AI Medical Compendium Journal:
Pharmacoepidemiology and drug safety

Showing 11 to 17 of 17 articles

Natural language processing to ascertain two key variables from operative reports in ophthalmology.

Pharmacoepidemiology and drug safety
PURPOSE: Antibiotic prophylaxis is critical to ophthalmology and other surgical specialties. We performed natural language processing (NLP) of 743 838 operative notes recorded for 315 246 surgeries to ascertain two variables needed to study the compa...

The use of natural language processing on narrative medication schedules to compute average weekly dose.

Pharmacoepidemiology and drug safety
PURPOSE: Medications with non-standard dosing and unstandardized units of measurement make the estimation of prescribed dose difficult from pharmacy dispensing data. A natural language processing tool named the SIG extractor was developed to identify...

The use of natural language processing of infusion notes to identify outpatient infusions.

Pharmacoepidemiology and drug safety
PURPOSE: Outpatient infusions are commonly missing in Veterans Health Affairs (VHA) pharmacy dispensing data sets. Currently, Healthcare Common Procedure Coding System (HCPCS) codes are used to identify outpatient infusions, but concerns exist if the...

Use of Machine Learning to Compare Disease Risk Scores and Propensity Scores Across Complex Confounding Scenarios: A Simulation Study.

Pharmacoepidemiology and drug safety
PURPOSE: The surge of treatments for COVID-19 in the second quarter of 2020 had a low prevalence of treatment and high outcome risk. Motivated by that, we conducted a simulation study comparing disease risk scores (DRS) and propensity scores (PS) usi...

How Effective Are Machine Learning and Doubly Robust Estimators in Incorporating High-Dimensional Proxies to Reduce Residual Confounding?

Pharmacoepidemiology and drug safety
BACKGROUND: Residual confounding presents a persistent challenge in observational studies, particularly in high-dimensional settings. High-dimensional proxy adjustment methods, such as the high-dimensional propensity score (hdPS), are widely used to ...

Core Concepts in Pharmacoepidemiology: Principled Use of Artificial Intelligence and Machine Learning in Pharmacoepidemiology and Healthcare Research.

Pharmacoepidemiology and drug safety
Artificial intelligence (AI) and machine learning (ML) are important tools across many fields of health and medical research. Pharmacoepidemiologists can bring essential methodological rigor and study design expertise to the design and use of these t...