BACKGROUND: Recently, many studies have been carried out to detect Alzheimer's disease (AD) from continuous speech by linguistic analysis and modeling. However, few of them utilize language models (LMs) to extract linguistic features and to investiga...
BACKGROUND: Memory dysfunction is characteristic of aging and often attributed to Alzheimer's disease (AD). An easily administered tool for preliminary assessment of memory function and early AD detection would be integral in improving patient manage...
The journal of prevention of Alzheimer's disease
Jan 1, 2019
BACKGROUND: Recruiting patients for clinical trials of potential therapies for Alzheimer's disease (AD) remains a major challenge, with demand for trial participants at an all-time high. The AD treatment R and D pipeline includes around 112 agents. I...
Accurate and early diagnosis of Alzheimer's disease (AD) plays important role for patient care and development of future treatment. Structural and functional neuroimages, such as magnetic resonance images (MRI) and positron emission tomography (PET),...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2018
Alzheimer's disease (AD), a progressive brain disorder, is the most common neurodegenerative disease in older adults. There is a need for brain structural magnetic resonance imaging (MRI) biomarkers to help assess AD progression and intervention effe...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2018
Electroencephalogram (EEG) signal based early diagnosis of Alzheimer's Disease (AD), especially a discrimination between healthy control (HC) and mild cognitive impairment (MCI) has received remarkable attentions to complement conventional diagnosing...
BACKGROUND: Virtual Screening (VS) has emerged as an important tool in the drug development process, as it conducts efficient in silico searches over millions of compounds, ultimately increasing yields of potential drug leads. As a subset of Artifici...
Naodesheng (NDS) formula, which consists of Rhizoma Chuanxiong, Lobed Kudzuvine, Carthamus tinctorius, Radix Notoginseng, and Crataegus pinnatifida, is widely applied for the treatment of cardio/cerebrovascular ischemic diseases, ischemic stroke, and...