Urology

General practitioner perception of prostate-specific antigen testing has improved, but more awareness of prostate cancer risk in younger patients is still awaited.

BACKGROUND: In 2006, a county-wide survey of general practitioners (GPs) in the United Kingdom (UK) identified a reluctance to refer younger men with abnormal prostate specific antigen (PSA) levels. Younger men have the most to gain from early-detection of prostate cancer (PCa), which remains a national government priority in the UK and around the world. We sought to assess changes in perception o...

Sub-acute administration of lower doses of nicotine caused sex-dependent improvement of renal function in Wistar rats.

The adverse and beneficial health effects of nicotine (NIC), the major alkaloid found in cigarettes and tobacco, are controversial. Most studies on NIC have focused on its effects on cardiovascular and nervous functions. This study aimed at determining dose- and sex-specific effects of sub-acute (28 days) NIC administration on some indices of kidney function in Wistar rats. Forty rats (20 males an...

Associations of ambient coarse particulate matter, nitrogen dioxide, and carbon monoxide with the risk of kidney disease: a cohort study.

BACKGROUND: Experimental evidence and preliminary clinical evidence suggest that environmental air pollution adversely effects kidney health. Previous...

Identification of potentially oncogenic alterations from tumor-only samples reveals Fanconi anemia pathway mutations in bladder carcinomas.

Cancer is caused by germline and somatic mutations, which can share biological features such as amino acid change. However, integrated germline and so...

Re: Robot-assisted Salvage Lymph Node Dissection for Clinically Recurrent Prostate Cancer.

Pharmacokinetics, bioavailability, tissue distribution and excretion of tangeretin in rat.

Tangeretin, 4',5,6,7,8-pentamethoxyflavone, is one of the major polymethoxyflavones (PMFs) existing in citrus fruits, particularly in the peels of swe...

A combined learning algorithm for prostate segmentation on 3D CT images.

PURPOSE: Segmentation of the prostate on CT images has many applications in the diagnosis and treatment of prostate cancer. Because of the low soft-ti...

Re: Neurovascular Bundle Size Measured on 3.0-T Magnetic Resonance Imaging is Associated with the Recovery of Erectile Function after Robot-Assisted Radical Prostatectomy.

Survivability prediction of colon cancer patients using neural networks.

We utilize deep neural networks to develop prediction models for patient survival and conditional survival of colon cancer. Our models are trained and...

Validation of a Machine Learning Approach for Venous Thromboembolism Risk Prediction in Oncology.

Using kernel machine learning (ML) and random optimization (RO) techniques, we recently developed a set of venous thromboembolism (VTE) risk predictor...

Development of a Natural Language Processing Engine to Generate Bladder Cancer Pathology Data for Health Services Research.

OBJECTIVE: To take the first step toward assembling population-based cohorts of patients with bladder cancer with longitudinal pathology data, we deve...

[Evaluation of equations using cystatin C for estimation of the glomerular filtration rate in healthy adult population of canidates for kidney donors.].

The determination of the glomerular filtration rate (GFR) is critical for the selection of potential kidney donors. Methods of measurement of GFR are ...

Natural History and Predictors of Parastomal Hernia after Robot-Assisted Radical Cystectomy and Ileal Conduit Urinary Diversion.

PURPOSE: We investigated the prevalence of and variables associated with parastomal hernia and its outcomes after robot-assisted radical cystectomy an...

Urinary bladder cancer staging in CT urography using machine learning.

PURPOSE: To evaluate the feasibility of using an objective computer-aided system to assess bladder cancer stage in CT Urography (CTU).

Influence of Referral to a Combined Diabetology and Nephrology Clinic on Renal Functional Trends and Metabolic Parameters in Adults With Diabetic Kidney Disease.

OBJECTIVE: To examine the impact of a diabetes renal clinic (DRC) on renal functional and metabolic indices in adults who have diabetes mellitus (DM) ...

Interstitial inflammation and interstitial fibrosis and tubular atrophy predict renal survival in lupus nephritis.

BACKGROUND: This study examines the effect of interstitial inflammation and interstitial fibrosis and tubular atrophy on renal survival in lupus nephr...

DRMDA: deep representations-based miRNA-disease association prediction.

Recently, microRNAs (miRNAs) are confirmed to be important molecules within many crucial biological processes and therefore related to various complex...

Re: Robot-assisted Laparoscopic Prostatectomy Versus Open Radical Retropubic Prostatectomy: Early Outcomes from a Randomised Controlled Phase 3 Study.

A Machine Learning Approach Using Survival Statistics to Predict Graft Survival in Kidney Transplant Recipients: A Multicenter Cohort Study.

Accurate prediction of graft survival after kidney transplant is limited by the complexity and heterogeneity of risk factors influencing allograft sur...

Bladder Cancer Treatment Response Assessment in CT using Radiomics with Deep-Learning.

Cross-sectional X-ray imaging has become the standard for staging most solid organ malignancies. However, for some malignancies such as urinary bladde...