AIMC Topic: Adenosine

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iMethyl-STTNC: Identification of N-methyladenosine sites by extending the idea of SAAC into Chou's PseAAC to formulate RNA sequences.

Journal of theoretical biology Jul 19, 2018
N- methyladenosine (mA) is a vital post-transcriptional modification, which adds another layer of epigenetic regulation at RNA level. It chemically modifies mRNA that effects protein expression. RNA sequence contains many genetic code motifs (GAC). A...
Sequence Analysis, RNA Support Vector Machine RNA Neural Networks, Computer Base Sequence Adenosine
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Kinematics optimization and static analysis of a modular continuum robot used for minimally invasive surgery.

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine Dec 11, 2017
For the outstanding compliance and dexterity of continuum robot, it is increasingly used in minimally invasive surgery. The wide workspace, high dexterity and strong payload capacity are essential to the continuum robot. In this article, we investiga...
Motion Adenosine Biomechanical Phenomena Robotics Minimally Invasive Surgical Procedures Equipment Design
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Identifying N-methyladenosine sites using multi-interval nucleotide pair position specificity and support vector machine.

Scientific reports Apr 25, 2017
N6-methyladenosine (mA) refers to methylation of the adenosine nucleotide acid at the nitrogen-6 position. It plays an important role in a series of biological processes, such as splicing events, mRNA exporting, nascent mRNA synthesis, nuclear transl...
Adenosine Arabidopsis Nucleotides Datasets as Topic Saccharomyces cerevisiae RNA, Messenger Support Vector Machine Humans Algorithms Computational Biology
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Detecting N-methyladenosine sites from RNA transcriptomes using ensemble Support Vector Machines.

Scientific reports Jan 12, 2017
As one of the most abundant RNA post-transcriptional modifications, N-methyladenosine (mA) involves in a broad spectrum of biological and physiological processes ranging from mRNA splicing and stability to cell differentiation and reprogramming. Howe...
Saccharomyces cerevisiae Adenosine RNA Processing, Post-Transcriptional Computational Biology Transcriptome Support Vector Machine RNA
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TargetM6A: Identifying N-Methyladenosine Sites From RNA Sequences via Position-Specific Nucleotide Propensities and a Support Vector Machine.

IEEE transactions on nanobioscience Aug 10, 2016
As one of the most ubiquitous post-transcriptional modifications of RNA, N-methyladenosine ( [Formula: see text]) plays an essential role in many vital biological processes. The identification of [Formula: see text] sites in RNAs is significantly imp...
Computational Biology Sequence Analysis, RNA Support Vector Machine RNA Saccharomyces cerevisiae Adenosine
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Dynamic regulation of RNA editing in human brain development and disease.

Nature neuroscience Jun 27, 2016
RNA editing is increasingly recognized as a molecular mechanism regulating RNA activity and recoding proteins. Here we surveyed the global landscape of RNA editing in human brain tissues and identified three unique patterns of A-to-I RNA editing rate...
Inosine RNA Editing Diagnosis Adenosine Humans Adenosine Deaminase Brain RNA-Binding Proteins Gene Ontology
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Myocardial Fractional Flow Reserve Measurement Using Contrast Media as a First-Line Assessment of Coronary Lesions in Current Practice.

The Canadian journal of cardiology Sep 25, 2015
BACKGROUND: Fractional flow reserve (FFR) measurement requires adenosine injection. However, adenosine can induce conductive and rhythmic complications, or be contraindicated in some patients. Contrast-induced hyperemia could provide a simple first-l...
Coronary Angiography Middle Aged Aged Female Patient Selection Risk Assessment Adenosine Contrast Media Reproducibility of Results Sensitivity and Specificity France Body Mass Index Humans Predictive Value of Tests Triiodobenzoic Acids Risk Factors Male Prospective Studies Coronary Stenosis Fractional Flow Reserve, Myocardial
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Characterization of m6A-Related Genes in Tumor-Associated Macrophages for Prognosis, Immunotherapy, and Drug Prediction in Lung Adenocarcinomas Based on Machine Learning Algorithms.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jun 15, 2025
Tumor-associated macrophages (TAMs) are a vital immune component within the tumor microenvironment (TME) of lung adenocarcinoma (LUAD), exerting significant influence on tumor growth, metastasis, and drug resistance. N6-methyladenosine (m6A) modifica...
Adenosine Tumor-Associated Macrophages Adenocarcinoma of Lung Prognosis Tumor Microenvironment Lung Neoplasms Humans Biomarkers, Tumor Immunotherapy Machine Learning Gene Expression Regulation, Neoplastic Algorithms
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m6A-SPP: Identification of RNA N6-methyladenosine modification sites through multi-source biological features and a hybrid deep learning architecture.

International journal of biological macromolecules Jun 1, 2025
The N6-methyladenosine(m6A) modification plays crucial regulatory roles in various biological processes including gene expression regulation, RNA stability, splicing, and translation. Accurate prediction of m6A modification sites is essential for und...
Humans Methylation Neural Networks, Computer HEK293 Cells Deep Learning Adenosine Computational Biology RNA HeLa Cells
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DTC-m6Am: A Framework for Recognizing N6,2'-O-dimethyladenosine Sites in Unbalanced Classification Patterns Based on DenseNet and Attention Mechanisms.

Frontiers in bioscience (Landmark edition) Apr 24, 2025
BACKGROUND: mAm is a specific RNA modification that plays an important role in regulating mRNA stability, translational efficiency, and cellular stress response. mAm's precise identification is essential to gain insight into its functional mechanisms...
Transcriptome Deep Learning Convolutional Neural Networks Humans Computational Biology Adenosine
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