem cells (hiPSCs)-derived retinal organoids (ROs) are three-dimensional laminar structures that recapitulate the developmental trajectory of the human retina. The ROs provide a fascinating tool for basic science research, eye disease modeling, treatment development, and biobanking for tissue/cell replacement. Here we review the previous...

Jan 1 2023 37608005

Interleukin-6 and interleukin-8 levels in children with aplastic anemia and its correlation with disease severity and response to immunosuppressive therapy.

BACKGROUND: Aplastic anemia (AA) is an uncommon condition characterized by pancytopenia and hypocellular bone marrow. Interleukin (IL)-6 and IL-8 have been shown to inhibit myelopoiesis and are major mediators of tissue damage. The primary goal of this study was to determine the IL-6 and IL-8 levels in children with AA, as well as their relationship to illness severity and immunosuppressive medica...

Jan 1 2023 38358144
Estimation of Mycophenolic Acid Exposure in Chinese Renal Transplant Patients by a Joint Deep Learning Model.

BACKGROUND: To predict mycophenolic acid (MPA) exposure in renal transplant recipients using a deep learning model based on a convolutional neural net...

Dec 1 2022 36070781
Reducing Geometric Uncertainty in Computational Hemodynamics by Deep Learning-Assisted Parallel-Chain MCMC.

Computational hemodynamic modeling has been widely used in cardiovascular research and healthcare. However, the reliability of model predictions is la...

Dec 1 2022 36166284
Neural Network Approaches for Soft Biological Tissue and Organ Simulations.

Given the functional complexities of soft tissues and organs, it is clear that computational simulations are critical in their understanding and for t...

Dec 1 2022 36193891
[Automatic Delineation of Clinical Target Volume and Organ at Risk by Deep Learning for Prostate Cancer Adaptive Radiotherapy].

Adaptive radiotherapy can modify the treatment plan online based on the clinical target volume (CTV) and organ at risk (OAR) contours on the cone-beam...

Nov 30 2022 36597401
Artificial intelligence-driven prediction of multiple drug interactions.

When a drug is administered to exert its efficacy, it will encounter multiple barriers and go through multiple interactions. Predicting the drug-relat...

Nov 19 2022 36168896
Dynamic single-photon 3D imaging with a sparsity-based neural network.

Deep learning is emerging as an important tool for single-photon light detection and ranging (LiDAR) with high photon efficiency and image reconstruct...

Oct 10 2022 36258323
HLAncPred: a method for predicting promiscuous non-classical HLA binding sites.

Human leukocyte antigens (HLA) regulate various innate and adaptive immune responses and play a crucial immunomodulatory role. Recent studies revealed...

Sep 20 2022 35580839
A chronotherapeutics-applicable multi-target therapeutics based on AI: Example of therapeutic hypothermia.

Nowadays, the complexity of disease mechanisms and the inadequacy of single-target therapies in restoring the biological system have inevitably instig...

Sep 20 2022 36088545
Robotic Kidney Transplantation Under Regional Hypothermia.

The technique of robotic kidney transplantation (RKT) under regional hypothermia is being described. It may be performed in all patients requiring kid...

Sep 1 2022 36154452
A Novel Microsurgical Robot: Preliminary Feasibility Test in Ophthalmic Field.

PURPOSE: This study investigated the feasibility and potential advantage of using a new microsurgical teleoperated robot, Symani Surgical System, in t...

Aug 1 2022 35976656
PySio: A New Python Toolbox for Physiological Signal Visualization and Feature Analysis.

In physiological signal analysis, identifying meaningful relationships and inherent patterns in signals can provide valuable information regarding sub...

Jul 1 2022 36083937
Efficacy of robot-assisted core decompression combined with human umbilical cord-derived mesenchymal stem cell transplantation for osteonecrosis of the femoral head.

OBJECTIVE: The aim of this paper was to evaluate the effects of robot-assisted core decompression combined with human umbilical cord-derived mesenchym...

Jun 1 2022 35776018
Artificial Intelligence in Kidney Transplantation: A Scoping Review.

Artificial Intelligence (AI) technologies are increasingly being used to enhance kidney transplant outcomes. In this review, we explore the use of AI ...

May 25 2022 35612067
Robotic Kidney Transplant: The Modern Era Technical Revolution.

Since the mid 20th century, transplantation has been a fast-developing field of contemporary medicine. The technical aspects of transplant operations ...

Mar 1 2022 34288638
Active disease-related compound identification based on capsule network.

Pneumonia, especially corona virus disease 2019 (COVID-19), can lead to serious acute lung injury, acute respiratory distress syndrome, multiple organ...

Jan 17 2022 35057581
Transit Time Flow Measurement in Robotic Totally Endoscopic Coronary Artery Bypass: What Do the Numbers Mean?

OBJECTIVE: Transit time flow measurement (TTFM) is valuable for assessing intraoperative graft patency in coronary artery bypass surgery (CAB). The si...

Jan 1 2022 35499921
Role of Artificial Intelligence in Cancer Diagnosis and Drug Development.

Cancer is a vast form of the disease that can begin in almost any organ or tissue of the body when abnormal cells grow uncontrollably and attack nearb...

Jan 1 2022 35249476
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