AI Medical Compendium Journal:
Molecular genetics and genomics : MGG

Showing 1 to 6 of 6 articles

A comprehensive analysis of stroke risk factors and development of a predictive model using machine learning approaches.

Molecular genetics and genomics : MGG
Stroke is a leading cause of death and disability globally, particularly in China. Identifying risk factors for stroke at an early stage is critical to improving patient outcomes and reducing the overall disease burden. However, the complexity of str...

Differentially used codons among essential genes in bacteria identified by machine learning-based analysis.

Molecular genetics and genomics : MGG
Codon usage bias (CUB), the uneven usage of synonymous codons encoding the same amino acid, differs among genes within and across bacteria genomes. CUB is known to be influenced by gene expression and accordingly, CUB differs between the high-express...

A new linear combination method of haplogroup distribution central vectors to model population admixtures.

Molecular genetics and genomics : MGG
We introduce a novel population genetic approach suitable to model the origin and relationships of populations, using new computation methods analyzing Hg frequency distributions. Hgs were selected into groups which show correlated frequencies in sub...

Host-dependent molecular factors mediating SARS-CoV-2 infection to gain clinical insights for developing effective targeted therapy.

Molecular genetics and genomics : MGG
Coronavirus disease 2019 (COVID-19), a recent viral pandemic that first began in December 2019, in Hunan wildlife market, Wuhan, China. The infection is caused by a coronavirus, SARS-CoV-2 and clinically characterized by common symptoms including fev...

Recent advances on the machine learning methods in predicting ncRNA-protein interactions.

Molecular genetics and genomics : MGG
Recent transcriptomics and bioinformatics studies have shown that ncRNAs can affect chromosome structure and gene transcription, participate in the epigenetic regulation, and take part in diseases such as tumorigenesis. Biologists have found that mos...

Chromosome-wide gene dosage rebalance may benefit tumor progression.

Molecular genetics and genomics : MGG
The high-risk of tumor initiation in patients with Turner syndrome (TS) characterized by X chromosome monosomy in women has been well established and aneuploidy, defined as an abnormal number of chromosomes, is a common feature in human cancer. Howev...