PURPOSE: To develop and demonstrate the efficacy of a novel head-and-neck multimodality image registration technique using deep-learning-based cross-modality synthesis.
PURPOSE: Dual-energy computed tomography (DECT) has shown great potential in many clinical applications. By incorporating the information from two different energy spectra, DECT provides higher contrast and reveals more material differences of tissue...
PURPOSE: To train deep learning models to differentiate benign and malignant breast tumors in ultrasound images, we need to collect many training samples with clear labels. In general, biopsy results can be used as benign/malignant labels. However, m...
PURPOSE: We propose a novel domain-specific loss, which is a differentiable loss function based on the dose-volume histogram (DVH), and combine it with an adversarial loss for the training of deep neural networks. In this study, we trained a neural n...
PURPOSE: Radiation dose to cardiac substructures is related to radiation-induced heart disease. However, substructures are not considered in radiation therapy planning (RTP) due to poor visualization on CT. Therefore, we developed a novel deep learni...
PURPOSE: Filtering measured projections with a particular convolutional kernel is an essential step in analytic reconstruction of computed tomography (CT) images. A tradeoff between noise and spatial resolution exists for different choices of reconst...
PURPOSE: Various dose calculation algorithms are available for radiation therapy for cancer patients. However, these algorithms are faced with the tradeoff between efficiency and accuracy. The fast algorithms are generally less accurate, while the ac...
PURPOSE: Accurate segmentation of the prostate on computed tomography (CT) for treatment planning is challenging due to CT's poor soft tissue contrast. Magnetic resonance imaging (MRI) has been used to aid prostate delineation, but its final accuracy...
PURPOSE: The aim of this study was to develop a deep learning (DL) method for generating virtual noncontrast (VNC) computed tomography (CT) images from contrast-enhanced (CE) CT images (VNC ) and to evaluate its performance in dose calculations for h...
PURPOSE: To develop a knowledge-based automated planning pipeline that generates treatment plans without feature engineering, using deep neural network architectures for predicting three-dimensional (3D) dose.
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