Latest AI and machine learning research in transplantation for healthcare professionals.
T-cell bispecific antibodies (TCBs), a specialized subclass of bispecific antibodies (BsAbs), are engineered to simultaneously engage T cells and tumor cells by binding two distinct antigens-or two epitopes on a single antigen-thereby redirecting cytotoxic T lymphocytes to eliminate malignant cells. These agents enhance anti-tumor immunity through dual mechanisms: direct activation of T cell recep...
Tissue engineering, rooted in cell biology and materials science, focuses on repairing or replacing injured tissues and organs, offering groundbreaking solutions in regenerative medicine. Although progress has been made in scaffold design, growth factor utilization, and stem cell applications, challenges such as prolonged production timelines, high costs, and unpredictable tissue outcomes persist....
Organ transplantation remains a gold-standard intervention for numerous end-stage organ failure diseases. However, allograft rejection is still a barr...
PURPOSE: To evaluate the accuracy of automatic surface tracking registration with a smartphone augmented reality (AR) guidance system for percutaneous...
Cancer-associated fibroblasts (CAFs) are major stromal components of the tumor microenvironment (TME) and play diverse roles in gastrointestinal (GI) ...
BACKGROUND: Ammonia, which was traditionally regarded as a metabolic by-product, has more recently emerged as a crucial regulator of tumor metabolism ...
PURPOSE OF REVIEW: Asthma continues to pose a serious global health issue affecting billions of people and causing significant morbidity. It is immuno...
Deep learning and prior-image-guided cross modality motion reconstruction methods have recently en abled faster acquisition time and lower artifacts i...
Across Africa, substantial investment has built national health information systems (HISs), including the surveillance platforms, reporting tools, and...
The superior image quality and excellent contrast offered by Magnetic Resonance Imaging (MRI) make it an ideal tool for guiding interventional procedu...
With the emergence of powerful deep learning-based tools, computational protein design has become a widely accessible technique. Nowadays, it is possi...
Sepsis is a life-threatening organ malfunction induced by the host's abnormal reaction to infection. Sepsis can induce cellular senescence, thereby ex...
σ-p hyperconjugation is identified as an effective molecular lever for regulating the excited-state behavior and donor characteristics of covalent org...
Protein therapeutics offer unparalleled specificity and immediate bioactivity for addressing complex pathologies; however, their vast therapeutic pote...
BACKGROUND: New-onset atrial fibrillation (NOAF) is a common cardiovascular complication in critically ill patients and is consistently associated wit...
BACKGROUND: Thyroid carcinoma (TC) presents a rising global incidence, with a subset of cases progressing aggressively despite standard therapies. The...
The female reproductive system, including the endometrium, placenta, ovary, cervix, and fallopian tube, plays a critical role in conception, implantat...
Both conventional and next-generation probiotics play a crucial role in maintaining host homeostasis. They modulate insulin sensitivity, immune-regula...