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Sulfonylurea Compounds

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Early detection of nicosulfuron toxicity and physiological prediction in maize using multi-branch deep learning models and hyperspectral imaging.

Journal of hazardous materials
The misuse of herbicides in fields can cause severe toxicity in maize, resulting in significant reductions in both yield and quality. Therefore, it is crucial to develop early and efficient methods for assessing herbicide toxicity, protecting maize p...

A green and efficient method for detecting nicosulfuron residues in field maize using hyperspectral imaging and deep learning.

Journal of hazardous materials
Accurate and rapid detection of nicosulfuron herbicide residues in field-grown maize is essential for implementing chemical remediation and optimizing spraying strategies. However, current detection methods are costly and time-consuming. This study a...

SERPINA3: A Novel Therapeutic Target for Diabetes-Related Cognitive Impairment Identified Through Integrated Machine Learning and Molecular Docking Analysis.

International journal of molecular sciences
Diabetes-related cognitive impairment (DCI) is a severe complication of type 2 diabetes mellitus (T2DM), with limited understanding of its molecular mechanisms hindering effective therapeutic development. This study identified SERPINA3 as a potential...

Can metformin prevent cancer relative to sulfonylureas? A target trial emulation accounting for competing risks and poor overlap via double/debiased machine learning estimators.

American journal of epidemiology
There is mounting interest in the possibility that metformin, indicated for glycemic control in type 2 diabetes, has a range of additional beneficial effects. Randomized trials have shown that metformin prevents adverse cardiovascular events, and met...