Transplantation

Latest AI and machine learning research in transplantation for healthcare professionals.

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Preclinical and Virtual Models of Mucosal Melanoma: Bridging Translational Gaps in a Rare and Lethal Cancer.

Mucosal melanoma (MM) is a rare and lethal subtype of melanoma, disproportionately affecting Asian populations and exhibiting distinct clinicopathological and genetic features compared to cutaneous melanoma (CM). Often diagnosed at advanced stages, MM shows poor responses to conventional therapies, and no standardized treatment regimen currently exists. Progress in preclinical modeling, including ...

Jul 1 2026 42261051

Personalized eye protection for head CT organ-based tube current modulation: A deep learning approach to derive 3D eyeball models from a single-view topogram.

BACKGROUND: The lens of the eye is highly radiosensitive, yet personalized shielding during head CT remains challenging due to the lack of a rapid, pre-scan localization method. PURPOSE: To develop and validate a deep learning solution that enables automated, patient-specific eye protection by generating a precise 3D eyeball model directly from a single-view topogram. METHODS: Our two-stage approa...

Jul 1 2026 42338069
Explainable machine learning for patient-specific quality assurance in intensity-modulated radiotherapy based on anatomical structures.

BACKGROUND: Patient-specific quality assurance (PSQA) plays a pivotal role in intensity-modulated radiotherapy (IMRT) to ensure accurate dose delivery...

Jul 1 2026 42340103
Identification of preeclampsia-associated immune-related risk loci in the Chinese population.

OBJECTIVE: Preeclampsia, the most severe hypertensive disorder of pregnancy, is the leading cause of maternal death. While genetic factors are recogni...

Jul 1 2026 42362264
Advances and prospects in cell therapy for cancer: explorations from T cells to stem cells.

The increasing global burden of cancer necessitates innovative therapeutic strategies. Cell therapy represents a major breakthrough in oncology, evolv...

Jul 1 2026 42380095
Metabolic reprogramming of myeloid cells in cancer: from lactate-NAMPT axis to AI-guided therapeutics.

Myeloid cells-including macrophages, monocytes, neutrophils and dendritic cells-are metabolically plastic sentinels that shape the tumor microenvironm...

Jul 1 2026 42380285
Integrative Genomic and Clinical Profiling of Colorectal Cancer Liver Metastases to Guide Personalized Surgery and Liver Transplantation.

BACKGROUND/AIM: Colorectal cancer liver metastases (CRLM) remain a leading cause of cancer-related mortality. Although hepatic resection is the only e...

Jul 1 2026 42373221
Early metabolic trajectory and sedation strategy in V-V ECMO for severe pneumonia: a multicenter cohort study.

BACKGROUND: Prognostic assessment in patients with severe pneumonia requiring veno-venous extracorporeal membrane oxygenation (V-V ECMO) has tradition...

Jun 30 2026 42374899
Autonomous robotic execution of nonlinear toolpaths for geometry-matched osteotomy in tooth autotransplantation: an in vitro study.

Tooth autotransplantation requires recipient socket preparation that matches donor root morphology while preserving surrounding bone. We developed an ...

Jun 30 2026 42380089
Generative Artificial Intelligence and 3D Printing in Craniomaxillofacial Deformities: A Narrative Review of Emerging Synergies.

Craniomaxillofacial deformities are primarily caused by congenital anomalies, trauma, or postoperative defects following tumor resection, involving bo...

Jun 30 2026 42377919
Discovery of biomarkers for primary Sj ögren's syndrome based on multi-omics data, construction of diagnostic models, and clinical correlation analysis.

OBJECTIVE: Primary Sjogren's syndrome(pSS) exhibits significant clinical heterogeneity, which poses challenges for accurately assessing disease activi...

Jun 29 2026 42374508
Compact Modeling of Pd-MoS2 Self-rectifying RRAM based on modulated Schottky barrier equation.

The rapid growth of artificial intelligence computing has intensified the demand for energyefficient hardware accelerators capable of large-scale matr...

Jun 29 2026 42372762
OracleScreen-LILRB4: machine learning-guided discovery of myeloid immune checkpoint binders validated in patient-derived cells.

The identification of small molecule modulators of immune checkpoint proteins remains a significant challenge in drug discovery due to the flat, featu...

Jun 29 2026 42372925
Explainable machine learning identifies small high-performance gene signatures from full transcriptomes in human liver preservation cohorts.

Transcriptomic studies of liver preservation and ischemia-reperfusion injury (IRI) often report large gene lists that are difficult to translate into ...

Jun 29 2026 42374126
Mapping the intellectual landscape of malaria drug repurposing: a systematic analysis of the 51 most cited studies.

BACKGROUND: The escalating threat of Plasmodium falciparum resistance to artemisinin-based therapies necessitates accelerated drug development. Drug r...

Jun 29 2026 42374402
Identification of distinct subgroups in Chinese patients with Behçet's syndrome via cluster analysis of immune cells and clinical features.

OBJECTIVES: This study aimed to use machine learning to explore Behçet's syndrome (BS) heterogeneity by integrating immunocyte subpopulations and clin...

Jun 29 2026 42366396
Echocardiographic assessment in arterial hypertension: a contemporary narrative review.

Arterial hypertension remains the leading modifiable cause of cardiovascular morbidity and mortality resulting in characteristic changes in cardiac st...

Jun 29 2026 42366420
The functional relevance of human leukocyte antigens in the development of cord blood derived advanced cellular therapies: A new direction of public cord blood banks.

CBUs have been applied as alternative source of HSCs transplantation. The increasing preference for haploidentical HSC transplantation has resulted in...

Jun 27 2026 42364409
Development and external validation of an interpretable machine learning model for predicting prolonged postoperative ICU length of stay in coronary artery bypass grafting patients using MIMIC-IV 3.1 and eICU-CRD 2.0.

BACKGROUND: Prolonged postoperative intensive care unit (ICU) length of stay (LOS) after coronary artery bypass grafting (CABG) drives resource use ye...

Jun 27 2026 42365267
A dual-contrast deep learning model for automated assessment of sarcopenia using MRI.

PURPOSE: To develop a dual-contrast deep-learning model for automated muscle segmentation on spin-echo and Dixon magnetic resonance imaging (MRI) for ...

Jun 27 2026 42362936
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