Universal precautions

Classification models of HCV NS3 protease inhibitors based on support vector machine (SVM).

Inhibition of the hepatitis C virus (HCV) non-structural protein 3 (NS3) serine protease by molecule inhibitors is an attractive strategy for the treatment of hepatitis C. We built four classification models based on a dataset of 413 HCV NS3 protease inhibitors using support vector machine method. The best performing model obtains the best prediction performance for the test set with prediction ac...

On the Origins of Hepatitis C Virus NS5B Polymerase Inhibitory Activity Using Machine Learning Approaches.

Inhibition of non-structural protein 5B (NS5B) represents an attractive strategy for the therapeutic treatment of hepatitis C virus (HCV). In this study, machine learning classifiers such as artificial neural network (ANN), support vector machine (SVM), random forest (RF) and decision tree (DT) analyses were used to classify 970 compounds based on their physicochemical properties, including quantu...

Gist Representations and Communication of Risks about HIV-AIDS: A Fuzzy-Trace Theory Approach.

As predicted by fuzzy-trace theory, people with a range of training—from untrained adolescents to expert physicians—are susceptible to biases and erro...

Control of HIV/AIDS infection system with drug dosages design via robust H(∞) fuzzy controller.

The designing of H∞ fuzzy controller for HIV/AIDS infected dynamic system has been considered in this paper. With TS fuzzy model and LMIs approach, th...

CHARACTERISTICS OF HEPATITIS B VIRUS COINFECTION AMONG HIV-INFECTED PREGNANT WOMEN.

UNLABELLED: The similar routes of transmission for HIV and HBV place patients with either infection at greater risk for HIV/HBV co-infection.

[A case report of hepatitis B virus reactivation in a hepatitis B core antibody-positive, hepatitis B surface antigen-negative hemodialysis patient].

Reactivation of the hepatitis B virus (HBV) has been reported in patients receiving immunosuppressive therapy or chemotherapy. We report a case of HBV...

Establishment of hepatitis A vaccine (inactivated, non-adsorbed) BRP batches 2 and 3.

The current hepatitis A vaccine (HAV), inactivated, non-adsorbed, European Pharmacopoeia (Ph. Eur.) Biological Reference Preparation (BRP) is used for...

[Influence of magnetic field on the growth of pathogen microorganisms isolated from the indoor environment at the Archivo Nacional de la República de Cuba].

INTRODUCTION: Electromagnetic pollution has been detected at the Archivo Nacional de la República de Cuba and the influence of extremely low frequency...

Deep sequencing of HIV-1 variants from paired plasma and cerebrospinal fluid during primary HIV infection.

BACKGROUND: Limited data exist comparing viral quasispecies between cerebrospinal fluid (CSF) and plasma compartments during primary HIV infection. De...

[Surviving Forms in Antibiotic-Treated Pseudomonas aeruginosa].

Survival of bacterial populations treated with lethal doses of antibiotics is ensured by the presence of very small numbers of persister cells. Unlike...

[Maintenance therapy for chronic hepatitis C].

Therapy of chronic hepatitis C presently achieves 60% of sustained virological response, with clear on improvement of liver histology. Failure to erad...

[Retreatment strategies for the patients with HCV infection].

Despite recent advances in the treatment of chronic hepatitis C, especially introduction of combined therapy with pegylated interferons with ribavirin...

AIDS causes sharp rise in number of Brazilian orphans.

An estimated 183,000 Brazilian children are at risk of losing their mothers to AIDS, according to a survey released. The survey, sponsored by UNICEF, ...