The journals of gerontology. Series A, Biological sciences and medical sciences
May 5, 2025
There is an urgent need to develop tools to enable older adults to live healthy, independent lives for as long as possible. To address this need, the National Institute on Aging (NIA) Artificial Intelligence and Technology Collaboratories (AITCs) for...
The journals of gerontology. Series A, Biological sciences and medical sciences
May 5, 2025
BACKGROUND: Physical function is a key determinant of independence among older adults. Yet, there are barriers to assessing physical function in clinic. We developed a wearable geriatric functional assessment system (GFAS) that quickly and effortless...
The journals of gerontology. Series A, Biological sciences and medical sciences
May 5, 2025
Falls are a significant cause of human disability and death. Risk factors include normal aging, neurodegenerative disease, and sarcopenia. Drosophila melanogaster is a powerful model for study of normal aging and for modeling human neurodegenerative ...
The journals of gerontology. Series A, Biological sciences and medical sciences
Apr 7, 2025
Integration of artificial intelligence (AI) in health and healthcare, especially for older adults, has significantly advanced healthcare delivery. AI technologies, with capabilities such as self-learning and pattern recognition, are employed to addre...
The journals of gerontology. Series A, Biological sciences and medical sciences
Sep 1, 2024
Large Language Models (LLMs) stand on the brink of reshaping the field of aging and dementia care, challenging the one-size-fits-all paradigm with their capacity for precision medicine and individualized treatment strategies. The "Large Pre-Trained M...
The journals of gerontology. Series A, Biological sciences and medical sciences
Aug 1, 2024
BACKGROUND: Older adults (≥65 years) account for a disproportionately high proportion of hospitalization and in-hospital mortality, some of which may be avoidable. Although machine learning (ML) models have already been built and validated for predic...
The journals of gerontology. Series A, Biological sciences and medical sciences
May 1, 2024
BACKGROUND: Prognostic indices can enhance personalized predictions of health burdens. However, a simple, practical, and reproducible tool is lacking for clinical use. This study aimed to develop a machine learning-based prognostic index for predicti...
The journals of gerontology. Series A, Biological sciences and medical sciences
May 5, 2022
BACKGROUND: Mobility limitation in older adults is common and associated with poor health outcomes and loss of independence. Identification of at-risk individuals remains challenging because of time-consuming clinical assessments and limitations of s...
The journals of gerontology. Series A, Biological sciences and medical sciences
Mar 3, 2022
BACKGROUND: Delirium is underdiagnosed in clinical practice and is not routinely coded for billing. Manual chart review can be used to identify the occurrence of delirium; however, it is labor-intensive and impractical for large-scale studies. Natura...