OBJECTIVE: In the attempt of early diagnosis of Alzheimer's Disease, varying forms of medical records of multiple modalities are gathered to seize the interaction of multiple factors. However, the heterogeneity of multimodal data brings a challenge. ...
OBJECTIVE: To identify blood-based biomarkers and therapeutic targets for Alzheimer's disease (AD) by leveraging single-cell RNA sequencing (scRNA-seq) data from peripheral blood mononuclear cells (PBMCs) and advanced deep learning techniques.
BACKGROUND: Magnetic resonance imaging (MRI), combined with artificial intelligence techniques, has improved our understanding of brain structural change and enabled the estimation of brain age. Neurodegenerative disorders, such as Alzheimer's diseas...
With all the advances in both the science of aging and artificial intelligence (AI), we are in a propitious position to accurately and precisely determine who is at high risk of developing Alzheimer's disease years before signs of even mild cognitive...
Alzheimer's disease (AD) is the most prevalent type of dementia. It is linked with a gradual decline in various brain functions, such as memory. Many research efforts are now directed toward non-invasive procedures for early diagnosis because early d...
BACKGROUND: Movement patterns, activity levels and circadian rhythm are altered in Alzheimer's disease (AD) and can be assessed by actigraphy using wearable sensors. We aimed to determine the diagnostic performance of actigraphy in AD in a memory cli...
Biomedical physics & engineering express
May 21, 2025
Alzheimer's disease (AD), a progressive neurodegenerative disorder, is the leading cause of dementia worldwide and remains incurable once it begins. Therefore, early and accurate diagnosis is essential for effective intervention. Leveraging recent ad...
Dementia spectrum disorders, characterized by progressive cognitive decline, pose a significant global health burden. Early screening and diagnosis are essential for timely and accurate treatment, improving patient outcomes and quality of life. This ...
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that severely affects memory, behavior, and cognitive function. Early and accurate diagnosis is crucial for effective intervention, yet detecting subtle changes in the early stages ...
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