Latest AI and machine learning research in transplantation for healthcare professionals.
BACKGROUND: Acute lung injury and its severe form, acute respiratory distress syndrome (ARDS), represent life-threatening conditions with high mortality rates. Since the lung is the primary target organ in systemic inflammatory conditions like sepsis, this study aimed to identify key regulatory genes by analyzing systemic inflammation-related transcriptomic data, and to explore their roles in lung...
BACKGROUND AND OBJECTIVES: Adults with sickle cell disease (SCD) are at risk of decline in brain health and cognition, even without clinical stroke. SCD-related changes on MRI include brain atrophy and T2 fluid attenuated inversion recovery (FLAIR) white matter hyperintensity (WMH) growth. Hematopoietic stem cell transplant (HSCT) can be curative, but conditioning regimens risk new complications, ...
Structure-based virtual screening (SBVS) is a widely used approach in in silico drug discovery, requiring a receptor structure or binding site to pred...
The Organ Utilisation Group was established to address barriers in solid organ transplantation and improve patient outcomes across the United Kingdom....
PURPOSE OF REVIEW: Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, producing durable responses across multiple malignancies. Howe...
This article investigates a dissipative disturbance-estimator (DDE)-based neuro-adaptive integral sliding-mode control (ISMC) for multiple autonomous ...
Artificial intelligence (AI)-based risk prediction is increasingly implemented in clinical care, but randomized evidence on communication and shared d...
BACKGROUND: Reactive oxygen species (ROS) are critical regulators of tumor development and progression, yet their clinical significance and cellular m...
Predicting the clinical efficacy of Natural Killer (NK) cell immunotherapies remains challenging due to functional heterogeneity within effector popul...
Corneal blindness affects millions worldwide, yet donor tissue remains insufficient to meet clinical demand. In this context, 3D bioprinting has emerg...
Chronic tendinopathy is typified by persistent tendon-associated pain, transmitted by local nociceptive neurons. However, the regulatory function of s...
BACKGROUND: The transfusion of blood components remains a cornerstone in the management of hematological and onco-hematological diseases. Effective bl...
Visualizing genome organization and transcriptional dynamics with spatial and temporal precision in living cells is essential for elucidating gene reg...
PURPOSE: Internal anatomical motion challenges precise radiation delivery during external beam radiotherapy. Estimating and compensating for anatomica...
Emerging evidence highlights hypoxia-responsive long non-coding RNAs (lncRNAs) as potential modulators in tumor biology. In this study, we explored th...
The increasing focus on the United Nations Sustainable Development Goals and on global net-zero emission targets has intensified the search for renewa...
BACKGROUND: The prognosis for patients with glioblastoma (GBM) remains extremely poor, a challenge largely attributable to the complex nature of its m...
BACKGROUND: Accurate risk stratification of biliary complications (BCs) after liver transplantation (LT) remains challenging. This study aimed to deve...
Neural interfacing materials must deliver exceptional electrochemical performance, while integrating safely with the central nervous system. In this s...
Early non-invasive prediction of cardiovascular risk is an essential prerequisite for preventive medicine, especially in resource-limited settings. Re...