AIMC Topic: Algorithms

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Learning to match patients to clinical trials using large language models.

Journal of biomedical informatics
OBJECTIVE: This study investigates the use of Large Language Models (LLMs) for matching patients to clinical trials (CTs) within an information retrieval pipeline. Our objective is to enhance the process of patient-trial matching by leveraging the se...

High-precision identification of highly similar Pinelliae Rhizoma and adulterated Rhizoma pinelliae pedatisectae through deep neural networks based on vision transformers.

Journal of food science
Pinelliae Rhizoma is a key ingredient in botanical supplements and is often adulterated by Rhizoma Pinelliae Pedatisectae, which is similar in appearance but less expensive. Accurate identification of these materials is crucial for both scientific an...

Development of HepatIA: A computed tomography annotation platform and database for artificial intelligence training in hepatocellular carcinoma detection at a Brazilian tertiary teaching hospital.

Clinics (Sao Paulo, Brazil)
BACKGROUND: Hepatocellular carcinoma (HCC) is a prevalent tumor with high mortality rates. Computed tomography (CT) is crucial in the non-invasive diagnosis of HCC. Recent advancements in artificial intelligence (AI) have shown significant potential ...

Evaluating Explainable Artificial Intelligence (XAI) techniques in chest radiology imaging through a human-centered Lens.

PloS one
The field of radiology imaging has experienced a remarkable increase in using of deep learning (DL) algorithms to support diagnostic and treatment decisions. This rise has led to the development of Explainable AI (XAI) system to improve the transpare...

Identification of Spared and Proportionally Controllable Hand Motor Dimensions in Motor Complete Spinal Cord Injuries Using Latent Manifold Analysis.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
The loss of bilateral hand function is a debilitating challenge for millions of individuals that suffered a motor-complete spinal cord injury (SCI). We have recently demonstrated in eight tetraplegic individuals the presence of highly functional spar...

Adapting Action Recognition Neural Networks for Automated Infantile Spasm Detection.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Infantile spasms are a severe epileptic syndrome characterized by short muscular contractions lasting from 0.5 to 2 seconds. They are often misdiagnosed due to their atypical presentation, and treatment is frequently delayed, leading to stagnation or...

A Knowledge-Driven Self-Supervised Approach for Molecular Generation.

IEEE/ACM transactions on computational biology and bioinformatics
Due to the great successes of Graph Neural Networks (GNN) in numerous fields, growing research interests have been devoted to applying GNN to molecular learning tasks. The molecule structure can be naturally represented as graphs where atoms and bond...

RDGAN: Prediction of circRNA-Disease Associations via Resistance Distance and Graph Attention Network.

IEEE/ACM transactions on computational biology and bioinformatics
As a series of single-stranded RNAs, circRNAs have been implicated in numerous diseases and can serve as valuable biomarkers for disease therapy and prevention. However, traditional biological experiments demand significant time and effort. Therefore...

Molecular Design Based on Integer Programming and Splitting Data Sets by Hyperplanes.

IEEE/ACM transactions on computational biology and bioinformatics
A novel framework for designing the molecular structure of chemical compounds with a desired chemical property has recently been proposed. The framework infers a desired chemical graph by solving a mixed integer linear program (MILP) that simulates t...

Drug-Target Binding Affinity Prediction in a Continuous Latent Space Using Variational Autoencoders.

IEEE/ACM transactions on computational biology and bioinformatics
Accurate prediction of Drug-Target binding Affinity (DTA) is a daunting yet pivotal task in the sphere of drug discovery. Over the years, a plethora of deep learning-based DTA models have emerged, rendering promising results in predicting the binding...