Universal precautions

Ritonavir-boosted paritaprevir, ombitasvir plus ribavirin could improve eGFR in patients with renal impairment and HCV: an Egyptian cohort.

BACKGROUND: The present study aimed at evaluation of changes in estimated glomerular filtration rate (eGFR) among chronic Hepatitis C virus (HCV) patients with chronic kidney disease (CKD) Stages 3-5 who were treated with 12 weeks of ritonavir-boosted paritaprevir, ombitasvir plus ribavirin.

Systems Biology and Machine Learning in Plant-Pathogen Interactions.

Systems biology is an inclusive approach to study the static and dynamic emergent properties on a global scale by integrating multiomics datasets to establish qualitative and quantitative associations among multiple biological components. With an abundance of improved high throughput -omics datasets, network-based analyses and machine learning technologies are playing a pivotal role in comprehensi...

Accurate prediction of blood culture outcome in the intensive care unit using long short-term memory neural networks.

INTRODUCTION: Blood cultures are often performed in the intensive care unit (ICU) to detect bloodstream infections and identify pathogen type, further...

Gene Essentiality Analyzed by Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of .

Knowing the full set of essential genes for a given organism provides important information about ways to promote, and to limit, its growth and surviv...

Pathogen Identification Direct From Polymicrobial Specimens Using Membrane Glycolipids.

With the increased prevalence of multidrug-resistant Gram-negative bacteria, the use of colistin and other last-line antimicrobials is being revisited...

Orthotopic Liver Transplantation After Stereotactic Body Radiotherapy for Pediatric Hepatocellular Carcinoma with Central Biliary Obstruction and Nodal Involvement.

Here we describe the case of a 10-year-old boy with a history of chronic hepatitis B who was diagnosed with hepatocellular carcinoma (HCC) with a larg...

Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance.

Mycobacterium tuberculosis is a serious human pathogen threat exhibiting complex evolution of antimicrobial resistance (AMR). Accordingly, the many pu...

[Hepatitis B and renal failure: prevalence and associated factors in National University Hospital Center of Cotonou].

INTRODUCTION: the association between the kidneys and hepatitis B is complex. This study aims to determine the prevalence and factors associated with ...

[An unusual cause of jaundice].

Hepatic impairment is common during hyperthyroidism. It is most often asymptomatic. Hyperthyroidism revealed by jaundice has been rarely described in ...

A nano-carrier platform for the targeted delivery of nature-inspired antimicrobials using Engineered Water Nanostructures for food safety applications.

Despite the progress in the area of food safety, foodborne diseases still represent a massive challenge to the public health systems worldwide, mainly...

Relative Adrenal Insufficiency in Patients with Alcoholic Hepatitis.

BACKGROUND/AIMS: Alcoholic hepatitis (AH) is an acute hepatic inflammation associated with high morbidity and mortality. Treatment with steroids is kn...

A comparative study of logistic regression based machine learning techniques for prediction of early virological suppression in antiretroviral initiating HIV patients.

BACKGROUND: Treatment with effective antiretroviral therapy (ART) lowers morbidity and mortality among HIV positive individuals. Effective highly acti...

Hierarchical Convolutional Neural Networks for Segmentation of Breast Tumors in MRI With Application to Radiogenomics.

Breast tumor segmentation based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a challenging problem and an active area of resea...

Designing robot-assisted neurorehabilitation strategies for people with both HIV and stroke.

There is increasing evidence that HIV is an independent risk factor for stroke, resulting in an emerging population of people living with both HIV and...

Clinical prediction of HBV and HCV related hepatic fibrosis using machine learning.

Clinical prediction of advanced hepatic fibrosis (HF) and cirrhosis has long been challenging due to the gold standard, liver biopsy, being an invasiv...

Label-Free Biomolecule Detection in Physiological Solutions With Enhanced Sensitivity Using Graphene Nanogrids FET Biosensor.

Recently, graphene nanogrid sensor has been reported to be capable of sub-femtomolar sensing of Hepatitis B (Hep-B) surface antigen in buffer. However...

Robotic selection for the rapid development of stable CHO cell lines for HIV vaccine production.

The production of envelope glycoproteins (Envs) for use as HIV vaccines is challenging. The yield of Envs expressed in stable Chinese Hamster Ovary (C...

Predicting Infectious Disease Using Deep Learning and Big Data.

Infectious disease occurs when a person is infected by a pathogen from another person or an animal. It is a problem that causes harm at both individua...

A Machine Learning Approach for Predicting HIV Reverse Transcriptase Mutation Susceptibility of Biologically Active Compounds.

HIV resistance emerging against antiretroviral drugs represents a great threat to the continued prolongation of the lifespans of HIV-infected patients...

Molecular Genotyping of Species Isolated from Patients in Tehran, Iran, by Repetitive Element PCR Fingerprinting.

BACKGROUND & OBJECTIVE: is an opportunistic pathogen with high pathogenic and antibiotic-resistance potential and is also considered as one of the ma...