Vaccines

Machine learning models to identify low adherence to influenza vaccination among Korean adults with cardiovascular disease.

BACKGROUND: Annual influenza vaccination is an important public health measure to prevent influenza infections and is strongly recommended for cardiovascular disease (CVD) patients, especially in the current coronavirus disease 2019 (COVID-19) pandemic. The aim of this study is to develop a machine learning model to identify Korean adult CVD patients with low adherence to influenza vaccination MET...

Towards in silico Process Modeling for Vaccines.

Chemical, manufacturing, and control development timelines occupy a significant part of vaccine end-to-end development. In the on-going race for accelerating timelines, in silico process development constitutes a viable strategy that can be achieved through an artificial intelligence (AI)-driven or a mechanistically oriented approach. In this opinion, we focus on the mechanistic option and report ...

DeepVISP: Deep Learning for Virus Site Integration Prediction and Motif Discovery.

Approximately 15% of human cancers are estimated to be attributed to viruses. Virus sequences can be integrated into the host genome, leading to genom...

A Comprehensive Overview of the COVID-19 Literature: Machine Learning-Based Bibliometric Analysis.

BACKGROUND: Shortly after the emergence of COVID-19, researchers rapidly mobilized to study numerous aspects of the disease such as its evolution, cli...

COVID-19 in early 2021: current status and looking forward.

Since the first description of a coronavirus-related pneumonia outbreak in December 2019, the virus SARS-CoV-2 that causes the infection/disease (COVI...

Individualized prediction of COVID-19 adverse outcomes with MLHO.

The COVID-19 pandemic has devastated the world with health and economic wreckage. Precise estimates of adverse outcomes from COVID-19 could have led t...

Generation of Dual functional Nanobody-Nanoluciferase Fusion and its potential in Bioluminescence Enzyme Immunoassay for trace Glypican-3 in Serum.

Glypican-3 (GPC3) is a serological biomarker for the diagnosis of Hepatocellular carcinoma (HCC), but it is a challenging task to develop a bioassay f...

Monitoring social distancing under various low light conditions with deep learning and a single motionless time of flight camera.

The purpose of this work is to provide an effective social distance monitoring solution in low light environments in a pandemic situation. The raging ...

Utilizing Computational Machine Learning Tools to Understand Immunogenic Breadth in the Context of a CD8 T-Cell Mediated HIV Response.

Predictive models are becoming more and more commonplace as tools for candidate antigen discovery to meet the challenges of enabling epitope mapping o...

From predictions to prescriptions: A data-driven response to COVID-19.

The COVID-19 pandemic has created unprecedented challenges worldwide. Strained healthcare providers make difficult decisions on patient triage, treatm...

An in silico deep learning approach to multi-epitope vaccine design: a SARS-CoV-2 case study.

The rampant spread of COVID-19, an infectious disease caused by SARS-CoV-2, all over the world has led to over millions of deaths, and devastated the ...

Predicting Potential SARS-COV-2 Drugs-In Depth Drug Database Screening Using Deep Neural Network Framework SSnet, Classical Virtual Screening and Docking.

Severe Acute Respiratory Syndrome Corona Virus 2 has altered life on a global scale. A concerted effort from research labs around the world resulted i...

Six artificial intelligence paradigms for tissue characterisation and classification of non-COVID-19 pneumonia against COVID-19 pneumonia in computed tomography lungs.

BACKGROUND: COVID-19 pandemic has currently no vaccines. Thus, the only feasible solution for prevention relies on the detection of COVID-19-positive ...

Diagnosis of COVID-19 using CT scan images and deep learning techniques.

Early diagnosis of the coronavirus disease in 2019 (COVID-19) is essential for controlling this pandemic. COVID-19 has been spreading rapidly all over...

Human papilloma virus detection in oropharyngeal carcinomas with in situ hybridisation using hand crafted morphological features and deep central attention residual networks.

Human Papilloma Virus (HPV) is a major risk factor for the development of oropharyngeal cancer. Automatic detection of HPV in digitized pathology tiss...

Use of machine learning to identify a T cell response to SARS-CoV-2.

The identification of SARS-CoV-2-specific T cell receptor (TCR) sequences is critical for understanding T cell responses to SARS-CoV-2. Accordingly, w...

A Novel Protein Mapping Method for Predicting the Protein Interactions in COVID-19 Disease by Deep Learning.

The new type of corona virus (SARS-COV-2) emerging in Wuhan, China has spread rapidly to the world and has become a pandemic. In addition to having a ...

Application of Artificial Intelligence to Address Issues Related to the COVID-19 Virus.

Artificial intelligence (AI) plays a major role in addressing novel coronavirus 2019 (COVID-19)-related issues and is also used in computer-aided synt...

Artificial Intelligence Model of Drive-Through Vaccination Simulation.

Planning for mass vaccination against SARS-Cov-2 is ongoing in many countries considering that vaccine will be available for the general public in the...

Design of novel orotransmucosal vaccine-delivery platforms using artificial intelligence.

The linings of the oral cavity are excellent needle-free vaccination sites, able to induce immune responses at distal sites and confer systemic protec...