AI Medical Compendium Journal:
American journal of epidemiology

Showing 1 to 10 of 24 articles

Challenges in Obtaining Valid Causal Effect Estimates with Machine Learning Algorithms.

American journal of epidemiology
Unlike parametric regression, machine learning (ML) methods do not generally require precise knowledge of the true data generating mechanisms. As such, numerous authors have advocated for ML methods to estimate causal effects. Unfortunately, ML algor...

Targeted Maximum Likelihood Estimation for Causal Inference in Observational Studies.

American journal of epidemiology
Estimation of causal effects using observational data continues to grow in popularity in the epidemiologic literature. While many applications of causal effect estimation use propensity score methods or G-computation, targeted maximum likelihood esti...

Improving propensity score estimators' robustness to model misspecification using super learner.

American journal of epidemiology
The consistency of propensity score (PS) estimators relies on correct specification of the PS model. The PS is frequently estimated using main-effects logistic regression. However, the underlying model assumptions may not hold. Machine learning metho...

Automated identification of fall-related injuries in unstructured clinical notes.

American journal of epidemiology
Fall-related injuries (FRIs) are a major cause of hospitalizations among older patients, but identifying them in unstructured clinical notes poses challenges for large-scale research. In this study, we developed and evaluated natural language process...

Can metformin prevent cancer relative to sulfonylureas? A target trial emulation accounting for competing risks and poor overlap via double/debiased machine learning estimators.

American journal of epidemiology
There is mounting interest in the possibility that metformin, indicated for glycemic control in type 2 diabetes, has a range of additional beneficial effects. Randomized trials have shown that metformin prevents adverse cardiovascular events, and met...

Invited commentary: deep learning-methods to amplify epidemiologic data collection and analyses.

American journal of epidemiology
Deep learning is a subfield of artificial intelligence and machine learning, based mostly on neural networks and often combined with attention algorithms, that has been used to detect and identify objects in text, audio, images, and video. Serghiou a...

A causal machine-learning framework for studying policy impact on air pollution: a case study in COVID-19 lockdowns.

American journal of epidemiology
When studying the impact of policy interventions or natural experiments on air pollution, such as new environmental policies or the opening or closing of an industrial facility, careful statistical analysis is needed to separate causal changes from o...

Machine learning for detection of heterogeneous effects of Medicaid coverage on depression.

American journal of epidemiology
In 2008, Oregon expanded its Medicaid program using a lottery, creating a rare opportunity to study the effects of Medicaid coverage using a randomized controlled design (Oregon Health Insurance Experiment). Analysis showed that Medicaid coverage low...

Harnessing causal forests for epidemiologic research: key considerations.

American journal of epidemiology
Assessing heterogeneous treatment effects (HTEs) is an essential task in epidemiology. The recent integration of machine learning into causal inference has provided a new, flexible tool for evaluating complex HTEs: causal forest. In a recent paper, J...

Deep Learning for Epidemiologists: An Introduction to Neural Networks.

American journal of epidemiology
Deep learning methods are increasingly being applied to problems in medicine and health care. However, few epidemiologists have received formal training in these methods. To bridge this gap, this article introduces the fundamentals of deep learning f...