Universal precautions

Taxonomy, biological characterization and fungicide sensitivity assays of Hypomyces cornea sp. nov. causing cobweb disease on Auricularia cornea.

Auricularia cornea is an important edible mushroom crop in China but the occurrence of cobweb disease has cause significance economic loss in its production. The rate of disease occurrence is 16.65% all over the country. In the present study, a new pathogen Hypomyces cornea sp. nov. was found to cause the cobweb disease. In July 2021, three strains of fungal pathogen were isolated from infected fr...

Serological and Molecular Characterization of Occult HBV Infection in Blood Donors from South Italy.

Despite good vaccine coverage and careful blood donor selection policies, hepatitis B virus (HBV) is still the most frequent viral infection among blood donors (BDs) in Italy, mostly in the occult form (OBI). We studied the virological features of OBI in BDs from South Italy by serology, molecular testing for HBV-DNA, and sequencing for HBV genotypes and mutations. One hundred and two samples from...

Influences of microRNA-451 on the expression of HMGB1 in myocardial cells and its mechanism in ischemia-reperfusion injury.

This work aimed to understand the underlying mechanism of micro-ribonucleic acid (MicroRNA) (miR)-451 in ischemia-reperfusion injury (IRI) and the inf...

Effect of dexamethasone and tenoxicam on the virulence activities of different clinical isolates.

INTRODUCTION: This study aimed to examine the effect of commonly used non-antibiotic drugs (dexamethasone and tenoxicam), on treatment of infections,...

Regulatory effects of mangiferin on LPS-induced inflammatory responses and intestinal flora imbalance during sepsis.

Studies suggest that mangiferin (MAF) has good therapeutic effects on chronic bronchitis and hepatitis. Also, it is one of the antiviral ingredients i...

Investigating the bispecific lead compounds against methicillin-resistant SarA and CrtM using machine learning and molecular dynamics approach.

Methicillin-resistant Staphylococcus aureus (MRSA) is a notorious pathogen that has emerged as a serious global health concern over the past few decad...

Virological Findings and Treatment Outcomes of Cases That Developed Dolutegravir Resistance in Malawi's National HIV Treatment Program.

Millions of Africans are on dolutegravir-based antiretroviral therapy (ART), but few detailed descriptions of dolutegravir resistance and its clinical...

Investigating Novel IspE Inhibitors of the MEP Pathway in Mycobacterium.

In a recent effort to mitigate harm from human pathogens, many biosynthetic pathways have been extensively evaluated for their ability to inhibit path...

Methicillin-Resistant (MRSA) in a Tertiary Care Hospital in Kuwait: A Molecular and Genetic Analysis.

Methicillin-resistant (MRSA) is a major pathogen that causes serious infections in healthcare facilities and in communities. The purpose of this stud...

Deep Learning Model for Classifying and Evaluating Soybean Leaf Disease Damage.

Soybean ( (L.) Merr.) is a major source of oil and protein for human food and animal feed; however, soybean crops face diverse factors causing damage,...

Machine learning and experimental screening of chromatin regulator signatures and potential drugs in hepatitis B related hepatocellular carcinoma.

Many evidences have confirmed that chromatin regulator factors (CRs) are involved in the progression of cancer, but its potential mechanism of affecti...

Deployment and assessment of a deep learning model for real-time detection of anal precancer with high frame rate high-resolution microendoscopy.

Anal cancer incidence is significantly higher in people living with HIV as HIV increases the oncogenic potential of human papillomavirus. The incidenc...

Efficiency of face mask ventilation before and after neuromuscular blockade: A randomised, double-blind controlled study.

BACKGROUND AND AIMS: The traditional practice of administrating neuromuscular blocking drugs (NMBDs) after checking face mask ventilation is challenge...

Screening and Identification of DNA Nanostructure Aptamer Using the SELEX Method for ‎Detection of Epsilon Toxin.

BACKGROUND: Epsilon toxin (ETX), produced by , is one of the most potent toxins known, with a lethal potency approaching that of botulinum neurotoxins...

Detection of the separated endodontic instrument on periapical radiographs using a deep learning-based convolutional neural network algorithm.

The study evaluated the diagnostic performance of an artificial intelligence system to detect separated endodontic instruments on periapical radiograp...

Computational drug discovery on human immunodeficiency virus with a customized long short-term memory variational autoencoder deep-learning architecture.

Despite attempts to control the spread of human immunodeficiency virus (HIV) through the use of anti-HIV medications, the absence of an effective vacc...

Validation of a Bacteriophage Hide Application to Reduce STEC in the Lairage Area of Commercial Beef Cattle Operations.

Finalyse, a T4 bacteriophage, is a pre-harvest intervention that utilizes a combination of bacteriophages to reduce incoming O157:H7 prevalence by de...

The application of artificial intelligence in the management of sepsis.

Sepsis is a complex and heterogeneous syndrome that remains a serious challenge to healthcare worldwide. Patients afflicted by severe sepsis or septic...

Waterborne pathogens detection technologies: advances, challenges, and future perspectives.

The World Health Organization (WHO) estimated that pathogens like Escherichia coli, primarily linked to food and water contamination, are associated w...

Characterization of a -targeting lytic bacteriophage SSJ01 and its application in artificial seawater.

is a major foodborne pathogen causing serious illnesses. In this study, a new lytic bacteriophage SSJ01 that infects was isolated and characterized....