Infectious Disease

Vaccines

Latest AI and machine learning research in vaccines for healthcare professionals.

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Showing 21-40 of 7,951 articles

iHaptenAb: an integrated hapten-antibody database for rational hapten design and antibody discovery.

Antibodies targeting small molecules play indispensable roles in food safety, environmental monitoring, clinical diagnostics, and immunotherapy. The generation of such antibodies critically depends on hapten design. Although several generic antibody databases exist, an open resource that specifically integrates haptens and the corresponding antibody performance has remained unavailable, thereby li...

Aug 13 2026 42590899

Somalia's lifeline: Digitalization and AI.

Somalia's fragile health system, strained by decades of conflict, climate shocks, and persistently low immunization coverage, remains dangerously vulnerable to preventable disease outbreaks. With measles resurgent and full vaccination coverage stagnating at just 55% nationally and as low as 26% in some states - the country faces recurrent epidemics it cannot withstand. Digitalization and artificia...

Aug 12 2026 42583880
Mechanistic machine learning for prediction of prime editing outcomes.

Prime editing (PE) can make specific local changes to genomic DNA in living systems but its efficient application currently requires extensive optimiz...

Aug 12 2026 42587136
Real-world analysis of depression-related adverse events associated with the adsorbed anthrax vaccine: integrating pharmacovigilance signals, machine learning risk prediction, and transcriptomic mechanisms.

BACKGROUND: Anthrax remains a life-threatening zoonotic disease in resource-limited settings. Adsorbed anthrax vaccine (AVA, BioThrax) is the only Uni...

Aug 10 2026 42576235
Optimising Pharmacovigilance Efficiency with MLIT (Machine Learning for Intelligent Triage): A Tool for Statistical Safety Alerts.

BACKGROUND AND AIM: Pharmacovigilance is essential to ensuring patient safety by enabling timely identification of adverse reactions in increasingly c...

Aug 10 2026 42573921
Beyond Accuracy: A Mixed-Methods Audit of Chain-of-Thought Failures in LLM-Based COVID-19 Vaccine Stance Detection.

This mixed-methods study assessed whether reasoning-enabled large language models (LLMs) can classify stances towards COVID-19 vaccination on X (forme...

Aug 8 2026 42570145
Modelling the impact of awareness campaigns on HPV transmission dynamics: a neural network-enhanced mathematical model.

HPV is the most common sexually transmitted infection; most sexually active individuals are exposed to HPV at some point in their lives, and the major...

Aug 6 2026 42557263
Theranostic innovation in infectious lung diseases: integrating biotechnology and nanotechnology for precision medicine.

INTRODUCTION: Introduction: Infectious lung diseases, including pneumonia, tuberculosis (TB), COVID-19, influenza, and emerging fungal infections, are...

Aug 4 2026 42549821
Explainable Machine Learning for Public Health Informatics in HEDIS Childhood Immunization Status Combination 10.

Completion of the HEDIS (Healthcare Effectiveness Data and Information Set) Childhood Immunization Status Combination 10 (Combo 10) measure among US c...

Jul 31 2026 42536080
Neonatal Bloodstream Infections: A Narrative Review on Diagnostic and Therapeutic Challenges and Prospects in Developing Countries.

BACKGROUND: Bloodstream infections (BSIs) pose a significant global health challenge, particularly in developing countries. Neonates are highly vulner...

Jul 29 2026 42534399
From fragmented records to living evidence: health system-governed, artificial intelligence-driven, continuously updated real-world clinical data from Truveta.

OBJECTIVES: Real-world data (RWD) have historically suffered from fragmentation, delayed availability, variable data quality, and limited analytic uti...

Jul 29 2026 42529767
Improving laboratory workforce efficiency using AI-assisted digital cytology within an HPV-based cervical screening programme: A model-based evaluation for the NHS Cervical Screening Programmes.

OBJECTIVES: We aimed to estimate the time required to review and report cervical cytology slides within a Human Papillomavirus (HPV)-primary cervical ...

Jul 28 2026 42526933
ViralMap: predicting features in viral proteins from primary sequence.

Modern viral vaccines are designed to elicit an immune response against viral proteins that mediate infection, making those proteins important targets...

Jul 28 2026 42517630
AI-Assisted Risk Stratification in Stage II Colorectal Cancer: Multi-Institutional Validation of Semantically-Enhanced Deep Learning.

BACKGROUND AND AIMS: Accurate risk stratification in stage II colorectal cancer is essential for treatment decision-making, as current guidelines reco...

Jul 28 2026 42521098
Combined Analysis of scRNA-seq and Bulk RNA-seq Sequencing Revealing the Heterogeneity of Recurrent Respiratory Papillomatosis and Key Molecular Mechanisms of Its Occurrence and Development.

OBJECTIVE: Recurrent respiratory papillomatosis (RRP) is a benign tumor that is highly prone to recurrence and has the potential to become malignant, ...

Jul 28 2026 42509150
The Role of Pharmacists in Tackling Mpox: Challenges and Future Prospects: A Narrative Review.

BACKGROUND AND AIMS: Pharmacists play a key role in managing and mitigating mpox through clinical care, pharmacovigilance, vaccine management, and res...

Jul 27 2026 42517023
Evaluating the Intermediate Suspicion Category in Thyroid Nodules with AI Assistance: A Comparative Analysis of C-TIRADS, ACR-TIRADS, and ATA Guidelines.

OBJECTIVE: To compare diagnostic performance and fine-needle aspiration (FNA) decision-making for thyroid nodules classified as "Intermediate Suspicio...

Jul 24 2026 42498197
Integrative single-cell and machine learning analysis identifies a tumor doubling time-related prognostic signature and therapeutic targets in head and neck squamous cell carcinoma.

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) exhibits marked molecular heterogeneity and diverse clinical outcomes, partly influenced by ...

Jul 23 2026 42492364
Personalized cancer vaccines: bridging immune-oncology and precision medicine for advanced therapeutics.

Despite advancements in therapeutic cancer vaccines, clinical translation has been hindered by limited efficacy, with Sipuleucel-T remaining the only ...

Jul 22 2026 42481451
Evolution of swine influenza surveillance and one health governance in Taiwan: from zoonotic risk management to integrated preparedness.

Influenza A viruses (IAVs) remain a persistent global threat because of rapid antigenic change, frequent genetic reassortment, and cross-species trans...

Jul 22 2026 42484785
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