Pulmonology

Tuberculosis

Latest AI and machine learning research in tuberculosis for healthcare professionals.

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Beyond isolated cough events: AI-based tuberculosis screening through temporal analysis of cough sounds

Tuberculosis (TB) is a major global health challenge, with many cases remaining undiagnosed due to limited access to screening and diagnostic services. Artificial intelligence (AI) systems based on cough sound analysis offer a scalable and accessible approach to TB screening, but most previous studies have analysed isolated cough events, despite the possibility that diagnostically useful informati...

Monocyte-amplified transcriptional signatures of human diseases

Blood-based biomarkers discovered by machine learning often lack disease specificity and cross-population robustness for clinical applications. We describe a biomarker discovery strategy that exploits monocytes as circulating sentinels to amplify disease-perturbed signals in blood. This strategy leverages monocyteMINER, a mechanistic transcriptional regulatory network inferred from monocyte transc...

A large language model-assisted workflow for generating a living evidence base for climate-sensitive foodborne disease

Abstract Climate change is altering environmental conditions that influence foodborne disease transmission, yet traditional systematic reviews cannot ...

Improving Generalizability in Whole-Cell Antibiotic Discovery Through Active Learning

Machine learning (ML) has accelerated molecular discovery, yet training models to generalize to out-of-distribution (OOD) chemical spaces remains fund...

Benchmarking the translational potential of AI-based drug-resistance prediction from Mycobacterium tuberculosis whole-genome sequencing data

Background: Tuberculosis, especially drug-resistant tuberculosis (DR-TB) including multidrug-resistant (MDR) and extensively drug-resistant (XDR) stra...

Shared Pain, Shared Decisions: How Empathy Shapes Social Conformity Through Physiology and Visual Attention

Empathy enables individuals to attune to others' experiences through shared affective, sensorimotor, and neural representations, but its influence on ...

DDTRN: Predicting Bacterial Transcriptional Regulatory Networks Based on Gene Sequences using Dual Descriptor

Accurate computational reconstruction of bacterial transcriptional regulatory network (TRN) from sequence information alone remains a fundamental chal...

SAFE-DiT: Semantics-Aware Fast-path Execution for High-Resolution Diffusion Transformers

High-resolution Diffusion Transformer (DiT) inference contains substantial spatial redundancy, but many spatially adaptive implementations encode regi...

Jun 28 2026 2606.29360v1
A number simplex in the human medial temporal lobe

Humans handle numbers nimbly, suggesting a richer neural manifold structure than the prevalent mental number line model. In populations of medial temp...

KG-TRACE: A Neuro-Symbolic Framework for Mechanistic Grounding in Antimicrobial Resistance Prediction

While WGS-based AMR prediction has reached high accuracy, existing models lack a mechanism to ground neural attributions in established biological pat...

Jun 24 2026 2606.26179v1
Compositional and interpretable representation of histology using AI foundation models and sparse autoencoders

Light microscopy of tissue sections stained with hematoxylin and eosin (H&E) has been the foundation of histopathology for over 150 years and remains ...

NightSight: Passive Computation for Navigation in Dark Using Events

Small aerial robots are particularly well-suited for search and rescue in confined and hazardous environments due to their agility, low cost, and abil...

May 25 2026 2605.26330v1
Genomic Diagnostics for Drug-Resistant Mycobacterium tuberculosis: Computational Prediction of Antimicrobial Resistance

Tuberculosis remains a leading cause of infectious disease mortality, and the continued emergence of drug-resistant Mycobacterium tuberculosis strains...

Geographical targeting of active case finding for tuberculosis in Pakistan using artificial intelligence software (SPOT-TB): a pragmatic stepped wedge cluster randomized control trial.

Background Community-wide active case-finding (ACF) is being increasingly implemented as a tuberculosis (TB) elimination intervention. However, conven...

Learning Chirality-Aware Representations to Predict Drug Side Effect Frequencies

Ab initio prediction of side effect frequencies is important for assessing the risk-benefit profile of drugs and for identifying potential adverse eff...

Integration of immunomonitoring assays with PET/CT in TB patients identifies on-treatment biomarkers

Tuberculosis (TB) continues to pose a significant global public health challenge with substantial morbidity and mortality. Current TB biomarkers lack ...

Learned Lyapunov Shielding for Adaptive Control

We augment the Slotine--Li adaptive controller for Euler--Lagrange systems with three learned components: a structured-quadratic Lyapunov function \(V...

May 7 2026 2605.06934v1
Continuous Expert Assembly: Instance-Conditioned Low-Rank Residuals for All-in-One Image Restoration

Real-world image degradation is often unknown, spatially non-uniform, and compositional, requiring all-in-one restoration models to adapt a single set...

May 7 2026 2605.06127v1
Full-Field Stimulus Test for Visual Function Assessment in Ultra-Low Vision with Retinitis Pigmentosa

Purpose: Assessing visual function in patients with ultra-low vision (ULV), particularly those with retinitis pigmentosa (RP), remains a significant c...

DOT-Sim: Differentiable Optical Tactile Simulation with Precise Real-to-Sim Physical Calibration

Simulating optical tactile sensors presents significant challenges due to their high deformability and intricate optical properties. To address these ...

Apr 30 2026 2604.27367v1
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