Urology

Latest AI and machine learning research in urology for healthcare professionals.

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Can metformin prevent cancer relative to sulfonylureas? A target trial emulation accounting for competing risks and poor overlap via double/debiased machine learning estimators.

There is mounting interest in the possibility that metformin, indicated for glycemic control in type 2 diabetes, has a range of additional beneficial effects. Randomized trials have shown that metformin prevents adverse cardiovascular events, and metformin use has also been associated with reduced cognitive decline and cancer incidence. In this paper, we dig more deeply into whether metformin prev...

Feb 5 2025 39030720

Adaptive Voxel-Weighted Loss Using L1 Norms in Deep Neural Networks for Detection and Segmentation of Prostate Cancer Lesions in PET/CT Images

This study proposes a new loss function for deep neural networks, L1-weighted Dice Focal Loss (L1DFL), that leverages L1 norms for adaptive weighting of voxels based on their classification difficulty, towards automated detection and segmentation of metastatic prostate cancer lesions in PET/CT scans. We obtained 380 PSMA [18-F] DCFPyL PET/CT scans of patients diagnosed with biochemical recurrenc...

AAD-DCE: An Aggregated Multimodal Attention Mechanism for Early and Late Dynamic Contrast Enhanced Prostate MRI Synthesis

Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) is a medical imaging technique that plays a crucial role in the detailed visualizatio...

Can Domain Experts Rely on AI Appropriately? A Case Study on AI-Assisted Prostate Cancer MRI Diagnosis

Despite the growing interest in human-AI decision making, experimental studies with domain experts remain rare, largely due to the complexity of wor...

Registration-Enhanced Segmentation Method for Prostate Cancer in Ultrasound Images

Prostate cancer is a major cause of cancer-related deaths in men, where early detection greatly improves survival rates. Although MRI-TRUS fusion bi...

Prostate-Specific Foundation Models for Enhanced Detection of Clinically Significant Cancer

Accurate prostate cancer diagnosis remains challenging. Even when using MRI, radiologists exhibit low specificity and significant inter-observer var...

Actor Critic with Experience Replay-based automatic treatment planning for prostate cancer intensity modulated radiotherapy

Background: Real-time treatment planning in IMRT is challenging due to complex beam interactions. AI has improved automation, but existing models re...

Application of artificial intelligence and machine learning for risk stratification acute kidney injury among hematopoietic stem cell transplantation patients: PCRRT ICONIC AI Initiative Group Meeting Proceedings.

Acute kidney injury (AKI) is a frequent, severe complication of hematopoietic stem cell transplantation (HSCT) and is associated with an increased ris...

Feb 1 2025 39545392
Deep learning-based classifier for carcinoma of unknown primary using methylation quantitative trait loci.

Cancer of unknown primary (CUP) constitutes between 2% and 5% of human malignancies and is among the most common causes of cancer death in the United ...

Feb 1 2025 39607989
Machine Learning Accurately Predicts Muscle Invasion of Bladder Cancer Based on Three miRNAs.

The aim of this study was to validate the diagnostic potential of four previously identified miRNAs in two independent cohorts and to develop accurate...

Feb 1 2025 39929768
Prediction of Prostate Cancer Grades Using Radiomic Features.

We developed a machine learning model for predicting prostate cancer (PCa) grades using radiomic features of magnetic resonance imaging. 112 patients ...

Feb 1 2025 40012156
Current applications and future perspectives of artificial intelligence in functional urology and neurourology: how far can we get?

In the last few years, the scientific community has seen an increasing interest towards the potential applications of artificial intelligence in medic...

Feb 1 2025 40183181
Multimodal MRI-Ultrasound AI for Prostate Cancer Detection Outperforms Radiologist MRI Interpretation: A Multi-Center Study

Pre-biopsy magnetic resonance imaging (MRI) is increasingly used to target suspicious prostate lesions. This has led to artificial intelligence (AI)...

Influence of High-Performance Image-to-Image Translation Networks on Clinical Visual Assessment and Outcome Prediction: Utilizing Ultrasound to MRI Translation in Prostate Cancer

Purpose: This study examines the core traits of image-to-image translation (I2I) networks, focusing on their effectiveness and adaptability in every...

Aggregation Schemes for Single-Vector WSI Representation Learning in Digital Pathology

A crucial step to efficiently integrate Whole Slide Images (WSIs) in computational pathology is assigning a single high-quality feature vector, i.e....

Multi-Objective Deep-Learning-based Biomechanical Deformable Image Registration with MOREA

When choosing a deformable image registration (DIR) approach for images with large deformations and content mismatch, the realism of found transform...

Efficient Self-Supervised Grading of Prostate Cancer Pathology

Prostate cancer grading using the ISUP system (International Society of Urological Pathology) for treatment decisions is highly subjective and requi...

AI in Oncology: Transforming Cancer Detection through Machine Learning and Deep Learning Applications

Artificial intelligence (AI) has potential to revolutionize the field of oncology by enhancing the precision of cancer diagnosis, optimizing treatme...

Development and Validation of a Dynamic Kidney Failure Prediction Model based on Deep Learning: A Real-World Study with External Validation

Background: Chronic kidney disease (CKD), a progressive disease with high morbidity and mortality, has become a significant global public health pro...

Cinepro: Robust Training of Foundation Models for Cancer Detection in Prostate Ultrasound Cineloops

Prostate cancer (PCa) detection using deep learning (DL) models has shown potential for enhancing real-time guidance during biopsies. However, prost...

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