AI Medical Compendium Journal:
Journal of biomedical informatics

Showing 1 to 10 of 650 articles

Knowledge-enhanced Parameter-efficient Transfer Learning with METER for medical vision-language tasks.

Journal of biomedical informatics
OBJECTIVE: The full fine-tuning paradigm becomes impractical when applying pre-trained models to downstream tasks due to significant computational and storage costs. Parameter-efficient fine-tuning (PEFT) methods can alleviate the issue. However, sol...

Multimodal fusion architectures for Alzheimer's disease diagnosis: An experimental study.

Journal of biomedical informatics
OBJECTIVE: In the attempt of early diagnosis of Alzheimer's Disease, varying forms of medical records of multiple modalities are gathered to seize the interaction of multiple factors. However, the heterogeneity of multimodal data brings a challenge. ...

A transformer-based framework for temporal health event prediction with graph-enhanced representations.

Journal of biomedical informatics
OBJECTIVE: Deep learning approaches have demonstrated significant potential in predicting temporal health events in recent years. However, existing methods have not fully leveraged the complex interactions among comorbidities and have overlooked imba...

PregAN-NET: Addressing Class Imbalance with GANs in Interpretable Computational Framework for Predicting Safety Profile of Drugs Considering Adverse Reactions During Pregnancy.

Journal of biomedical informatics
Adverse Drug Reactions (ADRs) during pregnancy pose significant risks to both the mother and the fetus. Conventional approaches to predict ADR are inadequate due to ethical restrictions that prevent performing medication studies in pregnant women, le...

Unsupervised discovery of clinical disease signatures using probabilistic independence.

Journal of biomedical informatics
OBJECTIVE: This study uses probabilistic independence to disentangle patient-specific sources of disease and their signatures in Electronic Health Record (EHR) data.

Leveraging natural language processing to elucidate real-world clinical decision-making paradigms: A proof of concept study.

Journal of biomedical informatics
BACKGROUND: Understanding how clinicians arrive at decisions in actual practice settings is vital for advancing personalized, evidence-based care. However, systematic analysis of qualitative decision data poses challenges.

ICPPNet: A semantic segmentation network model based on inter-class positional prior for scoliosis reconstruction in ultrasound images.

Journal of biomedical informatics
OBJECTIVE: Considering the radiation hazard of X-ray, safer, more convenient and cost-effective ultrasound methods are gradually becoming new diagnostic approaches for scoliosis. For ultrasound images of spine regions, it is challenging to accurately...

RoBIn: A Transformer-based model for risk of bias inference with machine reading comprehension.

Journal of biomedical informatics
OBJECTIVE: Scientific publications are essential for uncovering insights, testing new drugs, and informing healthcare policies. Evaluating the quality of these publications often involves assessing their Risk of Bias (RoB), a task traditionally perfo...

Benchmarking domain-specific pretrained language models to identify the best model for methodological rigor in clinical studies.

Journal of biomedical informatics
OBJECTIVE: Encoder-only transformer-based language models have shown promise in automating critical appraisal of clinical literature. However, a comprehensive evaluation of the models for classifying the methodological rigor of randomized controlled ...

A novel machine learning-based workflow to capture intra-patient heterogeneity through transcriptional multi-label characterization and clinically relevant classification.

Journal of biomedical informatics
OBJECTIVES: Patient classification into specific molecular subtypes is paramount in biomedical research and clinical practice to face complex, heterogeneous diseases. Existing methods, especially for gene expression-based cancer subtyping, often simp...