Statistical methods in medical research
Apr 9, 2018
Extreme learning machines have gained a lot of attention by the machine learning community because of its interesting properties and computational advantages. With the increase in collection of information nowadays, many sources of data have missing ...
Statistical methods in medical research
Mar 1, 2017
Hospital-specific electronic health record systems are used to inform clinical practice about best practices and quality improvements. Many surgical centers have developed deterministic clinical decision rules to discover adverse events (e.g. postope...
Statistical methods in medical research
Feb 27, 2017
Estimation of common cost-effectiveness measures, including the incremental cost-effectiveness ratio and the net monetary benefit, is complicated by the need to account for informative censoring and inherent skewness of the data. In addition, since t...
Statistical methods in medical research
Jan 8, 2017
In establishing prognostic models, often aided by machine learning methods, much effort is concentrated in identifying good predictors. However, the same level of rigor is often absent in improving the outcome side of the models. In this study, we fo...
Statistical methods in medical research
Dec 15, 2016
Consistency of the propensity score estimators rely on correct specification of the propensity score model. The propensity score is frequently estimated using a main effect logistic regression. It has recently been shown that the use of ensemble mach...
Statistical methods in medical research
May 30, 2016
Machine learning techniques have been previously used to assist clinicians to select embryos for human-assisted reproduction. This work aims to show how an appropriate modeling of the problem can contribute to improve machine learning techniques for ...
Statistical methods in medical research
Sep 18, 2013
BACKGROUND: Recent literature on the comparison of machine learning methods has raised questions about the neutrality, unbiasedness and utility of many comparative studies. Reporting of results on favourable datasets and sampling error in the estimat...
Statistical methods in medical research
Oct 14, 2012
Since its first publication in 2003, the Gene Set Enrichment Analysis method, based on the Kolmogorov-Smirnov statistic, has been heavily used, modified, and also questioned. Recently a simplified approach using a one-sample t-test score to assess en...