Latest AI and machine learning research in transplantation for healthcare professionals.
The development of PVA hydrogels for cartilage repair is limited by the challenge of simultaneously combining high mechanical strength with high water content. To address this, a "Dual-Stage Temperature-Controlled Crystallization Quenching Method" is proposed. The approach precisely regulates crystallization kinetics, enabling meticulous control over the gel network topology. The obtained hydrogel...
Synergizing radiotherapy (RT) with immune checkpoint inhibitors has emerged as a promising strategy for solid tumors. RT acts as a potent immunomodulator, capable of functioning as an in situ vaccine through the induction of immunogenic cell death and activation of innate immune sensing, thereby promoting DC maturation and CD8+ T cell responses. However, RT also triggers counter-regulatory immunos...
Thymic epithelial tumors (TETs) are rare and heterogeneous malignancies whose aggressive epithelial states and microenvironmental organization remain ...
Long-term spaceflight poses substantial challenges to human physiology, with the liver being highly susceptible due to its central metabolic role. To ...
INTRODUCTION: Artificial intelligence (AI) is a branch of technology enabling machines to emulate complex human skills; it can also entail problem-sol...
Sarcopenia is common in type 2 diabetes (T2D), but whether sarcopenia-associated transcriptomic features can be detected in diabetic skeletal muscle r...
Artificial intelligence has accelerated epitope and antigen discovery, but prediction alone cannot determine vaccine readiness. Translational design r...
INTRODUCTION: Artificial intelligence (AI) is increasingly recognized as a transformative paradigm within transplantation medicine, offering advanced ...
Per- and polyfluoroalkyl substances (PFAS), particularly perfluorooctane sulfonate (PFOS), persist in humans and have been associated with cardiovascu...
Unconventional water, as an important supplement to traditional water sources, plays a crucial role in promoting water resources spatial equilibrium (...
Aging is the primary risk factor for chronic disease and is characterized by profound structural and architectural remodeling of human tissues. Here, ...
The adrenomedullin receptor signaling pathway plays a crucial role in tumor progression, yet its comprehensive implication in hepatocellular carcinoma...
Keratinocyte carcinoma (KC) places a considerable and growing burden on healthcare systems. Given the KC population's heterogeneity, tailored clinical...
BACKGROUND: Antibody-mediated rejection (AMR) is the main driver of late kidney allograft loss. Anti-HLA donor-specific antibodies (DSA) are strongly ...
OBJECTIVE: This study aimed to identify the factors contributing to Prolonged Length of Stay (PLOS) in intensive care units for sepsis patients combin...
Fibrotic interstitial lung diseases (ILDs) are classified into histopathological patterns by the idiopathic interstitial pneumonia (IIP) classificatio...
Pain management remains a significant challenge in pediatric care, where pain is frequently under-assessed and undertreated. Artificial intelligence i...
OBJECTIVES: Sudden cardiac arrest is a leading cause of mortality in Canada (40,000 treatable deaths annually). Despite the benefits of 9-1-1 telecomm...
Cancer immunotherapy has transformed the treatment landscape across multiple malignancies; however, durable responses remain limited to a subset of pa...
Tumor immunotherapy has emerged as a transformative strategy for cancer treatment. However, its clinical efficacy remains limited by the immunosuppres...